Category: basic life sciences retractions

Neuroscientist in Serbia set to notch 7th retraction amid investigation

Lidija Radenović

Amidst an ongoing investigation by the University of Belgrade in Serbia into allegations of duplication by neurobiologist Lidija Radenović, a journal is planning to retract another one of her papers.

Radenović has already racked up six retractions; Elinor Ben-Menachem, the chief editor of the journal, Acta Neurologica Scandinavica, confirmed her journal is planning to retract one paper co-authored by Radenović, but did not specify which one. After digging around on the journal’s website, we found only one paper co-authored by Radenović, which was a 2005 study about the molecular changes that follow stroke. 

Ben-Menachem, who is based the University of Gothenburg in Sweden, said the retraction note for the paper is “not ready” yet, and declined to comment on the case in more detail, including the reason for retraction. Continue reading Neuroscientist in Serbia set to notch 7th retraction amid investigation

Image splicing, duplications, inversions kill paper for well-known longevity researcher and alum of lab

Gizem Domnez
Gizem Donmez

A well-known scientist at the Massachusetts Institute of Technology who studies longevity has retracted a paper for “numerous examples of unindicated splicing of gel lanes,” as well as other problems.

This is Leonard Guarente‘s second retraction. He shares both with Gizem Donmez, an alum of his lab who now has three retractions. Donmez left her post as a Tufts professor in 2014.

Guarente told us in March — when we reported that he’d published a mega-correction on another paper — that he had planned to address issues with the paper, “SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones,” published in the The Journal of Neuroscience. Now, a retraction note has appeared “at the request of the authors.” It explains:

Continue reading Image splicing, duplications, inversions kill paper for well-known longevity researcher and alum of lab

Does this scientific image look familiar? It’s from a catalog

cover (4)There’s something strange about a 2008 paper on the role of nicotine receptors in promoting lung cancer: One of the western blot analyses looks like a version of an image from a commercial catalog.

A commenter on PubPeer pointed out the similarities between an image in “Role of α7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation,” which was published in Cell Proliferation, and one used to promote an enzyme sold by Cell Signaling Technology.

Unfortunately, if the images are indeed the same, we can’t tell for certain who copied from whom. But a representative of the company told us it generates its own images, and this one was likely created before the paper was published. The last author — for whom we’ve found three other retractions — denied that the paper copied the image.

Here’s the panel from the paper, which was published in 2008: Continue reading Does this scientific image look familiar? It’s from a catalog

Authors pull 14-year-old paper from PNAS over concerns of fabrication

13.coverAuthors have retracted a 2002 paper from PNAS because part of a figure “may have been fabricated,” and they no longer have the original data to prove otherwise.

The paper in question, “Deficient Smad7 expression: A putative molecular defect in scleroderma,” studied the signaling pathways that may underlie the autoimmune disease. It has been cited 198 times, according to Thomson Reuters Web of Science.

The authors, led by Pascal J Goldschmidt-Clermont, currently the Dean of the School of  Medicine at the University of Miami, have issued a retraction note, which appeared online yesterday: Continue reading Authors pull 14-year-old paper from PNAS over concerns of fabrication

Cancer researcher earns 9th retraction, for image duplication

Journal of Clinical InvestigationAlfredo Fusco, a researcher in Italy who has been under criminal investigation for scientific misconduct, has earned his ninth retraction.

Retraction number nine, by The Journal of Clinical Investigation, is for duplicating data from another publication — which has also faced questions on PubPeer about image manipulation, along with many other papers by Fusco.

The retraction note for “The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells” explains that the journal is pulling the paper even though the authors claim that they can reproduce the data:

Continue reading Cancer researcher earns 9th retraction, for image duplication

Poop paper flushed due to possible sample contamination

cover (3)The authors of a paper on a new probiotic strain of bacteria found in pig feces have retracted it from Animal Science Journal after discovering some of the bacteria might have been contaminated.

Readers likely know by now how easy it is for this to happen, as we frequently report on retractions due to similar reasons. Like other instances of mistaken cell identity, the authors of this 2013 paper realized the mistake following further tests of the bacteria used in the experiment.

The retraction for “Isolation, characterization, and effect of administration in vivo, a novel probiotic strain from pig feces”

Continue reading Poop paper flushed due to possible sample contamination

Neuroscientist pleads guilty in court to fraud, gets two-year suspended sentence

Bruce Murdoch
Bruce Murdoch

A Parkinson’s researcher pleaded guilty to fraud in court this morning in Brisbane, Australia, and received a two-year suspended sentence.

Court sentences for fraud are rare, to say the least. This one follows an investigation by Bruce Murdoch‘s former employer, the University of Queensland, into 92 papers — resulting in the retraction of three papers co-authored by Caroline Barwood, also facing fraud charges. The investigation was unable to find any evidence that published research cited in court had been ever carried out.

The Australian reported this morning that Murdoch:

Continue reading Neuroscientist pleads guilty in court to fraud, gets two-year suspended sentence

Mystery conflict between authors fells molecular bio paper

mirna-journal-coverA journal has pulled a paper about tools to knock out a key transcription factor because of a conflict between the authors.

The retracted article is “Generation of Knock down Tools for Transcription Factor 7-like-2 (TCF7L2) and Evaluation of its Expression Pattern in Developing Chicken Optic Tectum,” published just last year in MicroRNA.

We’ll get right to the reason — the retraction note provides one short one:

Continue reading Mystery conflict between authors fells molecular bio paper

Neuroscience journal retracts paper for lack of “scientific soundness”

Screen Shot 2016-03-03 at 9.21.12 AMAn unusual article that considered the concept of change from a systems perspective — including change in medicine, economics, and decision-making, for instance — has, well, changed from “published” to “retracted.”

After commenters on PubPeer called the 2014 paper “gibberish” and even suggested it might be computer-generated, Frontiers in Computational Neuroscience retracted it, noting it “does not meet the standards of editorial and scientific soundness” for the journal, according to the retraction notice. The paper’s editor and author maintain there was nothing wrong with the science in the paper.

Here’s the full note for “Sensing risk, fearing uncertainty: systems science approach to change:” Continue reading Neuroscience journal retracts paper for lack of “scientific soundness”

NFL and NYT collide: Did studies on concussion rates leave out necessary data?

National Football LeagueThe National Football League failed to include data from diagnosed concussions in peer-reviewed studies, making the sport look safer than it is, allege the results of an investigation published yesterday in the New York Times. Now, the paper and the NFL are arguing over whether the studies were supposed to include every instance of head injury.

Early studies on concussion rates published in the journal Neurosurgery left out at least 100 instances of of concussions, the Times reported. The Times and the NFL disagree on the implications of studies based on an incomplete data set: Sources told the Times that it’s bad science, while the NFL explains that the studies were “necessarily preliminary.”

Yesterday afternoon, the sports league published a statement saying that the Times story “is contradicted by clear facts” and “sensationalized.” The statement argued that:  Continue reading NFL and NYT collide: Did studies on concussion rates leave out necessary data?