Biologists delete paper from literature after realizing they’d deleted too many genes

Researchers deleted more genes than they bargained for in a Drosophila strain, a mistake that resulted in a retraction of a paper from 2007.

Ron Wides, a biologist specializing in pattern development at Bar-Ilan University, Israel, and colleagues have retracted a paper published in Mechanisms of Development after his lab found that their technique to delete the Ten-a gene ended up deleting other nearby genes, too.

It was deletions of other genes, and not Ten-a, that killed the fruit flies, Wides concluded. His group had also concluded, erroneously, that Ten-a is what’s known as a “pair-rule” gene. Fruit fly embryos develop in stacked segments, like tubes of Pringles; pair-rule genes guide the development of alternating segments. Those other loci, and not Ten-a, caused lethality and caused the flies to develop improperly early,  Wides concluded.

The retraction reads in full: Continue reading Biologists delete paper from literature after realizing they’d deleted too many genes

Korean stem cell investigation expands to another researcher, and more papers

Last month, we brought you the story of Soo-Kyung Kang, a Seoul National University stem cell researcher who has now retracted four papers amidst questions about image manipulation in a total of 14 studies. That story has drawn a great deal of attention in Korea, with comparisons to the Woo-Suk Hwang scandal, and has even led to a profile of Retraction Watch in the Seoul Daily, one of Korea’s largest newspapers.

We’ve now learned that the investigation has grown to 25 papers after an anonymous whistleblower warned about possible data fabrications in another paper by Kang, an associate professor of veterinary biotechnology, and Kyung-Sun Kang, director of the Adult Stem Cell Research Center in the same department (but no relation). And Soo-Kyung Kang was investigated in 2010, according to the Korea Herald.

The researchers’ labs are also under lockdown Continue reading Korean stem cell investigation expands to another researcher, and more papers

Former Millennium Villages Project staffer responds to critical Nature editorial

courtesy Nature

Last week, we wrote about a correction of a heavily criticized paper in The Lancet by the Millennium Villages Project, a large aid program. Paul Pronyk, director of monitoring and evaluation at Columbia University’s Center for Global Health and Economic Development, which runs the Project, left his job shortly after writing an explanatory letter that accompanied the correction.

That correction had come after a letter to The Lancet, but also after Nature had raised issues in an editorial. Nature’s editorial concluded: Continue reading Former Millennium Villages Project staffer responds to critical Nature editorial

Premature delivery? Paper on rapid assay for ruptured placenta pulled for “mishandling” of tests

The other day we brought you the story (well, not quite a STORY) of a group of researchers who had to retract a paper in the Journal of Computational Chemistry because of a “computation error.” We still don’t know what that means.

That was fresh in our minds when we came across the following retraction notice in the Journal of Obstetrics and Gynaecology Research: Continue reading Premature delivery? Paper on rapid assay for ruptured placenta pulled for “mishandling” of tests

Computational chem journal retracts article for, um, computation error

If you’re going to publish in the Journal of Computational Chemistry, it probably makes sense to have one’s computer tuned up for the task.

Or else you might wind up like a group of researchers in China who had to endure this misfortune: Continue reading Computational chem journal retracts article for, um, computation error

Psychologists take a gamble on using data about risky behavior, and are forced to retract a paper

When the first sentence of a science paper reads like this, you might think you’re in for quite a ride:

Jumping out of an airplane may seem like a crazy and scary thing to do, but for a skydiver it is a fun and exciting experience.

Unfortunately for the authors of an earlier version of that paper comparing gamblers and skydivers, published in 2011 in the Scandinavian Journal of Psychology, the ride was short-lived, according to a retraction notice just published: Continue reading Psychologists take a gamble on using data about risky behavior, and are forced to retract a paper

‘Molecular characterization’ errors lead to retraction from medicinal chemistry journal

The European Journal of Medicinal Chemistry has published a curious retraction notice for a paper in its February 2012 issue from a group of Indian scientists.

The abstract of the article,”Proton-pumping-ATPase-targeted antifungal activity of cinnamaldehyde based sulfonyl tetrazoles,” is still available on Medline:

Here’s what the abstract of the paper said about the study: Continue reading ‘Molecular characterization’ errors lead to retraction from medicinal chemistry journal

Millennium Villages Project forced to correct Lancet paper on foreign aid as leader leaves team

A senior member of a high-profile foreign aid research team has left the project on the heels of a Lancet correction of a heavily criticized paper the team published earlier this month.

Paul Pronyk, who until last week was director of monitoring and evaluation at Columbia University’s Center for Global Health and Economic Development, which runs the Millennium Villages Project, wrote a letter to the Lancet acknowledging errors in the paper, “The effect of an integrated multisector model for achieving the Millennium Development Goals and improving child survival in rural sub-Saharan Africa: a non-randomised controlled assessment,” originally published May 8. That admission came after Jesse Bump, Michael Clemens, Gabriel Demombynes, and Lawrence Haddad wrote a letter criticizing the work, which was published this week accompanied by corrections to the paper: Continue reading Millennium Villages Project forced to correct Lancet paper on foreign aid as leader leaves team

An Immunity retraction for Luk van Parijs, three years after the ORI found evidence of fabrication in the paper

Earlier this month, we reported on a correction by Luk van Parijs, the biologist the Massachusetts Institute of Technology (MIT) fired in 2005 after he admitted to making up data.

Immunity has now run a retraction involving van Parijs, dated May 25, 2012, for 2003’s “Autoimmunity as the Consequence of a Spontaneous Mutation in Rasgrp1”: Continue reading An Immunity retraction for Luk van Parijs, three years after the ORI found evidence of fabrication in the paper

Not for the faint of heart: Cardiologists retract syncope paper after realizing data columns weren’t aligned right

Improperly aligned columns have cost researchers at the Mayo Clinic a paper in the Journal of the American College of Cardiology.

The paper originally concluded that fainting spells (syncope) give patients with high blood pressure in their lung arteries poor prognoses, an observation that turned out to be incorrect.

The problem? The group merged two electronic databases, but did not align columns properly, a problem found only after first author Rachel Le revisited the dataset looking to cull more data.

The retraction notice published on May 22 (the one on ScienceDirect is free to air, while the one on the JACC site is behind a paywall): Continue reading Not for the faint of heart: Cardiologists retract syncope paper after realizing data columns weren’t aligned right