Does this scientific image look familiar? It’s from a catalog

cover (4)There’s something strange about a 2008 paper on the role of nicotine receptors in promoting lung cancer: One of the western blot analyses looks like a version of an image from a commercial catalog.

A commenter on PubPeer pointed out the similarities between an image in “Role of α7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation,” which was published in Cell Proliferation, and one used to promote an enzyme sold by Cell Signaling Technology.

Unfortunately, if the images are indeed the same, we can’t tell for certain who copied from whom. But a representative of the company told us it generates its own images, and this one was likely created before the paper was published. The last author — for whom we’ve found three other retractions — denied that the paper copied the image.

Here’s the panel from the paper, which was published in 2008: Continue reading Does this scientific image look familiar? It’s from a catalog

Son sees dead father in case report, requests retraction

ijscrAuthors have retracted a case report describing a surgery to remove gallstones in a patient with Crohn’s disease after learning they’d mixed up two cases, and instead reported on a patient who had died 21 days after the procedure.

We were alerted to this story by La Repubblica, and contacted by the son of the patient (who asked not to be named, for privacy reasons). He told us he found the study and asked the journal to retract it:

…I can say that it was absolutely devastating to realise that the pictures I was looking at were from the surgery that led to the death of my father. It is something that gives me a lot of sorrow thinking that the man in that picture with the open belly was him, when he was fighting for his life. I asked the rest of my family not to see them to avoid them the same shock.

Even before the retraction appeared, we received confirmation it was coming from Giuseppe Paolisso, the Principal of the School of Medicine at the Second University of Naples, where the authors are based: Continue reading Son sees dead father in case report, requests retraction

Another paper by GM researcher pulled over manipulation concerns

Screen Shot 2016-03-14 at 11.52.18 AMA researcher who published findings questioning the safety of genetically modified organisms has lost a second paper following concerns of image manipulation.

Last week, the journal animal retracted a 2010 paper by Federico Infascelli, an animal nutrition researcher at the University of Naples, which claimed to find modified genes in the milk and blood of goats who were fed genetically modified soybeans. The retraction stems from an investigation that concluded the authors likely manipulated images, according to the note. Earlier this year, another journal retracted one of Infascelli’s papers that contained a duplicated figure.

In February, Italian paper La Repubblica (which we read with Google Translate) reported that the university found problems in three of his articles and issued a warning.

Here’s the retraction note for “Fate of transgenic DNA and evaluation of metabolic effects in goats fed genetically modified soybean and in their offsprings:”

Continue reading Another paper by GM researcher pulled over manipulation concerns

Investigation leads to 5th retraction for drug researcher

Screen Shot 2016-01-26 at 6.05.21 PMA pharmaceutical researcher has received his fourth and fifth retractions for duplicating papers.

Last we saw Giuseppe Derosa on this blog, he was notching retractions after publishing results from the same clinical trial in six different papers; as part of that fallout, a journal has pulled a fourth paper associated with the trial.

Here’s the note for “Effects of an olmesartan/amlodipine fixed dose on blood pressure control, some adipocytokines and interleukins levels compared with olmesartan or amlodipine monotherapies,” which has been cited twice, according to Thomson Scientific’s Web of Knowledge:  Continue reading Investigation leads to 5th retraction for drug researcher

Paper claiming GMO dangers retracted amid allegations of data manipulation

FNS2015012717103119A nutrition journal is retracting a paper about potential dangers of eating food containing genetically modified organisms (GMOs) for duplicating a figure, as news stories from Italy are reporting accusations that the last author falsified some of his research.

In the paper, Federico Infascelli, an animal nutrition researcher at the University of Naples, and his colleagues showed modified genes could wind up in the blood and organs of baby goats whose mothers ate GM soybeans. According to our Google Translate version of an article by Italian newspaper La Repubblicaan investigation suggests that Infascelli has manipulated images to suggest GMOs are harmful. He could face fines and be suspended from the university.

La Repubblica reports that a committee appointed by the rector of the university, Gaetano Manfredi, found errors in Infascelli’s data that suggested he had manipulated the results to show GMOs were harmful.

