Update on mysterious JACI retraction: Data were falsified

Since the weekend, we’ve been trying to get more details on a somewhat mysterious retraction in the Journal of Allergy and Clinical Immunology. The sparse notice really only said that there were “data inconsistencies” that made the data unreliable.

On Monday, as we noted in an update to the post yesterday, we learned:

The inconsistencies related to what an individual’s lab-book recorded in terms of patients and infections. These came to light when this data was compared to hospital records, during the process of manuscript preparation. As noted, we reported our concerns about the validity of the data and following a review, there was no adequate explanation and the concerns remained.

We still couldn’t tell whether this was error or falsification. Late last night, we got the answer from co-author Euan Tovey: Continue reading Update on mysterious JACI retraction: Data were falsified

A mysterious retraction in the Journal of Allergy and Clinical Immunology

The Journal of Allergy and Clinical Immunology has retracted a 2009 abstract, but don’t ask us why. The retraction notice for “Children with asthma and no URTI, more commonly have rhinovirus in their exhaled breath, than in mucous,” is another one we’ll file under “opaque“: Continue reading A mysterious retraction in the Journal of Allergy and Clinical Immunology

Exclusive: Researcher found guilty of misconduct at UCL had been dismissed from Cambridge for data fabrication

Here at Retraction Watch, we’ve been following the case of Jatinder Ahluwalia with interest. You may recall that an investigation by University College London (UCL) found “beyond reasonable doubt” that Ahluwalia had renumbered files to deceive a co-author. UCL was also “highly confident” that Ahluwalia had messed with his solutions to make his results look better, and sabotaged his colleagues’ work. The report of that investigation was part of a Nature retraction notice.

We’ve now learned that UCL was not the first scene of misconduct by Ahluwalia. Yesterday, we obtained letters by University of Cambridge faculty and administrators describing repeated — and in the words of of one professor, amateurish — data fabrication by Ahluwalia that led to his dismissal from the university’s graduate program.

In a letter dated November 10, 1997, Martin Brand, then Ahluwalia’s PhD advisor, wrote: Continue reading Exclusive: Researcher found guilty of misconduct at UCL had been dismissed from Cambridge for data fabrication

Lab gadfly PETA pressures AACR, gets retraction from sanctioned scientist

People for the Ethical Treatment of Animals (PETA) may not be on most scientists’ list of Facebook friends, but we’re grateful to them for a hat tip. Several days ago, we were approached by Justin Goodman, associate director of PETA’s laboratory investigations department, with a new twist on an old story.

First, a little history: In September 2009, the Office of Research Integrity sanctioned an ex-Vanderbilt cancer researcher named Nagendra S. Ningaraj. According to the agency, Ningaraj Continue reading Lab gadfly PETA pressures AACR, gets retraction from sanctioned scientist

Some quick thoughts and links on Andrew Wakefield, the BMJ, autism, vaccines, and fraud

If you’re a savvy Retraction Watch reader — or if you’ve paid any attention at all to the news in the last 18 hours — you will have heard by now that the BMJ has called Andrew Wakefield’s work on autism and the MMR vaccine a “hoax.”

The February 2010 retraction of the original Wakefield paper in the Lancet was, of course, a huge deal. If there were a Canon of Scientific Retractions, it would be in it. It happened before we launched Retraction Watch, however, so we haven’t commented much on it.

We plan on writing about major retractions in history, but the frequency of fascinating timely ones hasn’t abated enough yet to let us do that. (One exception: Our Best of Retractions series.) And in any case, there have been a lot of pixels spilled on this one already, so we’re not sure we have much to add. That’s the nice thing about the web: It leaves us free to curate as well as create.

One comment we want to offer is that the investigation by Brian Deer in the BMJ Continue reading Some quick thoughts and links on Andrew Wakefield, the BMJ, autism, vaccines, and fraud

Update on the Gressner case: Son Olav says he’s the unfairly targeted “bête noire”

We have an update on the case of Olav and Axel Gressner, a father-son (or, in this case, son-father) pair of German liver researchers caught up in a fraud investigation. The inquiry focused on Olav, who left the University of Aachen under a cloud of suspicion. A 2008 research letter on which he was a co-author (his father was senior author) was retracted earlier this year by the Journal of Hepatology.

The journal’s position in the retraction notice,  published online in June and in print in September, bears repeating here. The authors: Continue reading Update on the Gressner case: Son Olav says he’s the unfairly targeted “bête noire”

ORI comes down (hard) on Bengu Sezen, Columbia chemist accused of fraud

The Office of Research Integrity has thrown a heavy book at Bengu Sezen, a former chemist at Columbia University, alleging that school and agency investigators turned up 21 instances of research misconduct by the disgraced scientist.

According to the agency: Continue reading ORI comes down (hard) on Bengu Sezen, Columbia chemist accused of fraud

It’s poll time: Should a retraction during graduate school mean losing your PhD?

photo by secretlondon123 via flickr http://www.flickr.com/photos/secretlondon/

A few weeks ago, we reported on the case of Emily Horvath, a promising scientist at Indiana University who admitted to falsifying data to make her results look better. Some of that data went into her PhD thesis. That prompted a Retraction Watch reader to ask whether scientists who commit such fraud should be stripped of their PhDs. We figured that was a good poll question, so let us know what you think.

More on Ahluwalia et al Nature retraction, from Tom DeCoursey

Yesterday,we posted on the retraction of a 2004 Nature paper on innate immunity whose findings had been questioned by two groups. A few hours after we posted that item, we heard back from the senior author of one of the papers doubting that data, Tom DeCoursey. DeCoursey makes a number of important points, so we thought it would be a good idea to share them as a post: Continue reading More on Ahluwalia et al Nature retraction, from Tom DeCoursey

Previously questioned Nature paper on innate immunity retracted

courtesy Nature

Last week, we noted a Nature editorial in which the journal came clean about its higher-than-average number of retractions this year — four. What we missed was the fact that the fourth retraction of the year also appeared in last week’s issue.

The retraction, of a paper called “The large-conductance Ca2+-activated K+ channel is essential for innate immunity,” reads (link to the author’s homepage added): Continue reading Previously questioned Nature paper on innate immunity retracted