Category: faked data

A bullshit excuse? My lab notebook “was blown into a manure pit”

CleanA researcher who studies how to turn dairy cattle manure into natural gas falsified and fabricated data in a journal article and failed to declare a commercial conflict of interest, a Washington State University investigation has found.

The study “Evaluation of Co-Digestion at a Commercial Dairy Anaerobic Digester” was published in 2011 in the journal CLEAN: Soil, Air, Water. First author Craig Frear was a Ph.D. student at WSU Pullman when the study was carried out and an assistant professor at the time of the investigation. The editor-in-chief of CLEAN, Prisca Henheik, told us that the retraction is a done deal even though it has not been posted online: Continue reading A bullshit excuse? My lab notebook “was blown into a manure pit”

Nature retracts paper six years after it was flagged for fraud

cover_natureNature retracted a paper on protein structures today, six years after an investigation at the University of Alabama identified several structures that were “more likely than not falsified and/or fabricated” by one of the authors.

The paper came under scrutiny soon after it was published in 2006. A letter published in Nature that same year pointed out “physically implausible features in the structures it described.” That triggered the investigation at the University of Alabama, the result of which was published in 2009, identifying “nine publications related to the same protein structures that should be retracted from various scientific journals.” Everything was pinned on last author H.M. Krishna Murthy, who the investigation determined was “solely responsible for the fraudulent data.”

A 2009 Nature news article on the investigation declared that the “fraud is the largest ever in protein crystallography.”

We’re not sure what took Nature so long to retract the letter, titled “The structure of complement C3b provides insights into complement activation and regulation.” Here’s the note, which explains that not all the authors agreed to the retraction:

Continue reading Nature retracts paper six years after it was flagged for fraud

Third retraction appears for Leiden researcher fired in 2013

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A researcher who was fired from Leiden University Medical Center in 2013 for fraud has notched a third retraction, following an investigation by her former workplace.

When Leiden fired Annemie Schuerwegh, they announced two retractions of papers that contained manipulated data. This third retraction — the last, according to a spokesperson for the center  — is for “a discrepancy between the data reported in the article and the original collected data,” per the note.

The 2011 paper, “Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium” published in Arthritis Research & Therapy, suggests the source of a protein involved in rheumatoid arthritis. It has been cited 51 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction note:

Continue reading Third retraction appears for Leiden researcher fired in 2013

JAMA retracts osteoporosis paper with manipulated data

Screen Shot 2015-12-29 at 10.48.49 AMA JAMA study on an inexpensive treatment for osteoporosis has been retracted because the first author falsified or fabricated data. We’ve been expecting this one: An investigation at Women’s College Hospital in Toronto, the bone researcher’s former workplace, had already revealed issues with the paper.

An internal memo sent to staff (available in full here) in October explained that the investigation had found “unequivocal evidence of systematic data manipulation” by Sophie Jamal, who had already resigned from her positions at WCH and the University of Toronto.

The study appeared to show that nitroglycerin ointment could have a small positive effect on bone mineral density in postmenopausal patients. It’s been cited 30 times, according to Thomson Scientific’s web of Knowledge. (That’s two more times than when we last reported on the paper: It was cited once by the investigation, and once by a paper that was published earlier in October, but had not yet been indexed.)

Here’s the retraction note for “Effect of Nitroglycerin Ointment on Bone Density and Strength in Postmenopausal Women: A Randomized Trial:”

Continue reading JAMA retracts osteoporosis paper with manipulated data

Fifth retraction for Wayne State researcher who fudged figures

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Teresita L. Briones

Another retraction has appeared for Teresita Briones, who used to study neuroscience at Wayne State University — the final of five papers flagged by the Office of Research Integrity for containing falsified data.

According to the ORI notice published in May, Briones “intentionally, knowingly, and recklessly engaged in research misconduct by falsifying and/or fabricating data.” This latest paper to be retracted, which looks at the role of specific receptor in chronic inflammation of nervous tissue in rats, has two figures that “were duplicated, reused and falsely relabelled, and claimed to represent different experiments,” according to the retraction note.

The retraction note for “Chronic neuroinflammation and cognitive impairment following transient global cerebral ischemia: role of fractalkine/CX3CR1 signaling,” published in the Journal of Neuroinflammation, specifies the problematic figures:

Continue reading Fifth retraction for Wayne State researcher who fudged figures

Harper’s first-ever retraction is of a 1998 article by infamous fabricator Stephen Glass

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In the world of journalism, Stephen Glass is legendary — and not in a good way. For the first time in the 165-year-old magazine’s history, Harper’s is officially retracting a 1998 article by Glass, who was discovered to have made up quotes, people, and even entire stories.

