Why publishing negative findings is hard

Jean-Luc Margot
Jean-Luc Margot

When a researcher encountered two papers that suggested moonlight has biological effects — on both plants and humans — he took a second look at the data, and came to different conclusions. That was the easy part — getting the word out about his negative findings, however, was much more difficult.

When Jean-Luc Margot, a professor in the departments of Earth, Planetary & Space Sciences and Physics & Astronomy at the University of California, Los Angeles, tried to submit his reanalysis to the journals that published the original papers, both rejected it; after multiple attempts, his work ended up in different publications.

Disagreements are common but crucial in science; like they say, friction makes fire. Journals are inherently disinterested in negative findings — but should it take more than a year, in one instance, to publish an alternative interpretation to somewhat speculative findings that, at first glance, seem difficult to believe? Especially when they contain such obvious methodological issues such as presenting only a handful of data points linking biological activity to the full moon, or ignore significant confounders?

Margot did not expect to have such a difficult experience with the journals — including Biology Letters, which published the study suggesting that a plant relied on the full moon to survive: Continue reading Why publishing negative findings is hard

Investigation leads to 5th retraction for drug researcher

Screen Shot 2016-01-26 at 6.05.21 PMA pharmaceutical researcher has received his fourth and fifth retractions for duplicating papers.

Last we saw Giuseppe Derosa on this blog, he was notching retractions after publishing results from the same clinical trial in six different papers; as part of that fallout, a journal has pulled a fourth paper associated with the trial.

Here’s the note for “Effects of an olmesartan/amlodipine fixed dose on blood pressure control, some adipocytokines and interleukins levels compared with olmesartan or amlodipine monotherapies,” which has been cited twice, according to Thomson Scientific’s Web of Knowledge:  Continue reading Investigation leads to 5th retraction for drug researcher

You’ve been dupe’d: Meet authors who like their work so much, they publish it twice

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When our co-founders launched the site in 2010, they wondered whether there would be enough retractions to write about on a regular basis. Five+ years and three full-time staffers later, and we simply don’t have the time to cover everything that comes across our desk.

In 2012, we covered a group of duplication retractions in a single post, simply because duplications happen so frequently (sadly) and often don’t tell an interesting story. So in the interest of bookkeeping, we’re picking up the practice again.

Here are five unrelated retractions for your perusal: all addressing duplications, in which the same – or mostly the same – authors published the same – or mostly the same – information in two different – or sometimes the same – journals.

So, on the buffet table we offer the following entrees: Continue reading You’ve been dupe’d: Meet authors who like their work so much, they publish it twice

Wiley published a biology paper in the wrong journal

Screen Shot 2016-01-04 at 2.47.07 PMWiley Periodicals is withdrawing a biochemistry paper after mistakenly publishing it in the wrong journal.

The mistake took a few months to sort out.  Wiley initially published “Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages” online in Journal of Cellular Physiology in May of last year. The article was posted in the correct journal — Journal of Cellular Biochemistry — in July.

At the very end of 2015, the publisher officially withdrew the version it posted in the Journal of Cellular Physiology.

Here’s the withdrawal note (which is paywalled — tsk, tsk):

Continue reading Wiley published a biology paper in the wrong journal

Data dispute forces journal to pull paper about rare bird on valuable land

coverThe authors of a paper about the density of an endangered bird on valuable Texas lands are disputing the journal’s decision to pull the paper after other scientists objected to some of its contents.

The paper, published online in August by the Journal of Field Ornithology, compared different models for estimating the number of golden-cheeked warblers that nest in Texas. According to the Austin American-Statesman, some of that land includes highly sought-after woodlands. Developers had used estimates from recent years, which suggested that the bird population was in relatively good health, to petition to open that land for real estate development. But the new paper concluded that those estimates were too high.

After some scientists who produced the more rosy estimates claimed that the some of their data had been included in the newest paper without permission, the editor in chief decided to retract it.

