Suspicions of data manipulation lead to correction of testicular cancer paper

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The corresponding author of a paper on testicular cancer is telling readers to discount a figure after she learned it may have been manipulated.

Although that one figure in the 2005 paper in the British Journal of Cancer may be problematic, the authors found data to support the other figures, and its conclusions.

This isn’t the first time first author Kerry Manton has faced questions over her data — in 2012, one of her papers was retracted following an investigation by her institution, the Queensland University of Technology. And in 2014, QUT repaid a $275,000 grant after finding Manton

failed to fulfill (her) responsibilities in relation to the responsible dissemination of research findings and that this, coupled with a failure to correct the errors, constituted research misconduct.

Here’s the corrigendum for “Hypermethylation of the 5′ CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis:”

Continue reading Suspicions of data manipulation lead to correction of testicular cancer paper

Four retractions follow Swedish government findings of negligence, dishonesty

242915_1uu_logoA Swedish ethical review board has censured two biologists and their employer, Uppsala University, for events related to “extensive image manipulations” in five papers published between 2010 and 2014. The case has led to criticism from an outside expert — who brought the allegations to Uppsala — over the current system in Sweden for handling such investigations.

Four of the papers have been retracted, and the authors have requested a correction in the fifth.

After an eight-month investigation, in September the government-run Expert Group for Scientific Misconduct at the Central Ethical Review Board in Stockholm, Sweden, concluded that Uppsala professor Kenneth Söderhäll — who has published more than 200 papers — and lecturer Irene Söderhäll acted “negligently” and “dishonestly” by Continue reading Four retractions follow Swedish government findings of negligence, dishonesty

Cancer study pulled when published without supervisor’s consent

turkish jThe Turkish Journal of Medical Sciences has retracted a paper after concerns surfaced from a researcher who claims to have supervised the research but was not listed as a co-author.

The first author completed the research — which explored the use of epigenetic alterations as potential early signs of cancer — as part of her master’s degree, under the supervision of Muy-Teck Teh at the Barts & The London School of Medicine & Dentistry. When Teh contacted the journal to say he had not consented to the publication, Ayesha Umair claimed she had paid for the research herself.

Here’s the retraction note for “Quantitative study of epigenetic signature in head and neck squamous cell carcinoma,” which tells us more about the dispute: Continue reading Cancer study pulled when published without supervisor’s consent

Neuroscience paper retracted after colleagues object to data publication

frontiersA paper published this October in the journal Frontiers In Neuroscience was retracted the following month because the authors’ collaborators did not give them permission to publish some of the data.

The paper detailed how and why the authors use the software program Nengo to test large simulations of nervous system networks. As part of the research, the authors tested five systems, one of which they were working on with another group. Due to a “miscommunication,” the authors thought they had received permission to publish the data; they plan to resubmit a paper describing the other four systems.

Here’s the official retraction note: Continue reading Neuroscience paper retracted after colleagues object to data publication

Author retracts statements about gay conversion therapy

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Key assertions in a paper on homosexuality have been removed from the Journal of the Islamic Medical Association of North America, in what the notice describes as a “partial retraction.”

The 2006 article “Homosexuality: An Islamic Perspective,” states that conversion therapy can be effective, and that gay people have poorer health. Those statements are among those that lack evidence, according to a note on the paper published in July. The retraction pulls those assertions, among others, and instead argues that a homosexual person should be helped to “accept his or her LGB identity,” and find a welcoming community.

The 2006 article is definitely a perspective — it states the opinion of the sole author, M. Basheer Ahmed, who has a private psychiatry practice in Texas, as to whether homosexuality is a choice. He thinks yes, though the science on the matter is fairly clear that it’s not.

But we still think it’s interesting that a journal chose to take back some of the statements contained in the article. Here’s the abstract from the “partial retraction” note:

Continue reading Author retracts statements about gay conversion therapy

Science flags immune-boosting paper under investigation

F1.mediumScience magazine has issued an expression of concern for a paper on the discovery of a new immune-boosting protein. The paper’s findings, which received some press coverage when they came out last spring, are now under investigation by Imperial College London.

The expression of concern follows a correction noting a Western blot mix-up. Science Editor in Chief Marcia McNutt told us last month that the mistake resulted from “carelessness” on the part of the authors. But now, an investigation at Imperial College London — where Philip Ashton-Rickardt led the research — is formally looking into the findings.

