Category: basic life sciences retractions

Huh? Cancer paper gets retracted because of its correction

Here’s a rather odd case: When readers raised issues about some of the images in a 2008 cancer paper, the authors issued a correction last year. But when readers asked additional questions about the corrected images, the authors decided to retract the paper entirely, along with its correction.

Both the original and corrected versions were questioned on PubPeer.

Here’s the retraction notice for the 2008 article “PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2,” published in Oncogene, which includes a link to the July 2016 correction: Continue reading Huh? Cancer paper gets retracted because of its correction

15-year old paper pulled for image problems

A group of researchers in France has been forced to retract their 2002 article in the Journal of Virology after learning that the paper was marred by multiple image problems.

The paper, “P0 of Beet Western Yellows Virus Is a Suppressor of Posttranscriptional Gene Silencing,” came from the lab of Veronique Ziegler-Graff, a plant biologist at the University Louis Pasteur, in Strasbourg. The authors attribute some of the image problems to “genuine mounting mistakes,” and have repeated the experiments to confirm the conclusion, as have other labs. However, the researchers couldn’t find all the original data from the 2002 paper.

Although the retraction statement points the finger at the first author, Sebastien Pfeffer, the list of contributors includes Patrice Dunoyer, a frequent collaborator of Olivier Voinnet, a high-profile plant biologist whose work has come under intense scrutiny.

According to the lengthy notice:
Continue reading 15-year old paper pulled for image problems

“Knowledgeable informant” outs researchers for falsifying data

A pathology journal has retracted a 2015 paper from researchers in China after concluding the authors had falsified and copied some of the data and text.

According to the notice, a “knowledgeable informant” told the journal about the overlap and “fraudulent” aspects of the paper, which the editors were able to confirm. The journal retracted the paper last month.

Here’s the retraction notice for “Genistein attenuates glucocorticoid-induced bone deleterious effects through regulation Eph/ephrin expression in aged mice:”

Continue reading “Knowledgeable informant” outs researchers for falsifying data

Cancer researcher has dodged accusations for decades (and has a new correction)

Today isn’t a great day for Carlo Croce, chair of the department of cancer biology and genetics at The Ohio State University (OSU).

The New York Times has a lengthy article detailing the misconduct accusations that have swirled around Croce for years. We’ve covered many, but The Gray Lady obtained documents that show there have been many more.

The story mentions a 2013 letter from Ohio State University to pseudonymous whistleblower Clare Francis (which we reported on in 2014), acknowledging Francis’s allegations against Croce. However, in the letter, an administrator said OSU saw no reason to investigate Croce.

The story didn’t stop there, as the Times reports:

Continue reading Cancer researcher has dodged accusations for decades (and has a new correction)

Author says he lied about approval for animal research

A researcher in South Korea has retracted a 2015 paper after telling the journal he falsified the institutional approval required to conduct the animal experiments.

In the article, the author explicitly says that the Animal Experiment Review Board of a university based in Seoul, South Korea approved the experiments, but according to the journal, “the author did not receive an approval by the board and he used a false approval number.”

Here’s the retraction notice for “The role of compensatory movements patterns in spontaneous recovery after stroke,” published in the Journal of Physical Therapy Science (JPTS) in September 2015 and retracted in December: Continue reading Author says he lied about approval for animal research

3rd retraction appears for fired Pfizer breast cancer researcher

Pfizer has retracted a paper by a former employee who was fired after the company discovered she had been doctoring data.

The retraction, in Molecular Cancer Research, is the third of five papers Pfizer asked to retract, after an investigation discovered they contained duplicated images. The papers have been discussed on PubPeer, which is also mentioned in the latest retraction notice.

As a result of the investigation, Pfizer terminated the employment of Min-Jean Yin, the last author on the newly retracted paper.

According to the notice, Yin and five of her co-authors agreed to the retraction:

Continue reading 3rd retraction appears for fired Pfizer breast cancer researcher

Researcher who lost whistleblower lawsuit logs 4 more retractions

A brain journal has retracted four papers by a researcher due to image duplications that the university uncovered during an investigation into his work.

According to the retraction notice, Wayne State University found that Christian Kreipke had used several images in these articles “to represent different results in grant proposals and/or poster presentations,” and that the data were unreliable. Kreipke now has a total of five retractions, by our count.

As we’ve reported before, Wayne State and Kreipke have been engaged in conflict for several years. In 2012, Kreipke was dismissed from his assistant professor post at Wayne State after the university said it found evidence of research misconduct, according to Courthouse News. Kreipke fired back against the university, filing a whistleblower lawsuit. In it, Kreipke claimed that the institution was “involved in a conspiracy,” according to unsealed court documents, in which it had swindled the U.S. government out of millions in research funding.

A judge dismissed the case in 2014, but the conflict between Kreipke and Wayne State was not over. Continue reading Researcher who lost whistleblower lawsuit logs 4 more retractions

Unexplained abnormalities in stem cells prompt Columbia researchers to pull diabetes paper

Researchers at Columbia University have retracted a 2013 paper in The Journal of Clinical Investigation, after uncovering abnormalities in the stem cell lines that undermined the conclusions in the paper.

Last year, corresponding author Dieter Egli discovered he could not reproduce key data in the 2013 paper because almost all the cell lines first author Haiqing Hua used contained abnormalities, casting doubt on the overall findings. When Egli reached out to Hua for answers, Hua could not explain the abnormalities. As a result, Hua and Egli agreed the paper should be retracted.

Since some of the details of how the paper ended up relying on abnormal cells remain unclear, the university confirmed to us that it is investigating the matter.

Here’s the retraction notice for “iPSC-derived β cells model diabetes due to glucokinase deficiency,” cited 42 times: Continue reading Unexplained abnormalities in stem cells prompt Columbia researchers to pull diabetes paper

Neuroscientist flags errors in his days-old paper “for the sake of science integrity”

Only days after his paper was published online, a neuroscientist has posted a comment on PubMed alerting readers to several duplication errors.

Despite the issues, which the researcher says were introduced into the final manuscript after peer review, he reassured readers that they do not influence the final conclusions in the paper.

On February 9, ten days after the article came online, corresponding author Garret Stuber at the University of North Carolina at Chapel Hill wrote a detailed comment on PubMed Commons, explaining that the “research community” had brought four figure-related errors to his attention. After investigating the concerns, Stuber discovered that the problems emerged after the peer-review process, “while revising the manuscript to comply with Nature Neuroscience’s final formatting guidelines.” In his note, he outlined the specific duplication issues that arose, which he says he plans to detail to the journal in a formal corrigendum letter.

Stuber alerted the scientific community about his PubMed comment via Twitter: Continue reading Neuroscientist flags errors in his days-old paper “for the sake of science integrity”

Former postdoc admitted to fraud in cell bio paper, lead author says

A researcher in Switzerland has retracted her 2015 paper in the Journal of Cell Biology, saying the first author — her former postdoc — admitted to fabricating multiple aspects of the paper.

After Sophie Martin of the University of Lausanne couldn’t reproduce the data from another manuscript she was preparing to submit, she contacted her former student, Pranav Ullal, who admitted he had fabricated the data, along with two figures in the JCB paper.

A spokesperson for the University of Lausanne told us that Ullal left Switzerland after his contract was over, and is now in India.

Martin told us the whole experience has been upsetting:

Continue reading Former postdoc admitted to fraud in cell bio paper, lead author says