Category: basic life sciences retractions

Images that raised eyebrows flagged by another journal; Malaysian gov’t investigates

Screen Shot 2016-06-15 at 9.17.15 AMMultiple investigations have been launched into allegations of blatant duplications by a research group in Malaysia.

Last week, users alleged on Twitter that three papers by the same team included pictures of cells that were copied and pasted. First author Nima Samie, affiliated with University of Malaya in Malaysia, denied the accusations — but both the Malaysian government and now two journals sees cause for further investigation.

Frontiers in Pharmacology published an expression of concern this morning:

Continue reading Images that raised eyebrows flagged by another journal; Malaysian gov’t investigates

Fraudster loses third attempt to remove 7-year debarment

court caseA U.S. judge has denied a virology researcher’s third attempt to overturn a seven-year debarment from receiving federal funds, following a 2010 decision by the U.S. Office of Research Integrity.

The ORI banned Scott Brodie for seven years after concluding he had committed 15 acts of misconduct at the University of Washington. The deception affected grant applications, published papers, manuscripts, and presentations. Since then, Brodie has tried multiple times to reverse the ruling in court.

In the latest decision, dated June 13, United States District Judge James E. Boasberg writes: Continue reading Fraudster loses third attempt to remove 7-year debarment

Misidentified cell line fells cancer paper

Screen Shot 2016-04-15 at 2.52.06 PMResearchers have retracted a paper about a new molecular target for cancer after realizing they had mistaken the identity of their cell line.

It’s all too easy to mix up cell lines, so we see plenty of retractions for that reason — and, according to an expert in the area, many more cases lurk uncorrected in the literature.

The retraction notice for “Knockdown of tumor protein D52-like 2 induces cell growth inhibition and apoptosis in oral squamous cell carcinoma” in Cell Biology International explains the authors’ perspective on this case:

Continue reading Misidentified cell line fells cancer paper

Columbia investigation reveals researcher faked data — and a degree

InnateImmunityA researcher faked data and a masters degree, according to an investigation by Columbia University.

He’s also earned his fourth retraction. The new notice, along with one we’ve uncovered from 2014, provide some information on the extent of the deception of Robert Frumento, who left Columbia a decade ago, around the time that the now-retracted papers were published.

Here’s the new retraction notice:

Continue reading Columbia investigation reveals researcher faked data — and a degree

Author denies accusations of blatant duplication

NPGTwitter is abuzz today over allegations that a recent paper in Scientific Reports contains a blatant example of duplication.

According to the allegations, a group of researchers in Malaysia have used the same four images to represent some 30 cells at different stages of cell death. One researcher has even suggested the allegedly doctored images appear in three different papers.

Is this a manipulated image? See for yourself:

Continue reading Author denies accusations of blatant duplication

Pharmacology journal pulls paper for “insufficient scientific quality;” authors disagree

Frontiers in PharmacologyAgainst the authors’ wishes, a pharmacology journal has retracted a paper after receiving two messages questioning the “soundness of the experimental results.”

The editors of the journal, Frontiers in Pharmacology, issued an expression of concern about the paper in April 2016, and investigated it following the allegations. According to the retraction notice, the authors disagree with the retraction.

Here’s the retraction notice for the paper: Continue reading Pharmacology journal pulls paper for “insufficient scientific quality;” authors disagree

PLOS ONE retracts 2 malaria papers over doubts experiments ever took place

PLOS One

Authors have retracted a pair of PLOS ONE papers after an investigation suggested the articles might contain some fiction.

In the papers, the authors describe collecting and analyzing the DNA of mosquitoes to look for changes following the introduction of bed nets treated with insecticides to combat malaria. However, an investigation by the Institut de Recherche pour le Développement in France could not confirm some of the experiments ever took place.

Here’s the retraction notice for “How the Malaria Vector Anopheles gambiae Adapts to the Use of Insecticide-Treated Nets by African Populations,” which appears at the top of the paper:

Continue reading PLOS ONE retracts 2 malaria papers over doubts experiments ever took place

Pro-lifers call for JAMA to retract 2005 paper about fetal pain

JAMAPro-life activists have asked JAMA to retract a 2005 paper that suggested fetuses can’t feel pain before the third trimester.

Critics are arguing that newer findings have shown pain sensation appears earlier in gestation, yet the 2005 data continue to be cited in the discussion around abortion. What’s more, they note, some of the authors failed to mention their ties to the abortion industry.

The 2005 paper has been cited 191 times, according to Thomson Reuters Web of Science. We spoke with Howard Bauchner, Editor in Chief at JAMA and The JAMA Network, who told us something similar to what he said last week, when PETA asked to retract a paper they claim could be harmful to elephants: Continue reading Pro-lifers call for JAMA to retract 2005 paper about fetal pain

Prompted by PubPeer, biologist corrects three papers

GeneA biologist has corrected three papers that are nearly a decade old, after concerns were raised on PubPeer.

A commenter first posted a comment about an image in one of the papers in 2013; after more comments on other papers appeared in November 2015, author Zoya Avramova at the University of Nebraska-Lincoln received emails alerting her to the threads. She has responded, including to the 2013 comment, noting “the said images should have been assembled more carefully.”

After repeating some of the experiments to verify the results, she has now issued corrections on three papers, about the genetics of model organism Arabidopsis. The papers share a first author, Abdelaty Saleh, who was a postdoc in Avramova’s lab at the time of the work.

The correction notice for “Dynamic and stable histone H3 methylation patterns at the Arabidopsis FLC and AP1 loci,” appearing in the July 2016 volume of Gene, explains:  Continue reading Prompted by PubPeer, biologist corrects three papers

Authors reused images in three papers, concludes journal probe

JBCBiologists are retracting three papers after the journal concluded they contain reused images, designed to represent different experiments. The authors stand by the conclusions, some of which they say have been “extensively validated.”

The Journal of Biological Chemistry used image analysis software to evaluate the images, first published at least a decade ago. Unfortunately, the raw data behind the problematic images were not available. The authors have also corrected a fourth paper in another journal, and wrote on PubPeer that they are working with journals to address concerns in three more.

The papers share two authors: Mireia Duñach at the Autonomous University of Barcelona, and Antonio García de Herreros at the Institut Hospital del Mar d’Investigacions Mèdiques. A representative of the Institut Hospital del Mar d’Investigacions Mèdiques told us it is looking into Garcia de Herreros’s work.

We’ll start with “β-Catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to β-catenin,” which has been cited 45 times since it was published in 2002, according to Thomson Reuters Web of Science. The retraction notice says:

Continue reading Authors reused images in three papers, concludes journal probe