Category: data issues

Tomato study didn’t get co-author okays, includes unreliable data

scientia-horticulturaeA journal has retracted a paper examining the traits of drought-resistant tomatoes after an investigation at the first author’s institution in Italy found a number of problems.

For starters, the first author — Maria Riccardi of the National Research Council of Italy-Institute for Agricultural and Forest Systems in the Mediterranean (CNR-ISAFOM) in Ercolano, Naples, Italy — apparently submitted the paper without consulting the study’s four other listed co-authors. What’s more, according to the retraction notice in Scientia Horticulturae, the paper’s description of the experiment “does not reflect the real conditions under which the data was collected,” rendering the findings invalid.  

Riccardo d’Andria, CNR-ISAFOM’s former director who conducted an investigation into the case, said Continue reading Tomato study didn’t get co-author okays, includes unreliable data

Authors pull two papers about faulty glucose meters after industry prompts

4.coverTwo papers evaluating glucose meters — used by diabetics to monitor blood sugar levels — suggested that a couple of the devices don’t work as well as they should. Perhaps unsurprisingly, the companies that sell those meters objected to how the studies were conducted. By all accounts, the companies appear to be justified in their complaints.

In both cases, researchers used blood drawn from veins to test the meters. But manufacturers of the WaveSense JAZZ and GlucoRx glucose meters said their devices are designed to work with fresh blood from a finger-prick. Both papers have now been retracted.

The retraction notice for “Technical and clinical accuracy of five blood glucose meters: clinical impact assessment using error grid analysis and insulin sliding scales,” published in 2015 in the Journal of Clinical Pathology, hints at the issue:

Continue reading Authors pull two papers about faulty glucose meters after industry prompts

Analysis casts doubt on bone researcher’s body of work

19-coverA new analysis of more than 30 clinical trials co-authored by a bone researcher based in Japan is casting doubt on the legitimacy of the findings.

Yoshihiro Sato, based at Mitate Hospital, has already retracted 12 papers, for reasons ranging from data problems, to including co-authors without their consent, to self-plagiarism. Most of these retracted papers are included in the analysis in the journal Neurology, which concluded that Sato’s 33 randomized clinical trials exhibited patterns that suggest systematic problems with the results.

Other researchers have used similar approaches to analyze a researcher’s body of work — notably, when John Carlisle applied statistical tools to uncover problems in the research of notorious fraudster Yoshitaka Fujii, and Uri Simonsohn, who sniffed out problems with the work of social psychologist  Dirk Smeesters.

Author Mark Bolland of the University of Auckland told us he was surprised by his findings: Continue reading Analysis casts doubt on bone researcher’s body of work

Genetics study flagged for reliability issues by Frontiers journal

frontiers-in-geneticsA genetics journal has issued an expression of concern (EOC) for a study after an investigation by its chief editors.

According to the notice in Frontiers in Genetics, the authors of the paper — based at Hokkaido University in Sapporo, Japan — are conducting further experiments to resolve the issues raised by the journal’s investigation.

In February, the same paper received a corrigendum due to errors in the assembly of one of the figures.

Here’s the EOC, issued earlier this week: Continue reading Genetics study flagged for reliability issues by Frontiers journal

Authors retract third cancer paper for missing original data

international-journal-of-oncologyResearchers have retracted their third paper due to missing original data, following an investigation at their former institution in New York.

We’ve previously reported on two retractions of papers co-authored by Bhagavathi Narayanan and Narayanan K. Narayanan, previously based at the New York University (NYU) School of Medicine. The studies were pulled when the pair couldn’t provide original images to investigators at NYU School of Medicine. One author has blamed the lack of original data on the abrupt closure of her previous institution in 2004, after it allegedly misspent millions in federal grants. 

However, the latest retraction affects a paper published eight years later in the International Journal of Oncology. Its coauthors include Bhagavathi Narayanan, Narayanan K. Narayanan and Rajkishen Narayanan; we haven’t been able to uncover if there is a relation between them.

