Category: expression of concern

Three HER2-cancer review papers tagged with expressions of concern

The Oncologist Her 2 expression of concern

The Oncologist has tagged three review papers that share a first author with an expression of concern. The three papers, which have together been cited more than 1,000 times, focus on HER2, a gene that can contribute to breast cancer.

Though the papers contain errors, the conclusions — about how the HER2 gene serves as a predictive factor for breast cancer, and a target for therapies — remain unchanged, according to the EOC. The editor of the journal notes that the conclusions of the papers have been confirmed by other publications. Two of the papers are more than 10 years old, and today many patients continue to be treated with medications that target HER2, such as Herceptin.

Here’s the expression of concern:

Continue reading Three HER2-cancer review papers tagged with expressions of concern

Cell Press flags two papers after author confesses to fraud

Screen Shot 2016-04-11 at 8.45.56 PMNormally, when we see disputes over fraud allegations, it’s one author accusing another — but an unusual case at Cell has recently crossed our desk.

The journal has flagged a paper after an author confessed to committing fraud himself — but the corresponding author is disputing that confession, citing concerns about the confessor’s “motives and credibility.”

Independent labs are repeating the experiments to determine if the third author on the paper did, as he so claims, manipulate experiments. In the meantime, Cell and Molecular Cell have issued expressions of concern (EOCs) for two papers on which Yao-Yun Liang was a co-author. The notices cite an inquiry at Baylor College of Medicine, where the work was done, which was inconclusive, and recommended the journals take no action about the papers.

The EOCs are pretty much the same (both journals are published by Cell Press). Here’s the EOC that appears on “PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling,” published in 2006 by Cell and cited 251 times, according to Thomson Reuters Web of Science:

Continue reading Cell Press flags two papers after author confesses to fraud

Poll: Should co-authors of a scientific paper be allowed to change their minds?

lancetSince we reported Friday that multiple authors had asked to remove their names from a high-profile 2011 Lancet paper about a risky transplant surgery, a few readers have wondered: Should this be allowed?

To recap: The same day the journal announced it was tagging the controversial paper with an expression of concern, it issued a new erratum about the paper, removing three author names (one had already asked to be removed earlier). The highly cited paper has been under scrutiny ever since the last author, Paolo Macchiarini, has been facing allegations of misconduct, which most recently led to Macchiarini’s dismissal from the Karolinska Institutet. (Here’s our timeline of events to keep you abreast.)

It’s not surprising that a few of Macchiarini’s co-authors would want to distance themselves from this ever-expanding scandal, but should authors who originally signed onto a paper be able to change their minds? Let us know in our poll, below. Continue reading Poll: Should co-authors of a scientific paper be allowed to change their minds?

Concerns attached to three more papers by retraction-laden management researcher

Fred Walumbwa
Fred Walumbwa

Fred Walumbwa, a management researcher with eight seven retractions, has received three expressions of concern from two journals after he failed to provide raw data following an investigation into potential errors.

In the past, Walumbwa has said he only keeps data until his papers are published, but a lack of raw data has become a common theme in his notices, which now also include four corrections, and one other EOC (making a new total of four). There are no standard rules about how long to store raw data, but one journal that issued two of the new EOCs has since updated its submission policy to require that authors keep data for at least five years.

Walumbwa currently works at Florida International University. When concerns about the statistics were raised about five of his papers in Personnel Psychology, the journal conducted an investigation that led to flagging two of those articles, the expression of concern explains:

Continue reading Concerns attached to three more papers by retraction-laden management researcher

Lawsuit couldn’t stop four retractions for diabetes researcher

Mario Saad
Mario Saad

Four expressions of concern in the journal Diabetes have turned into retractions for Mario Saad, a move which he had tried to stop with a lawsuit.

Last August, a judge dismissed Saad’s suit against the American Diabetes Association, which publishes Diabetes, concluding that the expressions of concerns on the papers were not defamation, but part of an “ongoing scientific discourse.” Now, after an investigation at the University of Campinas in Brazil, where Saad is based, and an assessment from an ADA ethics panel (which overturned some of Unicamp’s recommendations), the journal has added to that discourse by turning the EOCs into retractions — and flagging two more of Saad’s papers with EOCs.

