Author: Megan Scudellari

Gut paper retracted after university review says “figures cannot be validated by original data”

IBDA biologist at Case Western Reserve University School of Medicine in Ohio has retracted a paper from Inflammatory Bowel Diseases after a university review found the figures within it could not be “validated by original data.”

The 2010 paper, “Elevated IL-13Rα2 in intestinal epithelial cells from ulcerative colitis or colorectal cancer initiates MAPK pathway,” concerns the elevated expression and role of an inflammatory protein in colon cancer cells.

According to the notice, corresponding author and biologist Alan Levine — who recently received a $3.9 million Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse — requested the retraction.

Here’s the full notice: Continue reading Gut paper retracted after university review says “figures cannot be validated by original data”

JBC retraction on neuron development marks second for two biologists

JBCTwo biologists have retracted a second paper on the development of neurons, but that’s about all we know.

The 2007 paper from the Journal of Biological Chemistry, “The Interaction of mPar3 with the Ubiquitin Ligase Smurf2 Is Required for the Establishment of Neuronal Polarity,” concerns the role of a protein, mPar3, in neuron development. It has been cited 29 times, according to Thomson Scientific’s Web of Knowledge.

We don’t know why this one was retracted, because JBC (as usual) offered no explanation in its retraction note:

Continue reading JBC retraction on neuron development marks second for two biologists

Two crystallography papers break apart for “trivial errors,” says author

ACBiophysicists in India have retracted two crystallography papers describing protein binding sites following “concerns,” according to one retraction note.

The last author on both papers, however, told us he believed the retractions were the result of “trivial errors.” Although one journal praised him in its retraction note for his “positive engagement,” he said the process left him feeling “disgusted.”

One paper, “Structural Studies on Molecular Interactions between Camel Peptidoglycan Recognition Protein, CPGRP-S, and Peptidoglycan Moieties N-Acetylglucosamine and N-Acetylmuramic Acid,” was withdrawn from the Journal of Biological Chemistry in August 2014.

The second, “Mode of binding of the antithyroid drug propylthiouracil to mammalian haem peroxidases,” was retracted from Acta Crystallographica Section F this month. Here’s the retraction notice: Continue reading Two crystallography papers break apart for “trivial errors,” says author

Accounting professor notches 30 (!) retractions after misconduct finding

James Hunton, via Bentley University
James Hunton, via Bentley University

It began with a retraction due to a “misstatement” in November 2012, which led to an investigation that found the first author, James E. Hunton, guilty of misconduct.  Now, the floodgates have opened, and Hunton has 31 retractions under his belt, making him the newest addition to the Retraction Watch leaderboard.

A month after the first retraction in 2012, Hunton resigned from his accounting professorship at Bentley University, citing family and health concerns.

Then, in 2014, a university investigation concluded that Hunton fabricated data in two papers and may have destroyed evidence. The first paper was the one retracted from Accounting Review for a misstatement; the second was retracted from Contemporary Accounting Research in December 2014. Even though the investigation centered around two publications, the university suggested more may be affected:

Continue reading Accounting professor notches 30 (!) retractions after misconduct finding

A tale of two journals: Elsevier retracts paper after publishing it in the wrong journal

EMIf you happen to pick up this month’s issue of Economic Modelling, there’s a little surprise on page 307—blank pages. Publisher Elsevier has retracted a paper from that space because it “inadvertently published” the paper in the journal. In fact, Elsevier meant to include the paper in the pages of its other journal, Energy Economics.

The paper, “An Approach to Computing Marginal Land-Use Change Carbon Intensities for Bioenergy in Policy Applications,” is most assuredly not about economic modeling. Rather, it describes an approach for assessing carbon emissions from the production of bioenergy crops.

Here’s the retraction notice: Continue reading A tale of two journals: Elsevier retracts paper after publishing it in the wrong journal

Food fight: Animal nutrition author disputes two retractions

LSA pair of animal nutrition researchers in India have now had a second paper on the nutritional value of a fungal treatment for wheat straw retracted, and one of the authors is very unhappy about it.

M.S. Mahesh of the National Dairy Research Institute at Deemed University claims a co-author issued “abusive letters” to an editor of the journal where the first paper was retracted (which said co-author denies), and that editors responsible for the second retraction removed the paper “unscientifically and unethically.”