A spokesperson for the NYU School of Medicine sent us this statement: Continue reading Authors retract third cancer paper for missing original data

Cancer paper flagged due to “credible” concerns over its reliability, journal says

rsc-advancesA journal has issued an expression of concern (EOC) for a cancer study after the publisher received what it called a “credible” tip that its results may not be reliable.

According to the EOC, published in RSC Advances, the paper is now under investigation.

Here’s the EOC for “Filled and peptide-modified single-walled carbon nanotubes: synthesis, characterization, and in vitro test for cancer cell targeting:” Continue reading Cancer paper flagged due to “credible” concerns over its reliability, journal says

Despite retraction, antipsychotics still effective, safe for dementia, says author

alzheimers-research-and-therapyResearchers have retracted a systematic review that suggested that antipsychotic drugs are effective and safe for patients with symptoms of dementia — but claim their re-analysis of the updated data still comes to the same conclusions.

According to the retraction notice in Alzheimer’s Research and Therapy, some participants were incorrectly included twice in the meta-analysis. 

The corresponding authors recently lost another paper for an entirely different reason — earlier this year, we reported on a retraction in Annals of Neurology for Jin-Tai Yu and Lan Tan, affiliated with the Ocean University of China, Qingdao University, and Nanjing Medical University in China. The authors pulled that paper after appearing to pass off others’ data as their own.

Here’s the retraction notice for the review, issued earlier this year: Continue reading Despite retraction, antipsychotics still effective, safe for dementia, says author

Macchiarini paper in Nature journal earns expression of concern for data questions

nature-communications-228x300Nature Communications has issued an expression of concern for a 2014 paper by beleaguered surgeon Paolo Macchiarini, citing concerns over whether the paper accurately reports the experiments that were carried out.

According to the notice, Macchiarini, a former rising star in the field of transplant medicine, agrees with the expression of concern. Three of his 22 co-authors have objected.

“Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats” describes transplanting an esophagus into rats that was seeded with their own stem cells, and notes that all animals survived the study period (14 days), and gained more weight than rats given a placebo operation. It’s a topic Macchiarini has made famous, as the first surgeon to perform a similar procedure with a human tracheal transplant. But he’s faced charges of misconduct in the last few years, resulting in his dismissal from Karolinska Institutet (KI).

Here’s the text of the notice, scheduled to go live at 10 a.m. UK time today: Continue reading Macchiarini paper in Nature journal earns expression of concern for data questions

Authors retract (and replace) cardiac rehab study in JAMA journal

jama-internal-medicine

Researchers have retracted and replaced a 2014 paper in JAMA Internal Medicine after realizing a number of errors had affected the findings.

The authors note the mistakes do not have a significant impact on the overall proportion of heart patients who participated in cardiac rehab. However, a number of findings were affected, such as the difference in participation in cardiac rehab defined by race, and how the overall participation has changed throughout the years.

Therefore, JAMA Internal Medicine has published a lengthy notice of retraction and replacement, which explains the errors made in the original paper, and updated the first paper with a new version of the study.

The retraction and replacement notice, issued this week, starts: Continue reading Authors retract (and replace) cardiac rehab study in JAMA journal

Yes, “power pose” study is flawed, but shouldn’t be retracted, says one author

psychological-scienceAfter the first author of a debated study about the benefits of positioning your body in an assertive ways — the so-called “power pose” — posted her concerns about the research, she has told us she does not believe the paper should be retracted.

As reported by New York magazine, late last night, the first author of a 2010 paper in Psychological Science posted a statement saying she no longer believes the effects of the “power pose” are real.

We contacted Dana Carney, now based at the University of California, Berkeley, to ask if she thought the next step would be to retract the paper. She told us: Continue reading Yes, “power pose” study is flawed, but shouldn’t be retracted, says one author