A new reproducibility fix? Get your work checked before it’s published

Jeffrey Mogil
Malcolm Macleod

Most researchers by now recognize there’s a reproducibility crisis facing science. But what to do about it? Today in Nature, Jeffrey S. Mogil at McGill University and Malcolm R. Macleod at the University of Edinburgh propose a new approach: Restructure the reporting of preclinical research to include an extra “confirmatory study” performed by an independent lab, which verifies the findings before they are published. We spoke with them about how this could work.

Retraction Watch: You’re proposing to restructure animal studies of new therapies or ways to prevent disease. Can you explain what this new type of study should look like, and how researchers will execute it?

Continue reading A new reproducibility fix? Get your work checked before it’s published

“An example for all authors to uphold:” Researcher logs 5 corrections

A scientist in Ireland has corrected five of his papers in a single journal dating back more than a decade, after image-related problems were brought to his attention.

Four of the newly corrected papers have a common last and corresponding author: Luke O’Neill of Trinity College Dublin in the Republic of Ireland. O’Neill is also a co-author of the remaining paper that was fixed. O’Neill told us the mistakes were a “bit sloppy,” noting that he takes responsibility for the errors in the four papers on which he is last author.

O’Neill forwarded Retraction Watch a comment he received from Kaoru Sakabe — data integrity manager at the American Society for Biochemistry and Molecular Biology (which publishes The Journal of Biological Chemistry (JBC)) — that reads:

Continue reading “An example for all authors to uphold:” Researcher logs 5 corrections

Dear Peer Reviewer: Could you also replicate the experiments? Thanks

via the University of St Andrews

As if peer reviewers weren’t overburdened enough, imagine if journals asked them to also independently replicate the experiments they were reviewing? True, replication is a big problem — and always has been. At the November 2016 SpotOn conference in London, UK historian Noah Moxham of the University of St Andrews in Scotland mentioned that, in the past, some peer reviewers did replicate experiments. We asked him to expand on the phenomenon here.

Retraction Watch: During what periods in history did peer reviewers repeat experiments? And how common was the practice? Continue reading Dear Peer Reviewer: Could you also replicate the experiments? Thanks

High-profile Science paper retracted for misconduct

Science has retracted a high-profile immunology paper after a probe concluded the corresponding author had committed misconduct.

The paper — which initially caught media attention for suggesting a protein could help boost the immune system’s ability to fight off tumors — has been under a cloud of suspicion since last year, when the journal tagged it with an expression of concern, citing a university investigation.

That investigation — at Imperial College London — has concluded that the paper contained problematic figures that were the result of research misconduct. All were prepared by last and corresponding author Philip Ashton-Rickardt, who took full responsibility. Even though the paper was published in 2015, some original blots and accompanying details have disappeared.

Today, the journal released a retraction notice: Continue reading High-profile Science paper retracted for misconduct

Authors retract paper linking nuclear power to slow action on climate change

climate-policyDo pro-nuclear energy countries act more slowly to curb the effects of climate change? That’s what a paper published in July in the journal Climate Policy claimed. But the hotly debated study was retracted last week after the authors came to understand that it included serious errors.

An August 22 press release about the original study has been retracted by the University of Sussex, and no longer appears on ScienceDaily. An archived version notes:   Continue reading Authors retract paper linking nuclear power to slow action on climate change

Authors pull two papers about faulty glucose meters after industry prompts

4.coverTwo papers evaluating glucose meters — used by diabetics to monitor blood sugar levels — suggested that a couple of the devices don’t work as well as they should. Perhaps unsurprisingly, the companies that sell those meters objected to how the studies were conducted. By all accounts, the companies appear to be justified in their complaints.

In both cases, researchers used blood drawn from veins to test the meters. But manufacturers of the WaveSense JAZZ and GlucoRx glucose meters said their devices are designed to work with fresh blood from a finger-prick. Both papers have now been retracted.

The retraction notice for “Technical and clinical accuracy of five blood glucose meters: clinical impact assessment using error grid analysis and insulin sliding scales,” published in 2015 in the Journal of Clinical Pathology, hints at the issue:

Continue reading Authors pull two papers about faulty glucose meters after industry prompts

Prominent researcher in Scotland resigns after misconduct finding upheld

robert-ryan_0
Robert Ryan

A rising star in the field of infectious disease has resigned from the University of Dundee in Scotland after the university upheld the findings of an investigation concluding that he committed misconduct.

Earlier this year, Robert Ryan was suspended amidst the investigation, which focused on data doctoring in several publications. We’ve now been forwarded an internal email from Julian Blow, dean of the School of Life Sciences, which alerts staff that Ryan has resigned, and the institution has upheld its finding of misconduct, despite Ryan’s appeal.

In 2015, Ryan was selected to be an EMBO Young Investigator; yesterday, EMBO announced that it had withdrawn him from the program.

Blow’s email to staff, dated November 9, states:

Continue reading Prominent researcher in Scotland resigns after misconduct finding upheld

Physics journal retracts paper without alerting author

annals-of-physics

An Elsevier journal has angered an author by removing his study without telling him.

After spending months asking the journal why it removed the paper — about a heavily debated theorem in physics — and getting no response, the author threatened to seek damages from the journal and publisher for “permanently stigmatizing” his work. Yesterday, an Elsevier representative told the author what happened: Experts told the journal the paper had a major mistake, so the journal decided to withdraw the study, but failed to tell the author due to an “internal error.”

That explanation didn’t satisfy study author Joy Christian, scientific director of the Einstein Centre for Local-Realistic Physics in Oxford, UK, who has demanded the journal either republish the article or remove it and return the copyright to him, or he will pursue legal action.

Here’s the cryptic publisher’s note for “Local causality in a Friedmann–Robertson–Walker spacetime:” Continue reading Physics journal retracts paper without alerting author

Error in one line of code sinks cancer study

journl-of-clinical-oncologyAuthors of a 2016 cancer paper have retracted it after finding an error in one line of code in the program used to calculate some of the results.

Sarah Darby, last author of the now-retracted paper from the University of Oxford, UK, told Retraction Watch that the mistake was made by a doctoral student. When the error was realized, Darby said, she contacted the Journal of Clinical Oncology (JCO), explained the issue, and asked whether they would prefer a retraction or a correction. JCO wanted a retraction, and she complied.

The journal allowed the authors to publish a correspondence article outlining their new results.

Here’s the lengthy retraction notice, published online last month: Continue reading Error in one line of code sinks cancer study

Despite apology, bagpipes study not slated for retraction

Thorax

It’s not often that a paper elicits an apology — but that’s just what happened when family members first learned a bagpipe musician died from inhaling mold and fungi from a case study reported in a journal. The hospital has since apologized; the journal, however, told us it is not planning to issue a retraction.

The University Hospital of South Manchester NHS Foundation Trust in Wythenshawe, UK, has apologized and launched an internal investigation into the case report after the family’s distress was extensively covered by the UK’s mainstream media, such as The BBC, The Independent, The Daily Mail, and The Telegraph.

There seem to be conflicting accounts over whether any consent was obtained to publish the report. The Thorax paper says the patient gave consent, and according to Gisli Jenkins, co-editor-in-chief of the journal and a professor of experimental medicine at Nottingham University in the UK, consent was sought from the family. But the patient’s daughter told us that neither the next of kin nor the patient were approached for consent. 

The release of the report on August 22 was “completely unethical,” said Erin Tabinor, daughter of musician Bruce Campbell and a makeup artist in Liverpool, UK. Tabinor told us that the family wasn’t aware that playing bagpipes was the cause of Campbell’s death: Continue reading Despite apology, bagpipes study not slated for retraction