“Most responsible course of action is to retract:” Duplicated images fell prostate cancer paper

International Journal of CancerA study on the cellular interactions underlying prostate cancer has been retracted after a whistleblower pointed out duplicated images in one of the paper’s figures that were “erroneously presented as unique.”

The International Journal of Cancer posted the notice in June. The authors backed the paper’s conclusions but agreed, “the most responsible course of action is to retract.”

The notice reads:

Continue reading “Most responsible course of action is to retract:” Duplicated images fell prostate cancer paper

Food article pulled when authors can’t serve up data

homeHeaderLogoImage_en_USAn article about a dietary plan to help people lose weight has been retracted after other researchers raised concerns, and the authors failed to provide the data that supported their findings.

The retraction is accompanied by a Letter to the Editor by a group of outside researchers — including David Allison at the University of Alabama at Birmingham — who noticed “several substantial issues with data and calculations.” For instance, before the experiment even started, the two groups had very different weights: The control group averaged 96.5 kg, and the test group 91 kg. According to the letter, that difference is striking: Continue reading Food article pulled when authors can’t serve up data

St. Jude investigation finds faked data in brain tumor paper

S00396060An investigation at St. Jude Children’s Hospital into “irregularities” in a figure featured in a neuroblastoma paper has concluded that the image was fabricated. The paper, published in Surgery in 2012, was retracted on Friday.

Here’s the full retraction notice for “Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition:”

Continue reading St. Jude investigation finds faked data in brain tumor paper

Heart researcher who faked patient data gets third retraction

Screen Shot 2015-11-06 at 6.38.09 PMA heart researcher has notched her third retraction, a small 2006 trial in Annals of Internal Medicine which seemed to show that a blood pressure drug could help people with artery disease walk further with less pain.

Earlier this year, Anna Ahimastos, formerly a researcher at Baker IDI Heart and Diabetes Institute in Melbourne, lost a larger clinical trial in JAMA and a subanalysis in Circulation Research after it was discovered she’d fabricated patient records. As principle investigator Bronwyn Kingwell told us in September:

Specifically, records were fabricated for trial participants that did not exist.

Now, following an investigation by the institute, her co-authors are proactively retracting papers, with more to come. The Annals of Internal Medicine paper, “Ramipril Markedly Improves Walking Ability in Patients With Peripheral Arterial Disease,” is being pulled due to an “inability to adequately validate primary data sources.” According to the note, Ahimastos “maintains the integrity of the data and validity of reported results:”

Continue reading Heart researcher who faked patient data gets third retraction

Study claiming dramatically higher rates of male military sexual trauma is retracted

psychological servicesA study that found a 15-fold increase in the rate of sexual trauma among men in the U.S. military — and sparked suggestions of “an epidemic of male-on-male sex crimes” in the military among conservative media outlets — has been retracted because of a flaw in the analysis.

The study, published just last week, appeared in Psychological Services, an American Psychological Association (APA) journal. In an announcement Sunday titled “American Psychological Association Retracts Article Positing Excessively High Rates of Sexual Trauma Among Military Men,” the APA said that “Scholars raised valid concerns regarding the design and statistical analysis which compromise the findings.” Here’s the text: Continue reading Study claiming dramatically higher rates of male military sexual trauma is retracted

Weekend reads: Elsevier mutiny; babies as co-authors; what to do after rejection

booksThis week’s Weekend Reads, which appears below, was preempted yesterday by the news that the Office of Research Integrity had issued a finding of misconduct in the long-running case of Anil Potti. The week also featured news about a child psychiatry trial halted for unexplained reasons, and saw the launch of our new weekly column at STAT, a new life sciences site from Boston Globe Media. Here’s what was happening elsewhere: Continue reading Weekend reads: Elsevier mutiny; babies as co-authors; what to do after rejection

It’s official: Anil Potti faked cancer research data, say Feds

potti
Anil Potti, via Duke

Following five years of scrutiny, more than ten retractions, multiple settled lawsuits, and medical board reprimands, we may finally have some resolution on the case of Anil Potti, the once-rising cancer research star who resigned from Duke in 2010.

While there have been numerous allegations of misconduct in Potti’s work, and strong comments to that effect by Potti’s former mentor, Joseph Nevins, there has been no official finding. Today, that changes. Potti “engaged in research misconduct,” the Office of Research Integrity (ORI) concludes in a report to be published in the Federal Register on Monday.

Potti — referred to as “respondent” in the report — included “false research data” in reports of research from six different NIH grants, according to the ORI: Continue reading It’s official: Anil Potti faked cancer research data, say Feds

Child psych studies halted for “unanticipated event,” sparking misconduct investigation

mpavuluri
Mani Pavuluri

We’ve just learned what sparked a University of Illinois at Chicago investigation that recently concluded a child psychiatrist had committed misconduct: An “unanticipated event during a study,” which halted three studies and resulted in a letter sent out to 350 research subjects.

Earlier this week, we reported that an investigation at the University of Illinois at Chicago found “a preponderance of evidence” that child psychiatrist Mani Pavuluri had committed misconduct. The university told the U.S. Department of Health and Human Services about the investigation in 2013. The findings of the investigation led the university to request the retractions of three papers, one of which has been pulled so far, for not properly disclosing how much medication children had received outside the study.

Today, we found out what prompted the university to launch that investigation, courtesy of a statement from a spokesperson: Continue reading Child psych studies halted for “unanticipated event,” sparking misconduct investigation

Authors withdraw two papers from JBC — and that’s all we know

44.cover

Two sets of authors have withdrawn their papers from the Journal of Biological Chemistry. We’re telling you about the both together because, true to JBC form, there’s not too much to say.

The retraction notices for both papers — about the molecular underpinnings of cardiac fibroblasts and melanoma cells — are identical:

Continue reading Authors withdraw two papers from JBC — and that’s all we know

Author’s coordination of peer review flags 13 math papers

home_cover (3)Thirteen papers in Mathematics and Mechanics of Solids now have an expression of concern, after it came to light that an author on most of the papers coordinated the peer-review process.

David Y. Gao, a well-known and prolific mathematician at the Federation University Australia, is the author of 11 of the papers, and also the guest editor of the special issue in which they were set to appear. The papers were published online earlier this year.

A spokesperson for SAGE, which publishes the journal, confirmed that the publisher decided to re-review the papers after learning about Gao’s role in the peer-review process:

Continue reading Author’s coordination of peer review flags 13 math papers