Glass — whose deception was captured in the film “Shattered Glass” — actually requested the retraction for “Prophets and Losses,” in a letter to the editor published in the January 2016 issue of the magazine. He specifies the sections he fabricated, which Harper’s calculated affects “at least 5,647 of the 7,902 words” (more than 70 percent) of the article.

Now, as with the retractions for academic journals that we usually cover around here, Harper’s has affixed a note to the article:

Continue reading Harper’s first-ever retraction is of a 1998 article by infamous fabricator Stephen Glass

Authors retract abstract following misconduct by diabetes biotech

1Earlier this year, authors retracted a meeting abstract about a diabetes drug, following the revelation that the biotech that funded the trial committed misconduct.

The retraction was initiated by corresponding author Itamar Raz, at Hadassah Medical Center in Israel. The journal didn’t receive a response from any co-authors who were affiliated with the biotech company, Andromeda, so they were not included in the retraction process.

A few months after Hyperion Therapeutics acquired Andromeda’s diabetes drug DiaPep277, Hyperion announced it had evidence that some employees of Andromeda had “engaged in serious misconduct,” such as using un-blinded data and manipulating the analyses. Two relevant studies on the drug, designed to block the immune response that leads to type 1 diabetes, were retracted last year.

Here’s the retraction note for the abstract “Abstracts of the 50th Annual Meeting of the EASD, Vienna 2014. ‘Evaluation of DiaPep277® treatment in type 1 diabetes by integrated analysis,’” published in the May issue of the journal:

Continue reading Authors retract abstract following misconduct by diabetes biotech

Singapore investigation leads to two retractions, two more on the way

cov150hAuthors have retracted papers from Cell Metabolism and the Journal of Biological Chemistry after an investigation in Singapore found issues, including falsified data. The investigation is ongoing, and two additional retractions, along with two corrections, are on the horizon.

The investigation looked into papers by first authors Sudarsanareddy Lokireddy, now a postdoc at Harvard, and Sandhya Sriram, a postdoc at the Agency for Science, Technology and Research in Singapore. Led by the Nanyang Technological University in Singapore, where some of the work was done, the investigation concluded that there were issues with six papers on which either Sriram or Lokireddy was first author.

All authors but Lokireddy have agreed to retractions or corrections. Ravi Kambadur of NTU, and Mridula Sharma at the National University of Singapore, are the last two authors on all the papers.

According to a notice from the NTU, the “investigation found a number of instances of alterations to data” in three papers on which Lokireddy is first author. One of those was retracted December 1 by Cell Metabolism: Continue reading Singapore investigation leads to two retractions, two more on the way

7th retraction for heart researcher who faked patient records

1.coverAnna Ahimastos, a heart researcher who faked patient records, has notched her 7th retraction.

One more paper is expected to be retracted, according to a spokesperson from her former institution, the Baker IDI Heart & Diabetes Institute in Australia.

As with the other retractions, the 2005 paper in Hypertension — about how the hypertension drug ramipril may help alleviate cardiovascular disease — is being pulled after Ahimastos admitted to scientific misconduct. She asserts the data remain valid, and has not signed the retraction notice.

The Hypertension paper has been cited 63 times, according to Thomson Scientific’s Web of Knowledge. Here’s the retraction note in full (the language will be familiar to readers who have been following this case):

Continue reading 7th retraction for heart researcher who faked patient records

NSF investigating as more falsified results surface from mol bio researcher

Screen Shot 2015-12-04 at 5.22.53 PMAuthors of a paper on the origin and function of a family of transmembrane proteins have retracted it after an investigation at the University of Florida revealed that an author had falsified some results.

This is the third paper with falsifications that Chi Leung, a former UF postdoc, is responsible for; this summer, we reported on a retraction and a partial retraction of two other papers on which Leung was a co-author. The case is currently under investigation by the U.S. Office of Research Integrity National Science Foundation, a UF spokeswoman tells us.

The problems in the paper, “Phylogenetic, expression, and functional analyses of anoctamin homologs in Caenorhabditis elegans,” occur in a figure that compares mRNA levels in control and experimental populations of C. elegans. The paper was published in the American Journal of Physiology, and has been cited eight times, according to Thomson Scientific’s Web of Knowledge.

The retraction note explains that, according to the other authors, much of the data in the paper are valid:

Continue reading NSF investigating as more falsified results surface from mol bio researcher