Category: clinical study retractions

PLOS ONE retracts breast cancer genetics paper after claim of misappropriated data

plosonePLOS ONE has retracted a 2012 article by a group of breast cancer researchers after another scientist — a leading U.S. oncologist — objected that the data came from his lab.

The paper, “GREB1 Functions as a Growth Promoter and Is Modulated by IL6/STAT3 in Breast Cancer,” came from a team composed of researchers at the Morehouse School of Medicine, Xavier University of Louisiana and the University of Miami School of Medicine. It purported to find that: Continue reading PLOS ONE retracts breast cancer genetics paper after claim of misappropriated data

Misconduct prompts retraction of prostatectomy paper

jsrcoverA group of urologists in China has lost their 2012 paper in the Journal of Surgical Research because one of the authors was evidently rather naughty.

The article, “Is the impact of the extent of lymphadenectomy in radical prostatectomy related to the disease risk? A single center prospective study,” purported to show that: Continue reading Misconduct prompts retraction of prostatectomy paper

CrossFit to be tied: Fitness company sues journal to retract “sloppy and scientifically unreliable work”

Lawsuits are usually dry and boring, so it’s always fun to read one with a little life.

Here’s one of those: CrossFit, the fitness program famous for its brief, strenuous exercises and passionate devotees, is suing the National Strength and Conditioning Association (NCSA), which it considers its staid competitor for the nation’s sweat and cash.

According to CrossFit, the NSCA published a study with a “falsified rate of injury,” “in an effort to portray CrossFit as ‘dangerous’ and therefore a fitness program that should be avoided.”

No matter that the study, published in NSCA’s official research journal, the Journal of Strength and Conditioning Research, concluded overall that CrossFit is a useful form of exercise. The suit says that the authors fudged a few statistics about participants’ injuries. Here’s the relevant section from the paper, titled “Crossfit-based high-intensity power training improves maximal aerobic fitness and body composition:”

Continue reading CrossFit to be tied: Fitness company sues journal to retract “sloppy and scientifically unreliable work”

If only more retractions could be like this: Authors of cardiac stem cell paper show the way

Researchers at Qingdao University have fully retracted a paper originally published in Molecular Medicine Reports with a clear, detailed outline of what went wrong and how they discovered the error.

Here’s the notice for “Generation of induced pluripotent stem cells using skin fibroblasts from patients with myocardial infarction under feeder-free conditions:”

Continue reading If only more retractions could be like this: Authors of cardiac stem cell paper show the way

Mystery box sinks immunology paper

Screen Shot 2014-06-30 at 12.30.32 PMBiochemical Journal has pulled a 2006 paper for an undisclosed “background subtraction box” in an image – which, if you take a not-particularly-close look at the figure to the right, means somebody added a black rectangle over the control lane.

Here’s the notice: for “Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4a transcriptional activity”: Continue reading Mystery box sinks immunology paper

Rapid mood swing: PNAS issues Expression of Concern for controversial Facebook study

pnas 1113The Proceedings of the National Academy of Sciences (PNAS) is subjecting a much-criticized study involving Facebook that it published just two weeks ago to an Expression of Concern.

From the abstract of the original study: Continue reading Rapid mood swing: PNAS issues Expression of Concern for controversial Facebook study

Author squabble sinks cardiology papers

Two papers on “novel techniques” have been retracted with what is unfortunately a very non-novel technique: an odd notice and silence when we asked for comment.

Here’s the explanation for retraction of “A novel approach to treat residual peridevice leakage after left-atrial appendage closure,” by Wunderlich N, Wilson N, and Sievert H: Continue reading Author squabble sinks cardiology papers

Bad spreadsheet merge kills depression paper, quick fix resurrects it

The authors of a paper showing a link between immune response and depression requested a retraction after they realized they’d merged two spreadsheets with mismatching ID codes.

Here’s the notice for “Lower CSF interleukin-6 predicts future depression in a population-based sample of older women followed for 17 years,” retracted in February 2014:

Continue reading Bad spreadsheet merge kills depression paper, quick fix resurrects it

Wayward “contractor” prompts expression of concern for PLoS ONE paper on cancer cells

logoThe editors of PLoS ONE have issued an Expression of Concern (which seems likely to become a retraction) for a 2014 paper by a group of researchers in China who claim to have been led astray by a contractor hired to “edit the language” of the report.

The article, “Arsenic Sulfide Promotes Apoptosis in Retinoid Acid Resistant Human Acute Promyelocytic Leukemic NB4-R1 Cells through Downregulation of SET Protein,” came from a group in the Department of Hematology at the First Affiliated Hospital at Xi’an Jiaotong University, and was led by Yuwang Tian, a pathologist at the General Hospital of Beijing Military Area of PLA.

Or at least that’s what the manuscript eventually said. According to the expression of concern, however, that’s not what it said initially: Continue reading Wayward “contractor” prompts expression of concern for PLoS ONE paper on cancer cells

Alleged Medicare cheat loses paper for data mix-up

A Boston doctor indicted on charges of Medicare fraud in 2007 has had a paper relating to the case retracted this month.

Abdul Razzaque Ahmed was considered something of a miracle worker by his patients, treating two rare and disfiguring skin conditions called pemphigoid and pemphigus vulgaris. He used more powerful medicines than the typical course of treatment, including a drug normally used to treat cancer.

The initial indictment stated that Ahmed mixed blood samples to falsely show a “dual diagnosis” of both diseases, and prove to Medicare that they required the more rigorous (and expensive) treatment. It also alleged that he profited massively from the government pay-outs. He was convicted of obstruction in 2007; the other charges were dropped when he agreed to forfeit assets worth $2.9 million.

Now, a 2001 paper by Ahmed, which claimed fifteen patients had a dual diagnosis, has been retracted because the samples were all mixed. Here is the retraction notice from Clinical Immunology: Continue reading Alleged Medicare cheat loses paper for data mix-up