Critics of 2008 concussion study failed to note NFL ties

Jama neurWhen a 2008 paper proposed that athletes be kept out of play for four weeks following a concussion, three doctors wrote in to say that the recommendations were “irrelevant and ill advised.” One thing the trio failed to disclose, however, was their own financial ties to the National Football League.

With the release of the 2013 Frontline documentary “League of Denial: The NFL’s Concussion Crisis” and the publication of Concussion by journalist Jeanne-Marie Laskas, the evidence is growing that the NFL — with the help of doctors working as paid consultants or expert witnesses for the NFL or individual teams  — has downplayed the potential of football to cause long-term brain injuries.

In a 2008, Lester Mayers of Pace University in Pleasantville, New York, published a review paper in Archives of Neurology (now JAMA Neurology), that summarized evidence from tests such as balance and gait testing, along with MRI and PET imaging studies. Mayers, who is now deceased, concluded in “Return-to-Play Criteria After Athletic Concussion: A Need for Revision” that it takes at least four weeks — rather than one or two — for the brain to heal following a concussion:

Continue reading Critics of 2008 concussion study failed to note NFL ties

“Compromised” peer review hits three papers from Nature Publishing Group

company-info-big

Nature Publishing Group is retracting three papers today, after an investigation found evidence the peer-review process had been compromised.

The publisher issued a statement saying they had notified corresponding authors and institutions associated with the three papers, which were all published last year in the journals Cancer Gene Therapy and Spinal Cord. 

Here’s the note that’s going on each of the papers, (they’re the same, except for the publication date):

Continue reading “Compromised” peer review hits three papers from Nature Publishing Group

Fifth retraction for Wayne State researcher who fudged figures

teresita
Teresita L. Briones

Another retraction has appeared for Teresita Briones, who used to study neuroscience at Wayne State University — the final of five papers flagged by the Office of Research Integrity for containing falsified data.

According to the ORI notice published in May, Briones “intentionally, knowingly, and recklessly engaged in research misconduct by falsifying and/or fabricating data.” This latest paper to be retracted, which looks at the role of specific receptor in chronic inflammation of nervous tissue in rats, has two figures that “were duplicated, reused and falsely relabelled, and claimed to represent different experiments,” according to the retraction note.

The retraction note for “Chronic neuroinflammation and cognitive impairment following transient global cerebral ischemia: role of fractalkine/CX3CR1 signaling,” published in the Journal of Neuroinflammation, specifies the problematic figures:

Continue reading Fifth retraction for Wayne State researcher who fudged figures

My life as a whistleblower: Q&A with Peter Wilmshurst

We’re presenting a Q&A session with Peter Wilmshurst, now a part-time consultant cardiologist who has spent decades embroiled in misconduct investigations as a whistleblower.

Dr-Peter-Wilmshurst-007
Peter Wilmshurst

Retraction Watch: A UK judge recently upheld two findings of dishonesty by the Medical Practitioners Tribunal Service against Andrew Dowson, director of headache services at King’s College Hospital and your former co-investigator. Were you pleased with the verdict? (Last week, Dowson also began a four-month suspension from practicing medicine in the UK.) 

Peter Wilmshurst: In part, because I was pleased that he was shown to be dishonest, because I knew that he was, which was why I reported him. But I wasn’t pleased in the sense that I don’t think the investigation dealt with all the issues involved in the Migraine Intervention with STARflex Technology (MIST) Trial.

RW: What additional issues did you hope to see addressed? Continue reading My life as a whistleblower: Q&A with Peter Wilmshurst

Authors retract two neuroscience papers for duplication and plagiarism

Journal of NeurosurgeryA tipster’s complaints have led to the retraction of two papers in the Journal of Neurosurgery for “plagiarism, duplicate publication, and copyright infringement.”

The corresponding author for both papers, Hung-Chuan Pan of Taichung Veterans General Hospital, had contacted the journal about publishing an erratum for one of the articles when the journal was tipped off by an email pointing out deeper problems in the two retracted papers.

