Downstream effects: Comment on retracted narcolepsy paper retracted

stmcoverThe recent retraction of a paper in Science Translational Medicine reporting “one of the biggest things to happen” in narcolepsy research has claimed a bystander: A letter that commented on the no-longer-landmark article.

The authors of the letter are with GlaxoSmithKline’s vaccine division. Here’s the new notice: Continue reading Downstream effects: Comment on retracted narcolepsy paper retracted

Data questions prompt retraction of PLOS ONE cardiovascular paper

plosonePLoS One has retracted a 2013 article on atherosclerosis in mice over concerns about the integrity of the data.

The paper, “The Effect of Soluble RAGE on Inhibition of Angiotensin II-Mediated Atherosclerosis in Apolipoprotein E Deficient Mice,” came from a group of researchers in South Korea.

It purported to show that: Continue reading Data questions prompt retraction of PLOS ONE cardiovascular paper

Researcher who broke into lab up to nine retractions

bichaw_v053i036.inddKarel Bezouška, a researcher who broke into a lab refrigerator to tamper with an investigation into his work, has nine retractions.

Here’s the retraction notice in Biochemistry for 2010’s “Cooperation between Subunits Is Essential for High-Affinity Binding of N-Acetyl-d-hexosamines to Dimeric Soluble and Dimeric Cellular Forms of Human CD69:” Continue reading Researcher who broke into lab up to nine retractions

A PNAS expression of concern appears — and so does its revealing backstory

pnas 1113When retraction notices and expressions of concern appear, particularly those that are opaque, we try our best to find out what’s behind them, whether it’s better explanations or the steps that led to moves. Today, we have one story in which we’ve been able to learn a lot more than usual.

In April, Bas van Steensel, Wendy Bickmore, Thomas Cremer, and Kerstin Bystricky sent a letter to about 80 leading labs in nuclear organization and steroid receptor biology. It began (we’ve added some relevant links): Continue reading A PNAS expression of concern appears — and so does its revealing backstory

Scientist in Ireland notches two mysterious retractions and a correction

Sinead Miggin, via NUIM
Sinead Miggin, via NUIM

Sinead Miggin, a biologist at the National University of Ireland Maynooth, has withdrawn two papers from the Journal of Biological Chemistry (JBC) and has corrected another paper, in the Proceedings of the National Academy of Sciences (PNAS).

Here’s the opaque JBC notice for “14-3-3ϵ and 14-3-3σ inhibit Toll-like receptor (TLR)-mediated proinflammatory cytokine induction,” a paper first published in November 2012: Continue reading Scientist in Ireland notches two mysterious retractions and a correction

Authors retract PNAS brain genetics paper for statistical issues

pnas 1113The authors of a paper on brain genetics published online in June in the Proceedings of the National Academy of Sciences (PNAS) are retracting it for “a potential confound relating to statistical inference.”

Here’s the notice for “Identification of gene ontologies linked to prefrontal–hippocampal functional coupling in the human brain:” Continue reading Authors retract PNAS brain genetics paper for statistical issues

First author blamed for retraction in prestigious medical journal

jemcoverThe authors of a Journal of Experimental Medicine have retracted it, blaming the first author for data and figure manipulation.

The paper, “The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells,” was initially published in September 2011 and has been cited 25 times, according to Thomson Scientific’s Web of Knowledge. First author Jiyeon Kim was an MD-PhD candidate at the University of Pennsylvania until this year, according to a LinkedIn profile.

Here’s the notice: Continue reading First author blamed for retraction in prestigious medical journal

Diabetes researcher Cory Toth now up to nine retractions

neuroscienceCory Toth is up to nine retractions.

The University of Calgary researcher who told us earlier this year that he “will not be publishing in the world of science in the future” has retracted two papers from Neuroscience.

Here’s the notice for “Local erythropoietin signaling enhances regeneration in peripheral axons:” Continue reading Diabetes researcher Cory Toth now up to nine retractions

Déjà vu: Double pub in the same issue earns a retraction

biomedchromAlways do a careful reading of your galleys, editors.

We imagine readers of Biomedical Chromatography’s special issue, “Reminiscences of Chang Kee Lim,” did some flipping back and forth when they found the same paper published twice.

Here’s the resulting notice for “Determination of 4-hydroxy-2-nonenal in serum by high-performance liquid chromatography with fluorescence detection after pre-column derivatization using 4-(N,N-dimethylaminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole”:  Continue reading Déjà vu: Double pub in the same issue earns a retraction

Journal takes down autism-vaccine paper pending investigation

translational neurodegenerationAn article purporting to find that black children are at substantially increased risk for autism after early exposure to the measles-mumps-rubella vaccine has been shelved.

Although we don’t know if the events are related, the move comes amid claims that a CDC whistleblower has accused health officials of suppressing information about the link.

Not surprisingly, the prospect that the CDC has been sitting on evidence of an autism-vaccine connection for more than a decade has inflamed the community of activists wrongly convinced that such a link exists.

The paper, “Measles-mumps-rubella vaccination timing and autism among young african american boys: a reanalysis of CDC data,” was written by Brian Hooker, an engineer-turned-biologist and an active member of that community. It was submitted in April, accepted on August 5, and published on August 8.

Translational Neurodegeneration, which published the article earlier this month, has now removed it and posted the following notice: Continue reading Journal takes down autism-vaccine paper pending investigation