Category: clinical study retractions

Neuroanatomy paper riddled with errors pulled by authors

Journal-of-NeurosurgeryAuthors have retracted a paper from the Journal of Neurosurgery that contained many errors, including mislabeled figures, anatomical errors, and mismatched citations. They said that the paper’s preparation was rushed and not all authors had a chance to verify that it was accurate.

Two of the authors of the paper had previously contacted the journal to request the paper be withdrawn. Jo Ann Eliason, communications manager for the Journal of Neurosurgery, said that the withdrawal request came too late, since the paper had already been published online: Continue reading Neuroanatomy paper riddled with errors pulled by authors

Eight retractions for fake reviews lead journal to suspend author nominations

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An investigation has uncovered fake reviews on 21 papers submitted to the Journal of the Renin-Angiotensin Aldosterone System.

After taking a second look at accepted papers with an author-nominated reviewer, the journal discovered that the listed reviewers on the 21 papers, though real people, had never submitted a report.

Eight of the papers have been retracted by JRAAS. The rest had not yet been published, and have now been rejected, explains a commentary by the journal editors. The journal has also stopped allowing authors to nominate reviewers.

The retraction note — the same on all eight papers — explains how the authors “seriously compromised” the review process:

Continue reading Eight retractions for fake reviews lead journal to suspend author nominations

Oh no he didn’t! Misattributed Aristotle work leads to correction in highly cited cancer paper

jcoJohn Shannon may be a mere undergrad at Hillsdale College in Michigan, but he knows enough about history to be surprised that Aristotle had written an entire book about economics that Shannon had never heard of.

That curiosity led to the discovery that a highly cited paper about pricing in cancer drugs was missing a reference to a rather relevant source about a treatise by the Greek philosopher, prompting the Journal of Clinical Oncology to correct the paper. But to Shannon, a missing reference is not the only problem with the paper.

As he notes in an essay in Public Discourse, Shannon’s interest was piqued when he noticed this passage in a 2013 paper in the Journal of Clinical Oncology on the fair price — “just price,” or Justum Pretium — of cancer drugs: Continue reading Oh no he didn’t! Misattributed Aristotle work leads to correction in highly cited cancer paper

Authors retract antioxidant paper after more work reverses their conclusion

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The authors of a paper about the benefits of an antioxidant found in blueberries known as pterostilbene have retracted it after their subsequent research suggested the antioxidant might actually be harmful.

The paper presented evidence that the antioxidant might help rats after heart attack, in part by inhibiting cell death (apoptosis). But according to the retraction note, more work

found that pterostilbene might induce apoptosis in the heart and can be harmful, and we are now focusing on the phenomenon.

The rest of the retraction note for “Pterostilbene attenuates inflammation in rat heart subjected to ischemia-reperfusion: role of TLR4/NF-κB signaling pathway,” published in the International Journal of Clinical and Experimental Medicine, suggests that the authors would consider republishing their findings if they became more confident in the data:

Continue reading Authors retract antioxidant paper after more work reverses their conclusion

Science flags immune-boosting paper under investigation

F1.mediumScience magazine has issued an expression of concern for a paper on the discovery of a new immune-boosting protein. The paper’s findings, which received some press coverage when they came out last spring, are now under investigation by Imperial College London.

The expression of concern follows a correction noting a Western blot mix-up. Science Editor in Chief Marcia McNutt told us last month that the mistake resulted from “carelessness” on the part of the authors. But now, an investigation at Imperial College London — where Philip Ashton-Rickardt led the research — is formally looking into the findings.

That investigation is ongoing, according to the expression of concern (signed by McNutt):

Continue reading Science flags immune-boosting paper under investigation

Authors retract meningitis paper over permission — but data are in a public database

plos1A study characterizing subtypes of the bacteria that cause bacterial meningitis is being retracted after the authors didn’t have permission to publish the data, even though the data itself remain available in a public database.

The paper, in PLOS ONE, relied on a laboratory collection of patient samples. In October, the authors retracted it because they “did not have permission” from the laboratory “to publish the data in their current form.” The data — anonymized — are now available at PubMLST.

Here’s the retraction notice, published on October 16: Continue reading Authors retract meningitis paper over permission — but data are in a public database

Breakfast study mischaracterized funding by cereal group

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PLOS ONE has quickly corrected an October analysis of what children in Malaysia eat for breakfast, after the study neglected to note it benefited from mistakenly noted an unrestricted research grant from cereal companies supported author salaries. The grant supported the salaries of research assistants, according to the correction note.

Per the authors’ request, the journal has noted that the study received financial support from Nestlé R&D Center in Singapore and Cereal Partners Worldwide, a collaboration between General Mills Inc. and Nestlé S.A., with the goal of selling cereal outside the US and Canada. These funders provided “salaries for research assistants” for the MyBreakfast study, on which the analysis is based, according to the note.

The paper includes authors affiliated with Nestlé and Cereal Partners Worldwide, as well as a detailed “Competing interests” section, which outlines the relationships with these companies.

The correction note explains the information that should have appeared in the funding section of the article:

Continue reading Breakfast study mischaracterized funding by cereal group

“Compromised” peer review hits three papers from Nature Publishing Group

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Nature Publishing Group is retracting three papers today, after an investigation found evidence the peer-review process had been compromised.

The publisher issued a statement saying they had notified corresponding authors and institutions associated with the three papers, which were all published last year in the journals Cancer Gene Therapy and Spinal Cord. 

Here’s the note that’s going on each of the papers, (they’re the same, except for the publication date):

Continue reading “Compromised” peer review hits three papers from Nature Publishing Group

Fifth retraction for Wayne State researcher who fudged figures

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Teresita L. Briones

Another retraction has appeared for Teresita Briones, who used to study neuroscience at Wayne State University — the final of five papers flagged by the Office of Research Integrity for containing falsified data.

According to the ORI notice published in May, Briones “intentionally, knowingly, and recklessly engaged in research misconduct by falsifying and/or fabricating data.” This latest paper to be retracted, which looks at the role of specific receptor in chronic inflammation of nervous tissue in rats, has two figures that “were duplicated, reused and falsely relabelled, and claimed to represent different experiments,” according to the retraction note.

The retraction note for “Chronic neuroinflammation and cognitive impairment following transient global cerebral ischemia: role of fractalkine/CX3CR1 signaling,” published in the Journal of Neuroinflammation, specifies the problematic figures:

Continue reading Fifth retraction for Wayne State researcher who fudged figures

“The peer review process was compromised”: Inflammation drug paper pulled

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A paper that screened for antibodies that target TNFα, a major source of inflammation, has been retraction after an investigation revealed the peer-review process may have been compromised.

We’ve seen the peer review process “compromised” in a handful of ways — from a mathematician who oversaw the process on several of his own papers, to some 250 papers subject to outright fake peer review. The note for this paper, published in Amino Acids, doesn’t go into details, so we can only wonder what happened in this particular case.

Here’s the note for “Structure‑based development and optimization of therapy antibody drugs against TNFα:”

Continue reading “The peer review process was compromised”: Inflammation drug paper pulled