Category: clinical study retractions

Paper on GI cancers linked to AIDS pulled for errors that upped tumor incidence

gastroGastroenterology has retracted a 2012 article on GI cancers associated with AIDS after the authors, from the National Cancer Institute, acknowledged that a “programming” error led them to overestimate the incidence of the tumors.

The paper, “Increased Risk of Stomach and Esophageal Malignancies in People With AIDS,” received a significant amount of attention when it first appeared, including a press release from the American Gastroenterological Association and several news articles. Here are its primary findings, according to the abstract:  Continue reading Paper on GI cancers linked to AIDS pulled for errors that upped tumor incidence

Seven papers flagged earlier for fake reviews now retracted by Elsevier

elsevierElsevier has now retracted the seven papers it flagged in October as being affected by fake peer reviews.

If you’re not keeping track, we are: We have logged a total of about 300 retractions for fake peer review, in which some aspect of the peer-review process becomes compromised — for instance, in the case of the newly retracted papers, authors appear to have created fake email accounts in order to pose as reviewers and give the green light to their own papers.

The same retraction note applies to five of the recently retracted papers:

Continue reading Seven papers flagged earlier for fake reviews now retracted by Elsevier

Scientists call for retraction of “seriously misleading” paper with asbestos industry ties

EBPHEleven scientists are asking a journal to consider retracting an asbestos paper with industry ties for including “seriously misleading information,” “several wrong statements,” and thrice citing a journal that doesn’t appear to exist.

Editors of the journal, Epidemiology Biostatistics and Public Health, however, say they will not retract the article, based on the advice of two external reviewers.

An earlier correction for the paper,  “Further Studies of Bolivian Crocidolite – Part IV: Fibre Width, Fibre Drift and their relation to Mesothelioma Induction: Preliminary Findings,” cited previously undisclosed competing interests for four of the paper’s five authors.

Earlier this year, scientists criticized “gross mistakes” in another paper from three of the same authors: Edward Ilgren, Yumi Kamiya, and John Hoskins. EBPH subsequently issued two corrections but did not retract that paper. Read our full coverage here. Continue reading Scientists call for retraction of “seriously misleading” paper with asbestos industry ties

Poll: Should co-authors of a scientific paper be allowed to change their minds?

lancetSince we reported Friday that multiple authors had asked to remove their names from a high-profile 2011 Lancet paper about a risky transplant surgery, a few readers have wondered: Should this be allowed?

To recap: The same day the journal announced it was tagging the controversial paper with an expression of concern, it issued a new erratum about the paper, removing three author names (one had already asked to be removed earlier). The highly cited paper has been under scrutiny ever since the last author, Paolo Macchiarini, has been facing allegations of misconduct, which most recently led to Macchiarini’s dismissal from the Karolinska Institutet. (Here’s our timeline of events to keep you abreast.)

It’s not surprising that a few of Macchiarini’s co-authors would want to distance themselves from this ever-expanding scandal, but should authors who originally signed onto a paper be able to change their minds? Let us know in our poll, below. Continue reading Poll: Should co-authors of a scientific paper be allowed to change their minds?

Five more notices for Duke pulmonary pair brings retraction tally into double digits

Two retractions and three corrections have appeared for a group of Duke researchers that already have 10+ retractions under their belts.

The reasoning behind them echoes that which we’ve seen before in notices for Michael Foster and Erin Potts-Kant: Following an inquiry from the university, the journals were informed that some of the data or results weren’t reliable, and not all of the experiments could be repeated.

A colleague aware of the case said that researchers are still working to repeat experiments from papers by Potts-Kant and Foster. It is not known how many more papers might be corrected or retracted. Duke University is fully supporting the validation of these experiments, the source told us.

Foster has retired from Duke, a spokesperson for the university confirmed. Continue reading Five more notices for Duke pulmonary pair brings retraction tally into double digits

Lancet issues expression of concern for 2011 Macchiarini paper

Paolo Macchiarini
Paolo Macchiarini

The Lancet has tagged an expression of concern onto a seminal 2011 paper by Paolo Macchiarini, the Italian surgeon whose work and conduct outside the operating room has earned months of  heavy criticism that recently culminated in his dismissal from the Karolinska Institutet.

“Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study,” which described the first case of a transplant using an artificial trachea seeded with the patient’s own stem cells, now bears an expression of concern from The Lancet editors, citing ongoing investigations. The journal has also removed three more authors from the paper, upon their request.

The expression of concern essentially presents the timeline of the controversy that led the journal to make this move:

Continue reading Lancet issues expression of concern for 2011 Macchiarini paper

Poop paper flushed due to possible sample contamination

cover (3)The authors of a paper on a new probiotic strain of bacteria found in pig feces have retracted it from Animal Science Journal after discovering some of the bacteria might have been contaminated.

Readers likely know by now how easy it is for this to happen, as we frequently report on retractions due to similar reasons. Like other instances of mistaken cell identity, the authors of this 2013 paper realized the mistake following further tests of the bacteria used in the experiment.

The retraction for “Isolation, characterization, and effect of administration in vivo, a novel probiotic strain from pig feces”

Continue reading Poop paper flushed due to possible sample contamination

What if we tried to replicate papers before they’re published?

Martin Schweinsberg
Martin Schweinsberg
Eric Uhlmann
Eric Uhlmann

We all know replicability is a problem – consistently, many papers in various fields fail to replicate when put to the test. But instead of testing findings after they’ve gone through the rigorous and laborious process of publication, why not verify them beforehand, so that only replicable findings make their way into the literature? That is the principle behind a recent initiative called The Pipeline Project (covered in The Atlantic today), in which 25 labs checked 10 unpublished studies from the lab of one researcher in social psychology. We spoke with that researcher, Eric Uhlmann (also last author on the paper), and first author Martin Schweinsberg, both based at INSEAD.

Retraction Watch: What made you decide to embark upon this project? Continue reading What if we tried to replicate papers before they’re published?

Upon request, NEJM added note to help Texas distance itself from Planned Parenthood article

Screen Shot 2016-03-30 at 1.41.39 PM

The New England Journal of Medicine added a disclaimer to a recent article about the effects of funding cuts to Planned Parenthood, after a request from the Texas Health and Human Services Commission, saying it wanted to distance itself from the paper.

Since the paper was published in February, one author has stepped down from his position at HHSC after facing disciplinary action.

The article suggested that birth rates among a group of lower-income women increased after the state cut down on support for Planned Parenthood. It drew a significant amount of media attention — and concern from the HHSC, which asked the journal to add a disclaimer to the article soon after publication. The journal complied, but embargoed the announcement of the change until 5 p.m. eastern time today.

Here’s the disclaimer that NEJM added to the article:

Continue reading Upon request, NEJM added note to help Texas distance itself from Planned Parenthood article

Study on teens with scoliosis failed to seek ethics approval, erratum notes

Screen Shot 2016-03-07 at 3.29.57 PMAfter researchers failed to seek ethics approval for a study on teens with scoliosis, a journal has issued an erratum to the paper.

The journal is not retracting the paper outright, it says, because the study was non-invasive and likely would have received ethics approval.

During the study, teenagers with and without progressive scoliosis underwent a physical examination and participated in an interview along with a parent, with the goal of trying to uncover risk factors for the condition.

Here’s the full erratum from Scoliosis and Spinal Disorders for “Physical activities of Patients with adolescent idiopathic scoliosis (AIS): preliminary longitudinal case–control study historical evaluation of possible risk factors:”

Continue reading Study on teens with scoliosis failed to seek ethics approval, erratum notes