Category: clinical study retractions

Authors retract green coffee bean diet paper touted by Dr. Oz

green coffee beanTwo authors of a 2012 paper sponsored by a company that made grand claims about green coffee bean extract’s abilities to help people lose weight have retracted it. The study was cited by The Dr. Oz Show, and last month it cost the company a $3.5 million settlement with the Feds.

Here’s the notice for “Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects,” a paper originally published in Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy: Continue reading Authors retract green coffee bean diet paper touted by Dr. Oz

Journal expresses concerns over “possible data irregularities” in paper from Army medical center docs

JAADThe Journal of the American Academy of Dermatology has issued an expression of concern about a 2012 article reporting the experience of military burn unit treating a rare ailment called toxic epidermal necrolysis.

According to the notice, which is behind a paywall (for shame!), the paper appears to have overstated the number of cases the hospital itself has treated of the life-threatening condition: Continue reading Journal expresses concerns over “possible data irregularities” in paper from Army medical center docs

Authors retract HER-2 endometrial cancer paper for 2x publication

OGSFile this one under strange excuses.

A cancer paper was retracted on September 17 for a double publication. According to the notice in which the authors admit to duplicating the “opening to the readers,” which we assume is the introduction, there was no need to cite the article “because it had not yet been printed at that time.”

Here’s the notice for “The effect of HER-2 polymorphism according to age on the risk and pathologic feature of endometrial cancer”: Continue reading Authors retract HER-2 endometrial cancer paper for 2x publication

Asthma study yanked for serious ethical violations

springerplusA paper in SpringerPlus on treating asthma with antioxidants was retracted on September 25 for something of a trifecta of ethical problems.

The retraction notice indicates that the patients never consented, there was no ethical review, and the university supposedly overseeing the study had no knowledge of it:

Continue reading Asthma study yanked for serious ethical violations

Cell line switch sinks PLoS ONE cancer paper

plosWe’ve written before about how common cell line mix ups are in cancer research; according to a 2012 Wall Street Journal article (paywalled), between a fifth and a third of cancer cell lines tested by suspicious researchers turned out to be misidentified.

Obviously, mistakenly studying the wrong kind of cancer is a waste of precious resources, both time and money. And it’s clear the problem hasn’t gone away. PLoS ONE just retracted a cancer paper originally published in December 2012 for studying two cell lines that had been contaminated by other cell types.

Here’s the notice for “Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma”:
Continue reading Cell line switch sinks PLoS ONE cancer paper

Yet another study of widely touted cancer “cure” retracted

cancer immunology immunotherapyA third study of GcMAF, a protein being used to treat a variety of conditions from AIDS to autism to cancer, all without the blessing of health agencies, has been retracted.

Here’s the notice in Cancer Immunology, Immunotherapy for “Immunotherapy of metastatic colorectal cancer with vitamin D-binding protein-derived macrophage-activating factor, GcMAF:” Continue reading Yet another study of widely touted cancer “cure” retracted

Journal makes it official, retracting controversial autism-vaccine paper

translational neurodegenerationA little more than a month after removing a highly criticized article that claimed the measles-mumps-rubella (MMR) vaccine increased the risk of autism in African American boys, Translational Neurodegeneration has officially retracted the paper.

Here’s the notice, dated yesterday: Continue reading Journal makes it official, retracting controversial autism-vaccine paper

Critics of Poldermans’ work baffled by NEJM stance on DECREASE papers

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Don Poldermans

A pair of researchers who have been calling for the retraction of two papers by cardiology researcher Don Poldermans say the New England Journal of Medicine is  “not justified” “disappointing” in its refusal to pull the articles.

A little background: Poldermans resigned from Erasmus University in 2011 after having been accused of misconduct. Last week, we reported that the European Heart Journal had issued an expression of concern for a 2001 article on which he was first author.

The New England Journal of Medicine added editor’s notes to two of Poldermans’ articles. But as Larry Husten at Forbes reports, the journal has no intention of retracting the papers: Continue reading Critics of Poldermans’ work baffled by NEJM stance on DECREASE papers

Publisher issues statement of concern about HIV denial paper, launches investigation

frontiers phThe publisher Frontiers has issued a Statement of Concern about a paper denying that HIV causes AIDS, and has launched an investigation into how the paper was published in the first place.

The paper, “Questioning the HIV-AIDS hypothesis: 30 years of dissent,” is written by Patricia Goodson of Texas A&M University and was published on September 23 in Frontiers in Public Health. As Tara Smith, who blogged about the paper yesterday, notes: Continue reading Publisher issues statement of concern about HIV denial paper, launches investigation

Notice fails to get to the heart of cardiology retraction

cmjThis one is a little odd.

A cardiology paper from China has been retracted because “permission to report these discussions was not sought nor obtained,” though it’s unclear what “the discussions” refers to. The person to whom the discussions are attributed to in the retraction, Ji Bingyang, is not an author on the paper, and none of his papers are cited in the retracted article.

Here’s the notice in the Chinese Medical Journal for “A novel rat model of cardiopulmonary bypass for deep hypothermic circulatory arrest without blood priming”:
Continue reading Notice fails to get to the heart of cardiology retraction