One paper by Infascelli has been retracted from Food and Nutrition Science, Gamma-Glutamyl Transferase Activity in Kids Born from Goats Fed Genetically Modified Soybean.” The retraction note says the paper was pulled for duplication:

Continue reading Paper claiming GMO dangers retracted amid allegations of data manipulation

Cancer Cell paper under investigation following anonymous queries on PubPeer

cancer cell

A Cancer Cell paper that caused a flurry of activity on the website PubPeer is under investigation, after the last author announced on the site that he’d requested a correction from the journal.

The 2012 paper sparked a lively dialogue last month on the post-publication discussion site, as commenters questioned Western blot images in which some bands appeared to be duplicates. The last author responded, noting he had alerted the journal to a “mishap,” and a correction would be forthcoming. However, some commenters remained unsatisfied, and questioned why the correction was taking so long to appear, as well as the explanation for what went wrong.

A spokesman from Cancer Cell confirmed to us the paper is under investigation:

Continue reading Cancer Cell paper under investigation following anonymous queries on PubPeer

Authors retract abstract following misconduct by diabetes biotech

1Earlier this year, authors retracted a meeting abstract about a diabetes drug, following the revelation that the biotech that funded the trial committed misconduct.

The retraction was initiated by corresponding author Itamar Raz, at Hadassah Medical Center in Israel. The journal didn’t receive a response from any co-authors who were affiliated with the biotech company, Andromeda, so they were not included in the retraction process.

A few months after Hyperion Therapeutics acquired Andromeda’s diabetes drug DiaPep277, Hyperion announced it had evidence that some employees of Andromeda had “engaged in serious misconduct,” such as using un-blinded data and manipulating the analyses. Two relevant studies on the drug, designed to block the immune response that leads to type 1 diabetes, were retracted last year.

Here’s the retraction note for the abstract “Abstracts of the 50th Annual Meeting of the EASD, Vienna 2014. ‘Evaluation of DiaPep277® treatment in type 1 diabetes by integrated analysis,’” published in the May issue of the journal:

Continue reading Authors retract abstract following misconduct by diabetes biotech

Mystery: A bullet with no entry wound, in a paper with no spell check?

world emergency surgeryThe Patient, a 60-years old Caucasian male found unconscious in a trailer park of gypsies…”

So begins a strange — and apparently not copyedited — new case report in the World Journal of Emergency Surgery. The paper concerns a patient — perhaps we should call him Rasputin — who showed up with a bullet in his left lung but no entry wound that would explain its presence.

Naturally, the authors draw the obvious conclusions:

Continue reading Mystery: A bullet with no entry wound, in a paper with no spell check?

Mol bio paper pulled by PLOS following investigation into figures

Screen Shot 2015-11-17 at 11.58.47 AMPLOS Biology has retracted a paper about the molecular details of β-catenin expression following an investigation by the first author’s institution in Italy.

The investigation, by the Istituto Nazionale per la Ricerca sul Cancro, found that there were multiple “figure anomalies.” According to the note:

An explanation of inadvertent error was given for some of the issues identified, while for two issues, a satisfactory explanation could not be provided.

First author Roberto Gherzi says none of his co-authors helped prepare the figures. The authors maintain that the conclusions are unaffected, but that assurance wasn’t enough for the journal. Here’s more from the lengthy retraction note, which provides some backstory on the “serious concerns” regarding the data:

Continue reading Mol bio paper pulled by PLOS following investigation into figures

Serial plagiarist’s retractions upped to 14

We’ve done some digging, run the numbers, and present to you a new member of our leaderbcov200hoard: orthopedic researcher Bernardino Saccomanni. Nine newly unearthed retractions of his make for a total of 14.

We first reported on Saccomanni’s work back in 2011, and identified him as a “serial plagiarist.” In the years since, he’s continued to rack up retractions for papers on the likes of ligament reconstruction and shoulder pain. On every paper, he is listed as the sole author.

Bernardino Saccomanni’s most recently listed affiliation on the papers is “Ambulatorio di Ortopedia, via della Conciliazione.” He sometimes also lists his affiliation as Gabriele D’ Annunzio University Chieti, even though, as we learned a few years ago, he hasn’t worked there for many years.

There’s a lot to cover here, so stick with us:

1) First up, “A new test for acromio-clavicolar pathology” was published in the Journal of Clinical Orthopedics and Trauma and cited zero times according to Thomson Scientific’s Web of Knowledge. Here’s the retraction note:

Continue reading Serial plagiarist’s retractions upped to 14