NIH/Harvard team loses aging study to manipulated data

agecoverAge has retracted a 2012 article by a group of scientists from the National Institutes of Health and Brigham and Women’s Hospital in Boston after an NIH inquiry turned up evidence of data manipulation in the work.

The article, “Aging decreases rate of docosahexaenoic acid synthesis-secretion from circulating unesterified α-linolenic acid by rat liver,” came from the lab of Stanley Rapoport, chief of the brain physiology and metabolism section of the National Institute on Aging.

As the abstract explained: Continue reading NIH/Harvard team loses aging study to manipulated data

Nature corrects a correction

nature 4 9 14Last year, we reported on a Nature correction of a paper for what a McGill University committee had earlier called “intentionally contrived and falsified” figures. It turns out that the correction — like the original paper — left some Nature readers puzzled, so the journal has run a correction of the correction: Continue reading Nature corrects a correction

Fraud fells Alzheimer’s “made to order” neurons paper in Cell

cell414In 2011, a group of researchers at Columbia University reported in Cell that they had been able to convert skin cells from patients with Alzheimer’s disease into functioning neurons — a finding that raised the exciting prospect of “made to order” brain cells for patients with the degenerative disease. As one researcher not involved with the study, led by Asa Abeliovich, put it:

“[This is] simply a remarkable and complete piece of work which will now set a standard for stem cell work in neurological disease. The standard of the characterization of the neuronal cultures is very high,” John Hardy at University College London, U.K., wrote to [Alzforum]. He was not involved in the work but is taking a similar approach in his own lab.

According to the abstract of “Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons:”

Continue reading Fraud fells Alzheimer’s “made to order” neurons paper in Cell

Pain study retracted for bogus data is second withdrawal for University of Calgary group

molpainBack in January 2013, we wrote about the retraction of a paper in Diabetes that the authors had “submitted without knowledge of inherent errors or abnormalities that they recognized in retrospect after submission.”

Now, Molecular Pain has retracted a paper by the same authors, this time for data manipulation. The article, “Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states,” was written by Cory Toth, a clinical neuroscientist at the University of Calgary, in Canada, and colleagues. It has been cited eight times, according to Thomson Scientific’s Web of Knowledge.

Toth said of the Diabetes article at the time:
Continue reading Pain study retracted for bogus data is second withdrawal for University of Calgary group

Bogus Western blots lead to retraction of cancer paper

ejpharmA group of Italian researchers has retracted their 2013 paper on colorectal cancer because one of the authors, they, say, was tinkering with the data.

The article, “PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines,” appeared in the European Journal of Pharmacology in August. The first author was Giuseppina Gangemi, of the University of Salerno.

The paper purported to find that:

Continue reading Bogus Western blots lead to retraction of cancer paper

“I am deeply saddened and disturbed:” Co-author of retracted Nature paper reveals how problems came to light

Ben Scheres
Ben Scheres

On Wednesday, we reported on a Nature retraction of a paper whose corresponding author had also had a Cell paper retracted, and had been found to have committed a “violation of academic integrity” by Utrecht University. Today, we present the back story of how those retractions came to be, from another co-author of both papers, Ben Scheres, of Wageningen University: Continue reading “I am deeply saddened and disturbed:” Co-author of retracted Nature paper reveals how problems came to light

Authors of controversial STAP stem cell study author correct 2011 paper

tissue engineering aThere have been a number of developments in the unraveling of two Nature studies out of the RIKEN Institute in Japan and Harvard purporting to show an easy way to create stem cells. There was an interim report of RIKEN’s investigation last Friday, and more details emerged this week.

And today, the Japan Times reported that last week, a correction of a 2011 paper by many of the same authors appeared in Tissue Engineering Part A. Here’s the correction notice, dated March 13: Continue reading Authors of controversial STAP stem cell study author correct 2011 paper

Nature paper by researcher found to have violated academic integrity retracted

dhonukshe
Pankaj Dhonukshe

A 2013 paper in Nature that was among those whose first or last author had committed a “violation of academic integrity,” according to Utrecht University, has been retracted.

Here’s the notice: for “CLASP-mediated cortical microtubule organization guides PIN polarization axis,” whose corresponding author was Pankaj Dhonukshe: Continue reading Nature paper by researcher found to have violated academic integrity retracted

SK Sahoo notches sixth retraction

am&IChemist Sanjeeb Kumar Sahoo, of the Institute of Life Sciences in Bhubaneswar, India, has earned his sixth retraction for image shennanigans, this time in Applied Materials & Interfaces.

Sahoo, as we reported last year, had lost five articles in Acta Biomaterialia  for what the journal called “highly unethical practices.”

The latest retraction involves an article titled “Composite Polymeric Magnetic Nanoparticles for Codelivery of Hydrophobic and Hydrophilic Anticancer Drugs and MRI Imaging for Cancer Therapy,” which first appeared online in 2011 in AM&I, a publication of the American Chemical Society.

The paper has been cited 40 times, according to Thomson Scientific’s Web of Knowledge. According to the abstract: Continue reading SK Sahoo notches sixth retraction

Not-so-tiny ethics issues as Micron retracts first-ever paper, and authors apologize for five duplicates

micronThe editors of the journal Micron — an Elsevier title — have retracted its first paper ever, and in an editorial marking the occasion, take on a number of issues in scientific publishing misconduct.

The beginning of the editorial (which is paywalled): Continue reading Not-so-tiny ethics issues as Micron retracts first-ever paper, and authors apologize for five duplicates