The tipster provided evidence that alleged “a violation of ethics on the part of the authors,” according to the communications manager at the JNS Publishing Group, Jo Ann Eliason.

Both retraction notices, published October 2, detailed a number of “similarities” and “overlaps” in the papers.

Continue reading Authors retract two neuroscience papers for duplication and plagiarism

Journal retracts — and republishes — small study on gamma rays for OCD

Screen Shot 2015-10-28 at 8.40.00 PMJAMA Psychiatry has retracted and republished a paper on a cutting-edge procedure for patients with obsessive compulsive disorder.

In the original paper, the authors claimed that three out of eight patients who underwent a procedure that used gamma rays to kill brain cells showed improvements 12 months later (versus zero in the group who underwent a “sham” procedure). But after a reader noticed an “inadvertent” error in the calculation of how many patients had improved, the authors realized that only two of the patients had responded meaningfully to the procedure.

The new results “did not reach statistical significance,” the authors write in a “Notice of Retraction and Replacement.”  JAMA Psychiatry published it yesterday, along with a new version of the articlea letter from psychiatrist Christopher Baethge pointing out the error, and an editorial. The original article is available in the supplemental material of the new version, with the errors highlighted.

Here’s the note in full for “Gamma ventral capsulotomy for obsessive-compulsive disorder: a randomized clinical trial,” which explains the error:

Continue reading Journal retracts — and republishes — small study on gamma rays for OCD

Taste researcher falsified data in two papers: ORI

ori-logoA federal report has found that a former University of Maryland postdoc “falsified and/or fabricated” data in two papers about taste receptors.

The Office of Research Integrity report found that Maria C.P. Geraedts manipulated bar graphs in the papers to “produce the desired result.” Both have been retracted. Geraedts left academia in 2014, and is now a science writer.

We reported on one retraction in July, “Gustatory stimuli representing different perceptual qualities elicit distinct patterns of neuropeptide secretion from taste buds,” published in The Journal of Neuroscience.

The other, “Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery,” published in 2012 in the American Journal of Physiology Endocrinology and Metabolism, was retracted in September. Here’s the note, which cites the university’s investigation: Continue reading Taste researcher falsified data in two papers: ORI

Journal mistakenly publishes Parkinson’s case report twice

Journal of Movement Disorders

A journal has retracted a duplicate version of a case report about a patient with Parkinson’s disease after mistakenly publishing the paper twice.

The Journal of Movement Disorders initially published the report — which detailed the case of an elderly woman with Parkinson’s disease whose symptoms worsened during drug treatment — in 2010. But it ended up printing it again in 2011 because of “a mistake of the editorial office and the publisher.”

The notice reads:

Continue reading Journal mistakenly publishes Parkinson’s case report twice

Danish neuroscientist sentenced by court for lying about faked experiments

court caseIn a rare development, neuroscientist Milena Penkowa has been sentenced by a Danish court for faking data.

The ruling, from the Copenhagen City Court, resulted from Penkowa’s publication of her 2003 thesis describing experiments that she never carried out. The court “placed weight” on the fact that she didn’t just commit fraud, but “systematically supplied false information” to avoid being caught, according to the court’s notice.

The sentence is nine months of “conditional imprisonment,” according to our translation; The University Posta newspaper affiliated with the University of Copenhagen, calls it a “nine month suspended sentence with a two years probation.”

Here’s the full summary of the new ruling, from the Copenhagen City Court (translated from Danish by One Hour Translation):

Continue reading Danish neuroscientist sentenced by court for lying about faked experiments

NIH rescinds grant to Texas eye researcher

banner-nihlogoA scientist who uses imaging to study the eye and brain has lost a major grant from the U.S. National Institutes of Health.

In June, the NIH revised the award for Timothy Duong at the University of Texas Health Science Center at San Antonio from $332,500 per year to $0, and included this statement: Continue reading NIH rescinds grant to Texas eye researcher