Together, the retracted papers have been cited more than 600 times.

As the retraction notes explain, Continue reading Lawsuit couldn’t stop four retractions for diabetes researcher

Firefly paper flagged following Queensland investigation

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A BMC journal has added an expression of concern to a paper on firefly genes after a University of Queensland investigation determined a table should be credited to a different source.

According to a representative of the university, the investigation found no evidence of misconduct. The university submitted an erratum that the journal chose not to publish; in the EOC note, the journal says the wording of the erratum is “under dispute.”

The erratum submitted to the journal specifies that the table should be attributed to former UQ biologist Robert Birch, who was not an author on the paper. The investigation concluded that the authors had not committed misconduct and “acted in good faith” in using the table, Anton Middelberg, University of Queensland Pro-Vice-Chancellor told us.

The paper, “Synthetic versions of firefly luciferase and Renilla luciferase reporter genes that resist transgene silencing in sugarcane, published in BMC Plant Biology, has been cited twice, according to Thomson Scientific’s Web of Knowledge.

Here’s the expression of concern:

Continue reading Firefly paper flagged following Queensland investigation

JACS imaging paper “under editorial review”

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The Journal of the American Chemical Society has issued an expression of concern over “the presentation of results” in a 2014 paper about a new probe for use in imaging.

We haven’t heard back from the journal nor the authors of the paper, so there’s not much we can officially say about what the journal is investigating.

Here’s the text from the expression of concern:
 Continue reading JACS imaging paper “under editorial review”

After hesitating, Science retracts chemistry paper against authors’ wishes

F1.mediumToday, Science has retracted a 2004 paper that’s been under scrutiny for years, despite the authors’ objections.

This paper has a long backstory: Recently, a report from the National Science Foundation’s Office of Inspector General surfaced that announced the agency had cut off the authors from funding. Last month, editor Marcia McNutt told us that the journal planned to retract the paper as soon as possible. Then, on January 21st, “just as we were going to press with the retraction,” said McNutt, the authors submitted a correction, which Science wanted to take some time to consider.

Now, the paper has a retraction note, against the wishes of authors Bruce Eaton and Dan Feldheim, currently at the University of Colorado.

Here it is the retraction note:

Continue reading After hesitating, Science retracts chemistry paper against authors’ wishes

Investigation of undisclosed conflicts in catheter paper uncovers flawed data, too

cov150hAn investigation into a paper that compared infection rates from different types of central lines started with an allegation about a failure to disclose a conflict of interest, and ended up concluding that the science in the paper was flawed.

The 2013 paper — now retracted by the American Journal of Infection Control — suggested a particular kind of connector between the catheter and the patient could reduce some of the notoriously deadly bloodstream infections associated with the procedure, according to a press release that publicized the work. But last year, the journal issued an expression of concern for the paper, noting there were questions about the data. The retraction note reveals an investigation at Georgia Regents University — now known as Augusta University — started looking into undisclosed conflicts of interest in the paper, and ultimately concluded the science was flawed.

Here’s the retraction note, published in the January 1st 2016 issue of the journal, for “Comparison of central line-associated bloodstream infection rates when changing to a zero fluid displacement intravenous needleless connector in acute care settings”

Continue reading Investigation of undisclosed conflicts in catheter paper uncovers flawed data, too

Following an earlier investigation, GW biologist earns two expressions of concern

3.cover (1)The Journal of Biological Chemistry has flagged two papers by a George Washington University cancer biologist with expressions of concern, following an investigation completed by the university in 2014.

The notes contain little specific information; all we know is that there are questions about the data and conclusions in the papers.

The last author on both papers is Rakesh Kumar, who adds these EoCs to a count that includes, according to our records, three retractions and five corrections. Plus an $8 million lawsuit against his employer for emotional distress when they put him on leave from his position as department chair.

The studies — “Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator” and “Regulation of NF-B circuitry by a component of the nucleosome remodeling and deacetylase complex controls inflammatory response homeostasis” — have been cited 22 times and 33 times respectively, according to Thomson Scientific’s Web of Knowledge.

The expression of concern is the same for both papers — and matches others that we’ve seen from JBC:

Continue reading Following an earlier investigation, GW biologist earns two expressions of concern