When 1 equals 2, the result is a retraction

bmcrnA group of psychiatric researchers in Norway has lost their 2013 paper in BMC Research Notes on the effects of antipsychotic medications on the brain after discovering that they’d botched their imaging analyses.

The article, “Does changing from a first generation antipsychotic (perphenazin) to a second generation antipsychotic (risperidone) alter brain activation and motor activity? A case report,” came from a trio of scientists at the University of Bergen and Haukeland University Hospital, also in Bergen. According to the abstract of the paper, which was published last May:

Continue reading When 1 equals 2, the result is a retraction

Authors withdraw already-corrected JBC paper questioned on PubPeer

jbc 8-9-13An assistant professor of neuroscience at Tufts has withdrawn a paper published last year after one round of corrections wasn’t enough to fix all of the study’s problems.

The study, “Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein,” by Gizem Donmez and colleagues, had already been subject to an extensive correction in May: Continue reading Authors withdraw already-corrected JBC paper questioned on PubPeer

Penkowa notches fourth retraction, in Experimental Neurology

exp neuroMilena Penkowa, the Danish neuroscientist who resigned from the University of Copenhagen in December 2010 amid suspicions of misconduct, has had another paper retracted.

The new retraction appears in Experimental Neurology. Here’s the notice for “M-CSF deficiency leads to reduced metallothioneins I and II expression and increased tissue damage in the brain stem after 6-aminonicotinamide treatment”: Continue reading Penkowa notches fourth retraction, in Experimental Neurology

Neural Networks retracts rerun

neuralnetworksIrony alert: If you’re going to write articles about recurrent neural networks, make sure they don’t, well, recur.

The journal Neural Networks has retracted a 2012 paper by a group of researchers from Spain for publishing what amounted to a repeat of a 2011 article in a different but closely related journal. Scientific publishing, alas, is not like Hollywood, where remakes of movies and TV shows is not only acceptable, it seems to be the only flavor producers are willing to taste.

The article was titled “Hopf Bifurcation Stability in Hopfield Neural Networks” — Hopf, for those keeping score at home, is Eberhard Hopf, a famous (and politically controversial) mathematician and founder of something called ergodic theory — and it came from scientists at the University of La Laguna, in the Canary Islands.

According to the notice: Continue reading Neural Networks retracts rerun

“Major error” forces retraction of ghrelin study

Try as we may, we can’t cover every retraction in real time. But on the principle that late is better than later, here’s one from 2012 that we’ve been meaning to get to.

neuroreportThe journal NeuroReport has retracted a 2011 article by a group of researchers who evidently discovered a fatal flaw in one of their figures.

The article, “Ghrelin prevents neuronal apoptosis and cognitive impairments in sepsis-associated encephalopathy,” by a team of intensivists from Zhejiang University in Hangzhou, China, purported to find that ghrelin, which stimulates appetite, appeared to have something of a protective effect against the ravages of sepsis in rat brains. It has been cited three times, according to Thomson Scientific’s Web of Knowledge, including once by the retraction.

As the abstract stated: Continue reading “Major error” forces retraction of ghrelin study

Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

jneuroscicoverThe Journal of Neuroscience has retracted a 2012 paper by a group from Sweden’s Karolinska Institutet for what appears to be research misconduct. But more on that in a moment.

The article, “The Existence of FGFR1-5-HT1A Receptor Heterocomplexes in Midbrain 5-HT Neurons of the Rat: Relevance for Neuroplasticity,” came from the lab of Kjell Fuxe, whose interests include Parkinson’s disease, addiction and depression. The first and second authors, Dasiel Oscar Borroto-Escuela and Wilber Romero-Fernandez, are listed as being post-docs in the lab.

According to the notice: Continue reading Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

“Serious irregularities” in Western blots lead to retraction of brain chemistry paper

jneuroscijuly13The Journal of Neuroscience has retracted a 2009 article by a group from Mount Sinai (now the Icahn School of Medicine at Mount Sinai) for suspicious Western blots.

The paper, “Requirement for Protein Synthesis at Developing Synapses,” came from the lab of Deanna Benson, a Parkinson’s expert. According to the abstract, which is still available on the journal’s website:

Continue reading “Serious irregularities” in Western blots lead to retraction of brain chemistry paper

Retractions arrive for former Wash U neuroscience grad student found to have committed misconduct

Adam Savine
Adam Savine

Two studies by Adam Savine, the former Washington University neuroscience graduate student found by the Office of Research Integrity to have falsified data, have been retracted.

Here’s the notice for one: Continue reading Retractions arrive for former Wash U neuroscience grad student found to have committed misconduct

Autism genetics papers retracted after fraud inquiry at NY research agency

GBBcoverA fraud investigation at a New York state research institution has led to two retractions of papers looking at genetic links to autism.

The 2011 papers, which appeared in Genes, Brain and Behavior, involve work conducted at the New York State Office for People With Developmental Disabilities’ (OPWDD’s) Institute for Basic Research in Developmental Disabilities, on Staten Island. The last author on both articles is Xiaohong Li, head of the institute’s cellular neurobiology laboratory.

Bitter legal fight leads to a retracted retraction

faseb june 2013Two years ago, the FASEB Journal retracted a paper that it had initially agreed to correct, after a dean at one of the author’s institutions said that a “well-recognized and top-class fact finding commission concluded that the publication contains gross flaws.” The retraction of the 2003 paper, as we noted at the time, punctuated a complicated case involving several investigations as well as legal maneuvering.

Now, the journal has retracted the retraction. Here’s the beginning of the notice: Continue reading Bitter legal fight leads to a retracted retraction