Nature yanks controversial genetics paper whose co-author was found dead in lab in 2012

naturecover1113Nature has retracted a controversial 2012 paper by a group from Johns Hopkins University which has been the subject of a protracted public dispute.

The article, “Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK,” came from the lab of Jef Boeke,  a celebrated biochemist. But a former lab member, Daniel Yuan, who was fired by Hopkins in late 2011 after 10 years at the institution, had repeatedly raised questions about the validity of the findings. Those concerns eventually made their way into the Washington Post, prompting this response from the university. Continue reading Nature yanks controversial genetics paper whose co-author was found dead in lab in 2012

“Personal rivalry” leads to retraction of nut-health paper

ejpcHere’s a retraction that leaves us itching to know more:

The authors of a recent paper in the European Journal of Preventive Cardiology on nut intake and the risk of high blood pressure and diabetes have pulled their article from publication for an undisclosed conflict of interest.

Now, you wouldn’t know this unless you were willing to pony up the $32 to read the notice, which is behind a pay wall — something that drives us, well, nuts. But here it is:

Continue reading “Personal rivalry” leads to retraction of nut-health paper

Two detailed retraction notices correct the cardiology record

jaccTwo American College of Cardiology conference abstracts published earlier this year in the Journal of the American College of Cardiology (JACC) have been retracted, one because the authors were actually measuring something other than what they reported, and the other because newer software invalidated the results.

Here’s the notice for “Worsening of Pre-Existing Valvulopathy With A New Obesity Drug Lorcaserin, A Selective 5-Hydroxytryptamine 2C Receptor Agonist: A Meta-Analysis of Randomized Controlled Trials” by Hemang B. Panchal, Parthav Patel, Brijal Patel, Rakeshkumar Patel, and Henry Philip of East Tennessee State University: Continue reading Two detailed retraction notices correct the cardiology record

Henry IV, part 2: No retraction necessary, say some authors of royal head identification paper

Henry IV, via Wikimedia
Henry IV, via Wikimedia

Last week, we reported that some of the authors of a 2010 paper in the BMJ claiming to have identified Henry IV’s head thought the study should be retracted based on new evidence. Some of the other authors have now responded to that call for retraction, which appeared on the BMJ’s site alongside the paper.

Philippe Charlier, the corresponding author of the original paper, and five of the original paper’s 15 co-authors conclude after reviewing the evidence that

Continue reading Henry IV, part 2: No retraction necessary, say some authors of royal head identification paper

Chopping broccoli: Researchers lose paper on florets after readers raise questions

b&mclWith apologies to Dana Carvey, Bioorganic & Medicinal Chemistry Letters has chopped a 2012 paper on the molecular constituents of broccoli florets after readers evidently were forced to do the job of reviewers and point out fatal flaws in the study.

The article, “Two novel bioactive glucosinolates from Broccoli (Brassica oleracea L. var. italica) florets,” came from a group in South Korea and has yet to be cited, according to Thomson Scientific’s Web of Knowledge. But according to the retraction notice, after publication critics pointed out serious problems with the work. To wit: Continue reading Chopping broccoli: Researchers lose paper on florets after readers raise questions

JBC issues correction for paper by Khachigian, who has had four others retracted

jbc1113The Journal of Biological Chemistry has a fairly gory correction — we’d call it a mega-correction — for a 2010 paper by Levon Khachigian, an Australian researcher whose studies of a new drug for skin cancer recently were halted over concerns about possible misconduct, including image manipulation. As we reported earlier this year, Khachigian has already lost four papers, including one in the JBC — which the journal simply noted had “been withdrawn by the authors.”

The new correction involves the article “c-Jun regulates shear- and injury-inducible Egr-1 expression, vein graft stenosis after autologous end-to-side transplantation in rabbits, and intimal hyperplasia in human saphenous veins,” which Khachigian wrote with Jun Ni and Alla Waldman. The paper has been cited nine times, according to Thomson Scientific’s Web of Knowledge. Here’s the notice: Continue reading JBC issues correction for paper by Khachigian, who has had four others retracted

Irony alert: Forensic experts have paper retracted for plagiarism

ijmbrTime to roll out the irony meter again.

A group of scientists from Uttar Pradesh, India, who study forensic bioinformatics have had a paper retracted for something that can generally be detected with a specialized form of forensic software: Plagiarism.

Here’s the notice for Kumar Ajay, Singh Neetu, Gaurav S.S. “Forensic Bioinformatics: An innovative technological advancement in the field of Forensic Medicine and Diagnosis,” signed by O.A. Sofola, editor-in-chief: Continue reading Irony alert: Forensic experts have paper retracted for plagiarism

No, math prof, Google isn’t a proper literature search (and don’t plagiarize your dead mentor)

semigroupSometimes, it’s easiest and most straightforward if we just let retraction notices sink in before we comment on them.

Take this one from Semigroup Forum, signed by Chong-yih Wu of National Pingtung Institute of Commerce, Pingtung, Taiwan: Continue reading No, math prof, Google isn’t a proper literature search (and don’t plagiarize your dead mentor)

Retraction for authors of muscle paper who lifted data from their own 18-year-old article

janatFor the second time in a week, we’ve seen a journal retract a paper because it duplicated something in its own archive. Yesterday, it was a case of plagiarism in a plant journal. Today, we find that the Journal of Anatomy has retracted an article it published earlier this year by a group of Slovenian authors who took a page (or several) out of their 1995 article in the same periodical.

The article, “Muscles within muscles: a tensiomyographic and histochemical analysis of the normal human vastus medialis longus and vastus medialis obliquus muscles,” came from researchers in the department of orthopedic surgery at the University Medical Centre in Ljubjana. According to the abstract: Continue reading Retraction for authors of muscle paper who lifted data from their own 18-year-old article

He said, she said: Journal of Neuroscience expresses concern, but doesn’t pursue investigation

j neuroscienceThe Journal of Neuroscience‘s retraction notices often give us plenty to chew on, and a new Expression of Concern does the same.

In the notice — for a 16-year-old paper — the journal notes three cases of what certainly sounds like image manipulation, but carefully avoids calling it that: Continue reading He said, she said: Journal of Neuroscience expresses concern, but doesn’t pursue investigation