The second paper, in Livestock Science, describes the treatment of wheat straw, a wheat by-product, with a fungus in an effort to improve the nutritional worth of the straw. It has a similar title, subject, and conclusions to those of a 2013 paper from the journal Tropical Animal Health and Production, which was retracted because the authors “had no permission to use the data presented in the Table 1.”

We described that earlier retraction from TAHP, and the similarity with this most recently retracted paper, in a post from early last year.

Here is the LS retraction notice for “Nutritional evaluation of wheat straw treated with white-rot fungus Crinipellis sp. RCK-SC in Sahiwal calves”: Continue reading Food fight: Animal nutrition author disputes two retractions

Columbia biologists “deeply regret” Nature retraction, after postdoc faked 74 panels in 3 papers

natureA team of Columbia University biologists has retracted a 2013 Nature paper on the molecular pathways underlying Alzheimer’s disease, the second retraction from the group after a postdoc faked data.

An April report from the Office of Research Integrity (ORI) found the a first author, former Columbia postdoc Ryousuke Fujita, responsible for “knowingly and intentionally fabricating and falsifying research in seventy-four (74) panels” in three papers: a 2011 Cell paper retracted in 2014, an unpublished manuscript, and this now-retracted Nature paper, “Integrative genomics identifies APOE e4 effectors in Alzheimer’s disease.”

The paper was touted in a Columbia University Medical Center press release as identifying “key molecular pathways” leading to late-onset Alzheimer’s disease. The paper fingered two potential molecular drug targets, as well.

Here is the full retraction notice: Continue reading Columbia biologists “deeply regret” Nature retraction, after postdoc faked 74 panels in 3 papers

“Evidence of data duplication” infects lung inflammation paper from Harvard and Yale

IAIA team of Harvard and Yale biologists have retracted an Infection and Immunity paper due to data duplication.

After the duplication came to light, the erroneous figures were corrected using original data, but the results affected “some of the manuscript’s conclusions.” An ethics panel subsequently recommended retraction, according to the journal, and the authors agreed.

The paper, “NOD2 Signaling Contributes to Host Defense in the Lungs against Escherichia coli Infection,” analyzed the role of the gene NOD2 in the lung inflammatory response against the bacteria Escherichia coli. It has been cited by 15 other papers, according to Thomson Scientific’s Web of Knowledge.

Figure 2B of the paper was previously corrected in 2012, but the retraction is for data duplication in figures 5F and 6A. Here’s the full retraction note: Continue reading “Evidence of data duplication” infects lung inflammation paper from Harvard and Yale

“Significant concerns” and formal investigation unwind Nature Nanotech sequencing paper

NatureNanoFollowing “significant concerns” raised by outside researchers and a formal university investigation, a group of authors in Taiwan has retracted a Nature Nanotechnology paper on DNA sequencing after they “could not reproduce the results of the work,” or even provide “a complete set of raw data for the original experiments.”

The paper, “DNA sequencing using electrical conductance measurements of a DNA polymerase,” describes a technology to sequence single DNA molecules — a technique that the authors, all based at National Chiao Tung University in Taiwan, suggest could be used to “cheaply and quickly” sequence DNA.

Concerns about the paper’s data were first raised in May 2013 by the community, according to an editorial from the journal. Then, the journal asked the university to investigate, says “Notes on a retraction”: Continue reading “Significant concerns” and formal investigation unwind Nature Nanotech sequencing paper

“I hold my hands up”: PubPeer criticisms spark a biochemist’s offer to retract

MPIn a back-and-forth on PubPeer, a researcher appears to have offered to retract a paper after commenters challenged the use of identical control bands on a gel.

A person writing as Virginia Commonwealth University biochemist Paul Dent admitted the control bands of his 2007 Molecular Pharmacology paper, “Human Chorionic Gonadotropin Modulates Prostate Cancer Cell Survival after Irradiation or HMG CoA Reductase Inhibitor Treatment,” were duplicated “for comparison purposes,” but stated he was “in no way attempting to ‘intentionally manipulate the data.’”

In response, Dent appeared to offer to pull the paper, about using a hormone to help kill prostate cancer cells:

Continue reading “I hold my hands up”: PubPeer criticisms spark a biochemist’s offer to retract