by subject – Page 44 – Retraction Watch

“I sincerely apologise:” UK cancer researcher calls for retraction of his work years after it’s flagged on PubPeer

A cancer researcher in England says he will be retracting a 2011 paper after acknowledging “unacceptable” manipulation of some of the figures in the article.

Richard Hill, of the University of Portsmouth, this week agreed to retract the article, “DNA-PKcs binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death,” which appeared in the journal Oncotarget.

The paper, which Hill wrote while he was at Dalhousie University in Halifax, Nova Scotia, had drawn scrutiny on PubPeer four years ago, with one poster noting “many indications of blot image manipulation” in the figures. Additional comments appeared earlier this month.

In a comment on PubPeer posted this week, Hill wrote:

Hepatitis expert up to five retractions and one expression of concern denies reusing images

A microbiology journal has issued an expression of concern over image reuse in a 2010 paper whose senior author has already racked up five retractions for duplicating figures.

The article, “Activation of transcription factor Nrf2 by hepatitis C virus induces the cell-survival pathway,” appeared in the Journal of General Virology, a publication of the Microbiology Society. The last author of the paper is Gulam Waris, an expert in viral hepatitis who is on the faculty of the Rosalind Franklin University of Medicine and Science in North Chicago. The paper has been cited 75 times, according to Clarivate Analytics’ Web of Science.

By our count, Waris — whose work has made several appearances in PubPeer — has lost at least five papers to retraction for image duplication and questionable data.

Paper used to support ban on Caster Semenya competing earns massive correction

The authors of a controversial paper on what constitutes “normal” hormone levels in men and women — and, by implication, “male” and “female” athletes — are set to issue a massive correction of the work, Retraction Watch has learned. But an outside, albeit not disinterested, researcher who prompted the correction says the correction itself is amiss.

The article, “Large divergence in testosterone concentrations between men and women: frame of reference for elite athletes in sex-specific competition in sports, a narrative review,” appeared earlier this year in Clinical Endocrinology, a Wiley title. The authors of the meta-analysis, led by Richard Clark, of the US Anti‐Doping Agency, argued that testosterone levels between the sexes do not overlap in the absence of chromosomal or genetic anomalies that blur the distinction between male and female.

That finding was cited recently by an architect of the International Association of Athletics Federations’ decision to bar the South African trackstar, Caster Semenya, and other “hyperandrogenic” women (Semenya’s hormonal status has not been made public) whose hormonal constitution is arguably more male than female.

Meta-meta-analysis meets with retraction for group that had faked peer review elsewhere

Researchers in China have lost a 2015 meta-analysis on pancreatic cancer, one of several retractions for members of the group stemming from a variety of abuses including bogus authorship and fake peer review.

The meta-analysis, “Correlation between serum levels of high mobility group box-1 protein and pancreatitis: a meta-analysis,” appeared in BioMed Research International, a Hindawi journal. The authors are affiliated with China Medical University in Shenyang and Shanghai Jiao Tong University.

Here’s the notice:

Journal expresses a great deal of concern over deceased author’s work

A gastroenterology journal has issued an extensive expression of concern about a 2013 paper by Yoshihiro Sato, a Japanese endocrinologist who has posthumously been climbing the Retraction Watch leaderboard. (He’s now ranked number three, ahead of Diederik Stapel.)

To call the statement an “expression of concern” is like calling Charles M. Schulz a talented cartoonist, or Escoffier a pretty good cook. Indeed, the journal expresses so much concern, about, well, so much, that we’re not sure what in the paper would be left unscathed.

Sato, formerly of Hirosaki University, currently has 77 retractions for a range of misconduct-related issues including likely data fabrication and duplication.

Cock and bull story leads to retraction of bovine herpesvirus paper

The ancients had a thing for hybrids (think animals, not cars): half goat-half humans, horses with human torsos, winged horses and lions, you get the picture. But a chicken-cow mix wasn’t on that list … until now.

A group of researchers in Brazil has lost a paper in a veterinary journal for trying to reuse data from a poultry study in their paper on herpesvirus infections in cattle.

The article, “Bovine Herpesvirus 5 promotes mitochondrial dysfunction in cultured bovine monocyte-derived macrophages and not affect virus replication,” appeared in February in the journal Veterinary Microbiology.

According to the retraction notice:

Cancer specialists in Mexico earn third retraction following questions about their data

Cases of cancers seen at the Instituto Mexicano del Seguro Social, according to researcher Agustin Avilés

A group of cancer researchers in Mexico has lost their third paper over concerns about the integrity of their data.

Neither the new retraction, in the journal Hematology, nor the previous two, cite misconduct as the reason for the removals. However, the statements do refer to lack of reliability of results, “ambiguities and inconsistencies” in the findings and other serious issues.

The first author on each paper is Agustin Avilés, whom the Hematology article listed as being with the National Medical Center in Mexico City.

According to the retraction notice:

Chemistry researcher who studies oil wells is up to seven retractions

A chemistry researcher in India is up to seven retractions and one correction for problematic images and other issues.

The researcher, Mahendra Yadav, was the first author on an article titled “Corrosion inhibition of tubing steel during acidization of oil and gas wells,” which appeared in 2013 in the Journal of Petroleum Engineering (JPE). Yadav, who also has a correction for similar concerns, and who has a fairly extensive entry in PubPeer, is listed as being affiliated with the Department of Applied Chemistry at the Indian School of Mines, in Dhanbad.

According to the notice:

Stanford calling for retractions of work by deceased star cancer researcher

The Journal of Clinical Investigation has retracted two papers from the lab of one of Stanford University’s most prominent cancer researchers over concerns about the integrity of the data.

The articles, published in 2012 and 2014, described work on ways of priming the immune system to enhance the activity of drugs to fight cancer.

The first author on the two articles was Holbrook “Brook” Kohrt, a superstar young faculty member who died in 2016 of complications of hemophilia. Kohrt was the subject of this 2013 profile in the New York Times, which also wrote an obituary of him.

Catholic medical journal pulls paper on conversion therapy over statistical problems

The journal for a religious medical group is retracting a paper that supported the discredited practice of conversion therapy for homosexuals over concerns about the statistical analyses — or lack thereof — in the research.

The paper, “Effects of therapy on religious men who have unwanted same-sex attraction,” was published last year in The Linacre Quarterly, the official journal of the Catholic Medical Association. (According to its website: “LQR explores issues at the interface of medicine and religion, focusing on bioethics and also exploring medical topics which have an ethical dimension.)

So, what were those effects? Pretty darn good, according to the article. Per the abstract:

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