Category: clinical study retractions

Nature Cell Biology insulin paper retracted over antibody problems

nature cell biologyA Nature Cell Biology article on insulin regulation has been retracted after scientists noted that the antibodies used in their research were not as specific as they had previously believed.

The notice is clear on the problems with the science, which together “call into question the main conclusions of the paper.” Three of the paper’s five authors were employed at Novartis at the time of publication.

Here’s the notice for “Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion”: Continue reading Nature Cell Biology insulin paper retracted over antibody problems

Paper recommending calorie limits on Happy Meals retracted

Image via Stefan

A paper estimating the effects of limiting fast food meals with toys to under 550 calories has been retracted after concerns arose regarding the scientists’ use of an outdated model for estimating weight changes in kids.

The paper estimated that kids who eat fast food twice a week would avoid gaining two pounds a year if calorie limits are imposed on meals with toys. However, everyone we spoke to, and the notice, indicated that their estimate was inaccurate.

Here’s the notice for “Modeling Potential Effects of Reduced Calories in Kids’ Meals with Toy Giveaways”:

Continue reading Paper recommending calorie limits on Happy Meals retracted

Mix-and-match text topples microbiome paper

iemA group of gastroenterology researchers in Italy has lost their 2010 paper in Internal and Emergency Medicine, the journal of the Italian Society of Internal Medicine, for plagiarizing and duplicate publication.

The article, “Gut microbiota and related diseases: clinical features,” was published as a supplement by a team from the University of Bologna. Its conclusions: Continue reading Mix-and-match text topples microbiome paper

Shingles-stroke connection paper earns expression of concern for “errors in data presentation”

neurologyThe journal Neurology has issued an expression of concern for a paper linking shingles and stroke, which got press attention when it was published.

The journal’s note refers to “errors of data presentation,” which author Judith Breuer more narrowly defined as mistakes during transcription of a table. It’s unclear whether the results themselves – that herpes zoster, the virus that causes shingles, is a risk factor for stroke and other vascular problems – are being called into question.

Here’s the expression of concern for “Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK”: Continue reading Shingles-stroke connection paper earns expression of concern for “errors in data presentation”

ORI sanctions former University of Chicago and UCSF scientists for faking findings

H. Rosie Xing
H. Rosie Xing

The stories behind several recent inscrutable retraction notices became a bit more clear today when the Office of Research Integrity (ORI) issued findings in cases involving former researchers at the University of Chicago and the University of California, San Francisco.

The ORI found that H. Rosie Xing, a former assistant professor at the University of Chicago, Continue reading ORI sanctions former University of Chicago and UCSF scientists for faking findings

Dentistry student loses travel grant for duplicating his own work

iadrThe International Association for Dental Research has retracted a student travel award after discovering that the recipient had previously published the work he used to secure the grant, including in an abstract he presented at the same conference last year.

The self-plagiarism was uncovered by an anonymous group of students at the Hong Kong University dentistry school, where the student is a PhD student. The unnamed students sent both the IADR and HKU faculty members a color-coded chart showing identical phrases between the 2014 abstract, a 2013 paper published in the Journal of Periodontal Research called “Human umbilical vein endothelial cells synergize osteo/odontogenic differentiation of periodontal ligament stem cells in 3D cell sheets,” and another abstract the authors presented at the 2013 IADR conference.

The paper and both abstracts were written by P.K.C.P. Panduwawala, who lost the travel grant, along with HKU’s former dean of dentistry L.P. Samaranayake; HKU’s associate dean for research L.J. Jin; and C.F. Zhang, part of HKU’s tissue engineering group.

The IADR’s page now lists the winners with a note at the bottom: Continue reading Dentistry student loses travel grant for duplicating his own work

JCI lymphoma paper retracted after authors can’t find underlying data to explain duplicated bands

Screen Shot 2014-11-25 at 5.12.55 PMA paper in the Journal of Clinical Investigation has been retracted for manipulated images, including duplicated bands in a Western blot.

Take a look at figure one to the right and see if you can spot all the doubles.

Click here for a more zoomable image.

Here’s the notice: Continue reading JCI lymphoma paper retracted after authors can’t find underlying data to explain duplicated bands

COPD paper in JCI retracted following PubPeer critiques

jciA 2011 paper in the Journal of Clinical Investigation whose PubPeer entry we highlighted in September has been retracted.

Here’s the notice for “Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients,” a 2011 paper by researchers at Johns Hopkins and Imperial College: Continue reading COPD paper in JCI retracted following PubPeer critiques

Psych paper falls afoul of journal’s plagiarism policy (hint: don’t plagiarize)

jcpharmacopharmThe Journal of Clinical Psychopharmacology has retracted a 2011 paper on depersonalization disorder by a pair of authors in Azerbaijan who got a bit too familiar with their source material without proper attribution. And the journal has offered its readers a handy — if depressingly obvious — admonition about publication ethics.

The article, “Lamotrigine in the immediate treatment of outpatients with depersonalization disorder without psychiatric comorbidity. Randomized, double-blind, placebo-controlled study,” by researchers at the Central Mental Clinic for Outpatients of Baku City, purported to find that: Continue reading Psych paper falls afoul of journal’s plagiarism policy (hint: don’t plagiarize)

PubPeer strikes again: Leukemia paper retracted for image duplications

bbaIn July, a PubPeer commenter called out a paper in Biochimica et Biophysica Acta for image duplication; by September, the paper was retracted for the exact reason detailed in the anonymous comment.

Here’s the notice for “Effect of ST3GAL 4 and FUT 7 on sialyl Lewis X synthesis and multidrug resistance in human acute myeloid leukemia,” a paper initially published in June: Continue reading PubPeer strikes again: Leukemia paper retracted for image duplications