That was in November. There’s no retraction note for “Density influences accuracy of model-based estimates for a forest songbird.” We contacted the editor in chief, Gary Ritchison, to ask why. He told us,

Continue reading Data dispute forces journal to pull paper about rare bird on valuable land

New developments cause authors to pull paper on drugs’ environmental impact

integrated envThe authors of an article about the effects of pharmaceutical drugs on the environment have retracted it before publishing the final version due to new developments in the field, which would have required a major revision.

The authors pulled the paper from Integrated Environmental Assessment and Management before it went through the final publication process – such as copyediting and proofreading – after they learned about new findings related to assessing to the risks of human exposures to pharmaceuticals in the environment.

We’d try to figure out which portions of the paper might need updating, but publisher Wiley recently pulled the original article and abstract, against the journal editor’s wishes.

Here’s the retraction note: Continue reading New developments cause authors to pull paper on drugs’ environmental impact

The Big (Retraction) Short: Securitized loans paper may get change of venue

J financeA paper on the securitized loan industry’s pricing practices was pulled from the Journal of Finance, but may be appearing in another journal.

The Journal of Finance issued a notice of withdrawal, for “Who Facilitated Misreporting in Securitized Loans?” by John M. Griffin and Gonzalo Maturana, but does not say why it was taken out.  Griffin’s web site notes that the paper is to be published in the Review of Financial Studies.

Here’s the note, dated Sept. 23: Continue reading The Big (Retraction) Short: Securitized loans paper may get change of venue

A bullshit excuse? My lab notebook “was blown into a manure pit”

CleanA researcher who studies how to turn dairy cattle manure into natural gas falsified and fabricated data in a journal article and failed to declare a commercial conflict of interest, a Washington State University investigation has found.

The study “Evaluation of Co-Digestion at a Commercial Dairy Anaerobic Digester” was published in 2011 in the journal CLEAN: Soil, Air, Water. First author Craig Frear was a Ph.D. student at WSU Pullman when the study was carried out and an assistant professor at the time of the investigation. The editor-in-chief of CLEAN, Prisca Henheik, told us that the retraction is a done deal even though it has not been posted online: Continue reading A bullshit excuse? My lab notebook “was blown into a manure pit”

Singapore investigation leads to two retractions, two more on the way

cov150hAuthors have retracted papers from Cell Metabolism and the Journal of Biological Chemistry after an investigation in Singapore found issues, including falsified data. The investigation is ongoing, and two additional retractions, along with two corrections, are on the horizon.

The investigation looked into papers by first authors Sudarsanareddy Lokireddy, now a postdoc at Harvard, and Sandhya Sriram, a postdoc at the Agency for Science, Technology and Research in Singapore. Led by the Nanyang Technological University in Singapore, where some of the work was done, the investigation concluded that there were issues with six papers on which either Sriram or Lokireddy was first author.

All authors but Lokireddy have agreed to retractions or corrections. Ravi Kambadur of NTU, and Mridula Sharma at the National University of Singapore, are the last two authors on all the papers.

According to a notice from the NTU, the “investigation found a number of instances of alterations to data” in three papers on which Lokireddy is first author. One of those was retracted December 1 by Cell Metabolism: Continue reading Singapore investigation leads to two retractions, two more on the way

Authors lied about ethics approval for study on obesity, depression

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Obesity has retracted a study that suggested overweight people may be less depressed than their slimmer counterparts in cultures where fat isn’t stigmatized, after realizing the authors lied about having ethical approval to conduct the research.

The authors claimed their research protocol had been approved by Norwegian and Bangladeshi ethical committees, but, according to the retraction note, part of the study “was conducted without the required approval of the university ethics board.” The journal’s managing editor told us that there is no evidence that there was harm to the study subjects.

Here’s more from the retraction note for “In Bangladesh, overweight individuals have fewer symptoms of depression than nonoverweight individuals:”

Continue reading Authors lied about ethics approval for study on obesity, depression