About a month ago, the New England Journal of Medicine told us that they didn’t “have any plans” to retract a paper by Anil Potti. Apparently, they’ve changed their minds.
Today, they posted this retraction notice: Continue reading NEJM retracts Potti paper
Since we first wrote about the travails of Spirocor’s bedside, noninvasive test for coronary artery disease, we’ve been trying, without much success, to find out more information.
But as they say about every dog, our day has come.
As we initially reported, Ron Waksman, a prominent Washington, D.C. cardiologist and editor-in-chief of Cardiovascular and Revascularization Medicine, was first author of one of two papers about the Spirocor technology that were published in 2010. The other, by Shiyovich, et al, was retracted earlier this month by the American Journal of the Medical Sciences, which triggered our interest in this case.
At the time, we couldn’t find any evidence that Waksman’s article had been retracted, and Waksman has not responded to multiple requests for comment. Today we spoke with Kate Coons, the journal’s managing editor, who told us that the authors had sought a retraction for the article, “An innovative noninvasive respiratory stress test indicates significant coronary artery disease,” in December, and that it had posted one on its website on Jan. 6 of this year. It will be in print in an upcoming issue.
The notice is not available on Medline, but it can be found on ScienceDirect: Continue reading More on SPIROCOR noninvasive heart disease test: Second retraction (in fact the first) says little
A retraction in an obscure journal. An equally obscure retraction notice. An Israeli company with no web presence. Conflicts of interest involving authors and editors.
That’s what we’ve uncovered so far after noticing the other day that the American Journal of the Medical Sciences (AJMS) had retracted a May 2010 article by a group of Israeli heart doctors led by Arthur Shiyovich, of Barzilai Medical Center in Ashkelon.
The paper described promising results in a study of a new test for diagnosing coronary artery disease at the bedside by measuring aspects of a patient’s pulse at the fingertip.
As AJMS editor David Ploth told us, the approach had seemed “kind of innovative” to him, so he’d accepted the manuscript: “It seemed like it might have some applicability.”
Ploth was therefore surprised sometime later to receive a letter from the authors requesting that the journal retract their paper. According to the journal: Continue reading Tangled leads: Cardiac study retraction reveals a company’s stopped trials, and lots of questions
With the third retraction of a paper by Anil Potti this weekend, plus details of various investigations dribbling out, we decided to check in with the world’s two leading medical journals about whether they planned to retract the papers of Potti’s they’d published.
JAMA published two papers by Potti and colleagues: One, “Gene Expression Signatures, Clinicopathological Features, and Individualized Therapy in Breast Cancer,” appeared in 2008. It has been cited 51 times, according to Thomson Scientific’s Web of Knowledge, and was the subject of two letters. In one, a correspondent expressed concerns about the lack of information in the study about Continue reading No Potti retractions on the horizon from JAMA, NEJM
Early in December, as the house of cards that is Anil Potti‘s publication record started to really collapse, we called attention to a paper in The Lancet Oncology that had already been the subject of a correction and Expression of Concern in July of last year. Today, the journal officially retracted the paper, “Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial.” The paper was cited more than 100 times, according to Google Scholar.
The retraction notice: Continue reading Lancet Oncology retracts previously questioned Anil Potti paper
A quick post this Sunday morning to draw your attention to two must-read items for anyone interested in the Anil Potti case or in how one goes about checking data. (A second paper by Potti et al was officially retracted on Friday.)
First, a terrific profile of Joyce Shoffner in the Charlotte News & Observer. Shoffner
was one of 110 Duke patients enrolled in three clinical trials based on the research of Dr. Anil Potti, who resigned in November as an associate professor at Duke.
Here at Retraction Watch, we obviously think all retractions are worth following. But we hope this story will convince those who shrug and say such items are inside baseball, or “none of your damn business,” that they need to re-evaluate their positions. This is where the rubber hits the road: Continue reading Update on Anil Potti: A patient in a trial based on retracted research speaks out; Baggerly on how to prevent the next fiasco
Nature Medicine has retracted a paper that Anil Potti’s co-author, Joseph Nevins, requested be withdrawn in November.
This is the second retraction of a paper by Potti, who resigned from his post at Duke in November in the midst of an investigation into scientific misconduct. The first retraction was in the Journal of Clinical Oncology.
According to the Nature Medicine retraction notice: Continue reading Nature Medicine makes it official, retracting Anil Potti paper
Yesterday, we reported on the retraction of a 2004 study in the Annals of Thoracic Surgery. As we noted, the notice’s language was, um, fuzzy, referring vaguely to
an investigation by the University of Florida, which uncovered instances of repetitious, tabulated data from previously published studies.
Today, we are slightly more clear, although what we really got was an earful of other language.
We had the pleasure of speaking this morning with L. Henry Edmunds, Jr., the long-time editor of the Annals of Thoracic Surgery, who gave us a better sense of why his retraction notice was so delicately worded. Edmunds, responding to question of why the letter didn’t say more about the matter:
It’s none of your damn business.
Ranting against “journalists and bloggists,” Edmunds, a cardiac surgeon at the University of Pennsylvania, said the purpose of the retraction notice was merely Continue reading Why was that paper retracted? Editor to Retraction Watch: “It’s none of your damn business”
The Annals of Thoracic Surgery has retracted a 2004 article by a group of Florida researchers who were found by their university to have misrepresented the provenance of their data.
If that construction sounds a trifle precious (er, weasel-y), that’s because the retraction notice does, too: Continue reading Thoracic surgery journal retracts hypertension study marred by troubled data
It’s fair to say that we haven’t heard the last of Anil Potti, the Duke cancer researcher who resigned last month following revelations that he had faked some of his results. Duke is still investigating the situation, and has also asked the Institute of Medicine to conduct its own study into the case and its ramifications.
This week, we may find out whether Nature Medicine will retract a paper that Joseph Nevins, one of Potti’s co-authors, asked the journal to withdraw last month. We’re also keeping an eye on two other papers that have already been the subject of increased scrutiny: Continue reading More on Anil Potti: Two other papers worth keeping an eye on