Two groups mistakenly publish case reports on the same patient

Journal of Clinical Pharmacy and Therapeutics

Talk about a popular patient: A woman who developed a case of internal bleeding while taking the anticoagulant Xarelto (rivaroxaban) was written up in not one — but two — case reports. The trouble was, both groups didn’t realize what the other was doing, so the more recent article is now being retracted from the Journal of Clinical Pharmacy and Therapeutics.

The authors, a trio of doctors at Sakarya University in Turkey, described the case of a 75 year-old woman who came to the emergency room for fatigue and stomach pain after taking rivaroxaban for three days. A scan revealed a rectus sheath hematoma.

However, the case had already been published a few months earlier in the Indian Journal of Pharmacology by a separate group of doctors from Sakarya, along with authors from Yenikent State Hospital and Vakfikebir State Hospital.

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Investigation of prominent geneticist Latchman finds “procedural matters,” no misconduct

David Latchman, Birkbeck

An investigation by the University College London has cleared prominent geneticist David Latchman of misconduct, but concluded he has “procedural matters in his lab that required attention.”

Latchman has two retracted paperson PubPeer, there are questions about nearly four dozen more.

The results of the investigation were first reported by the Times Higher Education. We also received a short statement from a UCL spokesperson:

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“Our manuscript unintentionally failed to meet academic and publication standards”

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Authors of a 2014 review paper about the use of “as needed” medications by people with mental health diagnoses are retracting it, but we’re scratching our heads as to why.

The retraction appears in “The experiences of mental health professionals’ and patients’ use of pro re nata (PRN) medication in acute adult mental health care settings: a systematic review protocol of qualitative evidence,” published by The JBI Database of Systematic Reviews and Implementation Reports.

From the abstract of the paper:

Pro re nata is a Latin phrase meaning “for an unforseen need or contingency”…The authors of the systematic review found that although the practice of using “as required” medication is common there is no good evidence of whether this is the best way of helping people to be less agitated when compared to being given a regular dose of medication.

We’re not entirely sure what went wrong here. This is the full contents of the note:

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Yes, many psychology findings may be “too good to be true” – now what?

scienceToday, Science published the first results from a massive reproducibility project, in which more than 250 psychology researchers tried to replicate the results of 100 papers published in three psychology journals. Despite working with the original authors and using original materials, only 36% of the studies produced statistically significant results, and more than 80% of the studies reported a stronger effect size in the original study than in the replication. To the authors, however, this is not a sign of failure – rather, it tells us that science is working as it should:

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Three retractions for Oregon neuroscience student investigated by ORI

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Journals have retracted three out of the four papers flagged by the Office of Research Integrity during its investigation of a University of Oregon neuroscience student, David Anderson.

Last month, when we first reported on the case, Anderson told us that he “made an error in judgment,” and took “full responsibility.” Two of the retraction notes say that Anderson “knowingly falsified data,” and cited the Office of Research Integrity case summary.

All three papers focus on memory.

The note for the first retraction, from the  Journal of Experimental Psychology: Human Perception and Performance, reveals exactly how Anderson falsified data in the paper. It’s paywalled — tsk, tsk — but printed here in full:
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First author refuses to sign PNAS retraction after “key findings” are not reproduced

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Two out of the three authors of a PNAS paper on mutations underlying lung diseases are pulling it after failing to reproduce key findings.

The paper, published in 2012, investigated how mutations in lung surfactant genes induce molecular changes that lead to lung pulmonary fibrosis and lung cancer might work. But follow-up work revealed problems. In the retraction note, last author Christine Kim Garcia and second author Christoper Cano, both at the University of Texas Southwestern Medical Center, write:

Current members of the C.K.G. laboratory are unable to reproduce key findings reported in the paper.

Here’s the retraction note in full:

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Diederik Stapel ups count to 55 retractions

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Diederik Stapel

Dutch social psychologist and well-known fraudster Diederik Stapel is up to 55 retractions. He remains secure in his spot at #4 on our leaderboard.

The “fraudulent” Social Cognition article found, according to its abstract, that the more positively you perceive yourself, the less you need to compare yourself to other people. Conversely, negative thoughts were linked to more comparison to others. As an article in the New York Times points out, where Stapel’s faulty studies often succeeded is in telling us what we want to believe about the world.

Here’s the retraction note for the article:

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Former UCSF grad student fudged data in two papers

ORIA former graduate student at the University of California, San Francisco “knowingly falsified and/or fabricated” data in two published papers, according to the Office of Research Integrity.

According to a case summary published this morning, Peter Littlefield was working on his PhD, studying the ways that cells respond to external signals, when he published the two problematic papers. He is the first author on the papers; Natalia Jura, whose lab he worked in, is the last on both.

The report’s findings are based on, among other sources, “the respondent’s admission.”

The first paper, “Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations” was published in Science Signaling and has been cited twice, according to Thomson Scientific’s Web of Knowledge.

Three figures in the paper are problematic, says the ORI summary:

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Sea squirt draft paper published by mistake

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A paper on the evolution and development of urochordata — also known as sea squirts — was published in an under-developed form: Due to the publishers’ “error,” a “preliminary draft” of the article was published online in Developmental Dynamics last year.

The draft has been retracted; we can no longer find it on the site at all. The final copy of the paper has been posted in its place.

Here’s the retraction note in full for “Development, Metamorphosis, Morphology and Diversity: Evolution of Chordates muscles and the Origin of Vertebrates”:

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Paper on narcissistic CEOs earns big correction

home_coverIt may not be much of a surprise that narcissistic CEOs of pharmaceutical companies will make bold choices, such as adopting radically new technology. That idea remains true, despite a lengthy correction to a paper that supports it.

The paper, “CEO Narcissism, Audience Engagement, and Organizational Adoption of Technological Discontinuities,” in Administrative Science Quarterly, found support for the following hypothesis:

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