Category: molecular biology

Dev Cell paper retracted after author admits to doctoring data

Developmental CellThe authors of a Developmental Cell paper have retracted it after the first author admitted to manipulating and falsifying data and reagents.

The problems came to light after the authors couldn’t reproduce the findings, about a mechanism underlying meiosis. When questioned about the matter, the first author of the paper, Saurav Malhotra, admitted to doctoring data and materials. 

Here’s the retraction notice to the paper, “The Anaphase-Promoting Complex/Cyclosome Is Essential for Entry into Meiotic M-Phase:” Continue reading Dev Cell paper retracted after author admits to doctoring data

After painful retraction, authors republish replicated findings five years later

chembiochemIt was one of the most difficult posts we’ve ever written: A researcher’s eagerness to publish a paper before asking all co-authors for their permission forced him to retract the article, wasting a postdoc’s time and destroying a professional relationship in the process.

This 2011 post wasn’t difficult to write because the facts were complex; they weren’t particularly (although the science involved was intricate). Rather, the man responsible for the incident, Graham Ellis-Davies, was so clearly and sincerely distressed by the mistake he’d made, it was impossible not to feel sorry for the him.

Well, we’re delighted to report that the tale has a happy ending. Ellis-Davies and his former postdoc have recently republished their once-retracted work with a new set of co-authors — and in the same journal that previous retracted it. What’s more, they have turned what initially was a proof-of-concept study into a much more robust article with exciting implications for the field.  Continue reading After painful retraction, authors republish replicated findings five years later

Duke researcher adds another retraction in JCI, bringing count to 15

JCIWe’ve found another retraction for Erin Potts-Kant, a former researcher at Duke, bringing her total to 15.

Yesterday we reported on two new retractions for Potts-Kant in PLoS ONE, which earned her a spot in the top 30 on our leaderboard. As with the others, the latest paper, in the Journal of Clinical Investigation, is marred by “unreliable” data.

Here’s the retraction notice for “In utero supplementation with methyl donors enhances allergic airway disease in mice“:

Continue reading Duke researcher adds another retraction in JCI, bringing count to 15

Duke pulmonary researcher up to 14 retractions, putting her on our leaderboard

PLOS OneA pair of Duke researchers who each have more than 10 retractions have earned some more.

Both of the newly retracted papers — originally published in 2012 by PLOS ONE — list Erin Potts-Kant as a co-author; one includes her former supervisor, Michael Foster, as lead author. The pair has since left Duke (Potts-Kant was arrested for using school credit cards to shop at the likes of Target, and Foster retired). The reason provided for these retractions will be familiar to anyone who’s been following their case — there were “concerns about the reliability” of the data.

By our count, Potts-Kant now has 14 retractions, making her one of the few women to hold a position on our leaderboard.

Here’s the retraction notice for “Iron Supplementation Decreases Severity of Allergic Inflammation in Murine Lung,” a paper that lists both Foster and Potts-Kant as authors:

Continue reading Duke pulmonary researcher up to 14 retractions, putting her on our leaderboard

Oops — journal published same paper three times

surface interface analysisOn November 25, 2014, a journal published an article on mass spectrometry. Then on December 18th they published it again — twice.

Yes: “Mass analysis by Ar-GCIB-dynamic SIMS for organic materials” was mistakenly published a total of three times.

Over a year later, the journal pulled the two redundant publications. Here’s the retraction notice for one of them:

Continue reading Oops — journal published same paper three times

Biologists earn 5th retraction following Swedish investigation

plos pathA team of biologists have earned a fifth retraction for a paper containing manipulated images, following an investigation by the Swedish government.

Last year, the investigation found that former Uppsala University doctoral student Apiruck Watthanasurorot had manipulated figures in five papers, four of which have already been retracted. Earlier this year, we reported that his supervisor, last author Kenneth Söderhäll, had requested PLOS Pathogens simply correct the fifth paper because independent groups have confirmed the findings. But according to the retraction notice for “Bacteria-Induced Dscam Isoforms of the Crustacean, Pacifastacus leniusculus,” Söderhäll has since agreed to the retraction:

Continue reading Biologists earn 5th retraction following Swedish investigation

Cancer paper that doctored image from Science story earns retraction

lungcancercoverHere’s a joke for all you middle-schoolers out there. How are doctored images like bad pennies? They keep cropping up!

Here’s the latest one we’ve picked up: Lung Cancer has retracted a 2014 paper on the genetics of tumors after concluding the authors cribbed a figure that had appeared in a 2005 feature story in Science.

The paper, “ß-elemene against human lung cancer via up-regulation of P53 protein expression to promote the release of exosome,” drew attention on PubPeer last September from a reader who noticed striking similarities between one of the images the authors used and a figure in the Science piece (subscription required). According to the PubPeer commenter: Continue reading Cancer paper that doctored image from Science story earns retraction

Stem cell researchers fix two papers following PubPeer comments

Screen Shot 2016-04-13 at 5.56.09 PMA pair of stem cell researchers have earned two corrections, the result of images that were mislabeled, distorted, or compiled incorrectly, according to the notices.

Kang Cheng prepared the gels when he was a research fellow in last author Sanjeev Gupta‘s lab at the Albert Einstein College of Medicine. Gupta told us he reviewed the original gels, and the errors didn’t affect the conclusions in the papers, which were reproducible. He noted he believes the problems are the result of honest mistakes:

The errors did not confer any benefits whatsoever either for the papers or for Dr. Cheng.

On PubPeer, commenters have raised questions about the now corrected papers — along with several others on which Gupta is the senior author, but Cheng is not a co-author.

Edward Burns, research integrity officer at Einstein, told us that the medical school looked into an allegation of misconduct against Gupta:  

Continue reading Stem cell researchers fix two papers following PubPeer comments

Team in Japan earns third retraction for misconduct

JSRA team of researchers has earned its third retraction after an investigation at Oita University in Japan found instances of misconduct in their research.

The most recent notice mentions the investigation, and specifies that the first author, Satoshi Hagiwara, was responsible for the problematic figures in the paper. Hagiwara is also the first author on two retracted papers we reported on last year; one of the earlier retractions also mentions the investigation, but does not assign responsibility to any particular author. All three papers share three authors.

The retraction notice for “Continuous Hemodiafiltration Therapy Ameliorates LPS-Induced Systemic Inflammation in a Rat Model,” published in the Journal of Surgical Research, explains the issues with the paper:

Continue reading Team in Japan earns third retraction for misconduct

Authors correct highly cited biology paper due to “genuine mistake”

Journal of Cell ScienceAuthors of a highly cited biology paper in the Journal of Cell Science (JCS) have corrected the data underlying one of the figures.

The 2003 paper, “The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors,” has been cited 566 times, according to Thomson Reuters Web of Science. One of the authors is the last author on a recent high profile retraction from Nature Genetics, which cost the first author a grant from the European Molecular Biology Organisation.

The correction note tells us a bit more: Continue reading Authors correct highly cited biology paper due to “genuine mistake”