A group of researchers in the Netherlands has retracted a paper once they realized that the findings weren’t reproducible and that there had been an error in the experiments.
Here’s the notice for “Ubiquitin‐specific protease 4 is inhibited by its ubiquitin‐like domain,” by MP Luna‐Vargas, AC Faesen, WJ van Dijk, M Rape, A Fish, and TK Sixma: Continue reading Doing the right thing: Authors retract protein paper after finding experimental errors
A research group in Scotland has retracted a paper in the Biochemical Journal after failed attempts to reproduce a key finding of the study.
Here’s the notice: Continue reading Failure to reproduce result leads to disputed retraction
The Journal of the American Chemical Society has retracted a 2009 paper on ethylene polymerization after the authors said they were unable to replicate their findings.
The article, “Bimetallic Effects for Enhanced Polar Comonomer Enchainment Selectivity in Catalytic Ethylene Polymerization,”came from the lab of Tobin Marks, a highly decorated — and grant-and-royalty-generating — chemist at Northwestern University.
Continue reading JACS retracts polymer paper over data concerns
Nature has retracted a controversial 2012 paper by a group from Johns Hopkins University which has been the subject of a protracted public dispute.
The article, “Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK,” came from the lab of Jef Boeke, a celebrated biochemist. But a former lab member, Daniel Yuan, who was fired by Hopkins in late 2011 after 10 years at the institution, had repeatedly raised questions about the validity of the findings. Those concerns eventually made their way into the Washington Post, prompting this response from the university. Continue reading Nature yanks controversial genetics paper whose co-author was found dead in lab in 2012
Two American College of Cardiology conference abstracts published earlier this year in the Journal of the American College of Cardiology (JACC) have been retracted, one because the authors were actually measuring something other than what they reported, and the other because newer software invalidated the results.
Here’s the notice for “Worsening of Pre-Existing Valvulopathy With A New Obesity Drug Lorcaserin, A Selective 5-Hydroxytryptamine 2C Receptor Agonist: A Meta-Analysis of Randomized Controlled Trials” by Hemang B. Panchal, Parthav Patel, Brijal Patel, Rakeshkumar Patel, and Henry Philip of East Tennessee State University: Continue reading Two detailed retraction notices correct the cardiology record
A team of researchers led by Daniel St. Johnston, director of the Gurdon Institute at Cambridge and a prominent developmental biologist in the UK, has lost a pair of articles after finding that their data were unreliable. But rather than “correct” the record with subsequent papers, they’ve withdrawn the problematic work.
To our mind, this is a poster case of doing the right thing by science. We think the notices — as provided by the authors and reported by the journals — pretty much say it all, so we’ll let them speak for themselves, followed by some details St. Johnston shared with us.
The first article, “LKB1 and AMPK maintain epithelial cell polarity under energetic stress,” appeared in 2007 in the Journal of Cell Biology and has been cited 108 times, according to Thomson Scientific’s Web of Knowledge.
According to the retraction notice:
Ariel Fernández, the protein researcher whose theories of drug design lately have come in for questioning, has lost a paper, at least for the moment.
The article, “Supramolecular Evolution of Protein Organization,” appeared online in Annual Reviews of Genetics prior to print. It lists Fernández’s affiliation as ProWD Sciences, in Madison, Wisc. Not much exists on the web about that company, however, except an under-construction site. (ProWD, by the way, is short for PROtein-Water-Dehydron, Fernández’s area of interest.)
Here’s the notice: Continue reading Fernández genetics paper in limbo over data concerns
About a month ago, we reported on a retraction by Pamela Ronald, of the University of California, Davis, and colleagues. We noted then that this was a case of scientists doing the right thing. Ronald contacted us after that post ran, and let us know that there would be another retraction shortly. That retraction notice has now appeared, in Science: Continue reading Pamela Ronald does the right thing again, retracting a Science paper
Stem Cells and Development has retracted a paper it published earlier this year after the leader of the study reported that the data were unreliable.
The paper, “Derivation and Genetic Modification of Embryonic Stem Cells from Disease-Model Inbred Rat Strains,” came from the lab of Aron Geurts, of the Medical College of Wisconsin.
According to the retraction notice: Continue reading Embryonic stem cell paper retracted for fabrication
A materials scientist in Turkey has retracted a paper in the journal Tetrahedron after realizing that there was more to the compounds he was studying than he thought.
The article, “Novel donor–acceptor type thiophene pyridine conjugates: synthesis and ion recognition features,” appeared in April and was written by Fatih Algi, of the Laboratory of Organic Materials at Canakkale Onsekiz Mart University.
Here’s the notice: Continue reading Author retracts materials paper for irreproducibility