That investigation is ongoing, according to the expression of concern (signed by McNutt):

Continue reading Science flags immune-boosting paper under investigation

PLOS ONE issues editor’s note over controversial chronic fatigue syndrome research

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After a request for the original data was denied, PLOS ONE editors have flagged a 2012 sub analysis of a controversial clinical trial on chronic fatigue syndrome with an editor’s note.

The editor’s note — which reads like an Expression of Concern — reiterates the journal’s policy that authors make data and materials available upon request, and notes that staff are following up on “concerns” raised about the study.

There have been numerous requests for data from the “PACE” trial, as the clinical trial is known, which the authors say they have refused in order to protect patient confidentiality. On November 13, James Coyne, a psychologist at the University Medical Center, Groningen, submitted a request for the data from the PLOS ONE paper to King’s College London, where some of the authors were based. According to Coyne’s WordPress blog (he also has a blog hosted by PLOS), the journal asked him to let them know if he “had any difficulties obtaining the data.” He did — KCL denied the request last Friday (the whole letter is worth reading):

The university considers that there is a lack of value or serious purpose to your request. The university also considers that there is improper motive behind the request. The university considers that this request has caused and could further cause harassment and distress to staff.

Last author Peter White at Queen Mary University of London, UK, told us the journal had not asked them to release the data, but he would work with PLOS to address any questions:

We understand PLOS One are following up concerns expressed about the article, according to their internal processes. We will be happy to work with them to address any queries they might have regarding the research.

Here’s the editor’s note for “Adaptive Pacing, Cognitive Behaviour Therapy, Graded Exercise, and Specialist Medical Care for Chronic Fatigue Syndrome: A Cost-Effectiveness Analysis,” in full:

Continue reading PLOS ONE issues editor’s note over controversial chronic fatigue syndrome research

Paper claiming extra CO2 doesn’t always lower plant nutrients pulled for errors

11Authors have retracted a large meta-analysis claiming that rising levels of carbon dioxide don’t always reduce nutrients in plants.

After commenters on PubPeer raised concerns, the authors say they found several unintentional errors in their data that could “significantly change conclusions” of the paper in Plant Ecology, according to the retraction note.

The paper found that the impact of rising CO2 depends on many factors — in some cases, extra amounts of this greenhouse gas could actually increase plant nutrients. Trouble is, some of the papers that cited the now-retracted article came to the opposite conclusion: Increased carbon dioxide levels do decrease plant nutrients.

The retraction note for “CO2 effects on plant nutrient concentration depend on plant functional group and available nitrogen: a meta-analysis” explains some of the specifics of the errors, and says that there was “no evidence of bias:”

Continue reading Paper claiming extra CO2 doesn’t always lower plant nutrients pulled for errors

Management researcher with 7 retractions issues “clarifications” to 2013 paper

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The authors of a paper on supportive supervisors just want readers to “better understand the reported findings,” and so have issued multiple “clarifications” in a corrigendum note.

Some of the issues addressed in the note have been raised on PubPeer.

The paper’s author list includes one Fred Walumbwa, formerly an Arizona State University management researcher, some of whose work has succumbed to scrutiny in the the past two years. His current list: seven retractions, a megacorrection, an expression of concern, and now this.

Unraveling the relationship between family-supportive supervisor and employee performance,” published in Group & Organization Management, has been cited twice, according to Thomson Scientific’s Web of Knowledge.

Here’s the note in full:

Continue reading Management researcher with 7 retractions issues “clarifications” to 2013 paper

Study claiming dramatically higher rates of male military sexual trauma is retracted

psychological servicesA study that found a 15-fold increase in the rate of sexual trauma among men in the U.S. military — and sparked suggestions of “an epidemic of male-on-male sex crimes” in the military among conservative media outlets — has been retracted because of a flaw in the analysis.

The study, published just last week, appeared in Psychological Services, an American Psychological Association (APA) journal. In an announcement Sunday titled “American Psychological Association Retracts Article Positing Excessively High Rates of Sexual Trauma Among Military Men,” the APA said that “Scholars raised valid concerns regarding the design and statistical analysis which compromise the findings.” Here’s the text: Continue reading Study claiming dramatically higher rates of male military sexual trauma is retracted