Dodgy figure in cord blood paper prompts Expression of Concern in oncology journal

cmionccoverThe editor of Clinical Medicine Insights: Oncology has issued an Expression of Concern over a 2008 paper by a group of authors in China after identifying “flaws” in one of the figures.

The article, “Exvivo experiments of human ovarian cancer ascites-derived exosomes presented by dendritic cells derived from umbilical cord blood for immunotherapy treatment,” purported to show that:

tumor-specific antigens present on exosomes can be presented by DCs [dendritic cells] derived from unrelated umbilical cord blood to induce tumor specific cytotoxicity and this may represent as a novel immunotherapy for ovarian cancer.

But according to William C. S. Cho, editor of the journal, there’s reason to doubt the conclusions. As the notice explains:
Continue reading Dodgy figure in cord blood paper prompts Expression of Concern in oncology journal

Cell reviewing allegations of image reuse in human embryonic stem cell cloning paper

cell cloningCell is looking into whether the authors of a widely hailed study published last week claiming to have turned human skin cells into embryonic stem cells manipulated images inappropriately, Retraction Watch has learned.

The potential image problems came to light on PubPeer, a site designed to allow for post-publication peer review. A commenter, identified as Peer1, identified “several examples of image reuse which might be of interest to PubPeer members and readers:” Continue reading Cell reviewing allegations of image reuse in human embryonic stem cell cloning paper

Update: Microbiologists face two more retractions for Northern blot problems

microbiologyWe have an update on a case we reported last week involving four papers in two different journals. The Journal of Bacteriology retracted two papers by Carlos Barreiro and colleagues, in notices that referred to the fact that

…identical bands for the 16S rRNA probe controls in the Northern blots were reported to correspond to experiments using different strains and experimental conditions in articles published in this journal and in Microbiology over a period of 5 years…

We checked with the editor of Microbiology, Agnes Fouet, who tells us: Continue reading Update: Microbiologists face two more retractions for Northern blot problems

Two Journal of Bacteriology papers retracted for data duplication spanning five years

j bacteriolA group of bacteria researchers in Spain and Germany has lost two papers in the Journal of Bacteriology after the journal found evidence that they had reused figures.

The two notices, for “Heat Shock Proteome Analysis of Wild-Type Corynebacterium glutamicum ATCC 13032 and a Spontaneous Mutant Lacking GroEL1, a Dispensable Chaperone” and “Transcriptional Analysis of the groES-groEL1, groEL2, and dnaK genes in Corynebacterium glutamicum: Characterization of Heat Shock-Induced Promoters,” say the same thing: Continue reading Two Journal of Bacteriology papers retracted for data duplication spanning five years

Retraction for image issues forces correction of herbal remedies editorial

jmm mayBack in March, we wrote about the case of Chinese researchers who pulled their 2011 paper in the Journal of Molecular Medicine on ginseng’s potential as a heart remedy because a couple of their images were suspect (duplicated was the word they’d used).

Turns out the journal suffered some collateral damage. JMM also has corrected a “Clinical Implications” article by a group of Canadian researchers about the defunct ginseng paper.

The article, “Use of ginseng to reduce post-myocardial adverse myocardial remodeling: applying scientific principles to the use of herbal therapies,”  appeared in the same issue as the original, but for some reason the correction notice appeared online only last week.

It states: Continue reading Retraction for image issues forces correction of herbal remedies editorial

Two Expressions of Concern in Blood for MD Anderson’s Aggarwal, who has threatened to sue Retraction Watch

aggarwalBharat Aggarwal, the MD Anderson researcher who has threatened to sue us while under investigation by his institution for alleged misconduct, now has two Expressions of Concern in addition to two corrections and two unexplained withdrawals.

Both of the papers were published in Blood. The Expression of Concern for “Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-κB signaling pathway,” reads: Continue reading Two Expressions of Concern in Blood for MD Anderson’s Aggarwal, who has threatened to sue Retraction Watch

Diabetes paper retracted for “misgrouping errors” that remain under investigation

diabetesA group of researchers at the University of Minnesota have retracted a paper in Diabetes for image problems, but exactly what happened is still under investigation.

Here’s the notice: Continue reading Diabetes paper retracted for “misgrouping errors” that remain under investigation

Streisand Effect meets tough editors as journal retracts already-corrected paper by Rui Curi

curiRui Curi — the Brazilian scientist who threatened to sue the now-shuttered Science-Fraud.org site for criticizing his work — has rung up his second retraction, this one for a paper that he corrected earlier this year.

Here’s the Journal of Endocrinology notice, whose headers and language are a bit confusing, understandably, because it is retracting two things, a correction and the original paper: Continue reading Streisand Effect meets tough editors as journal retracts already-corrected paper by Rui Curi

Two cancer papers retracted because authors “are unable to guarantee the accuracy of some of the figures”

cancer lettersA team of researchers in Ireland has retracted two papers from Cancer Letters after concerns were apparently raised about some of the studies’ figures.

Denise Egan, of the Institute of Technology Tallaght in Dublin, and colleagues published “In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines” and “A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells” in 2007.

The two notices say the same thing: Continue reading Two cancer papers retracted because authors “are unable to guarantee the accuracy of some of the figures”

Two retractions appear for former Harvard dental researcher found to have committed misconduct

Martin
Martin Biosse-Duplan

Martin Biosse-Duplan, a former Harvard dental school research fellow found by the Office of Research Integrity to have falsified results has had the two papers in question retracted.

From the Journal of Bone and Mineral Research: Continue reading Two retractions appear for former Harvard dental researcher found to have committed misconduct