Investigation raises questions about top cancer researcher’s work

Journal of Pathology

A prominent pancreatic cancer researcher has lost a meeting abstract and corrected a Nature paper following an institutional investigation.

Queen Mary University of London determined that, in an abstract by Thorsten Hagemann, “elements of the study summarised by this abstract are not reliable.” Hagemann has recently issued a correction to a 2014 Nature paper he co-authored, which also cited the Queen Mary University of London (QMUL) investigation, noting there was reason to question the provenance of the data.

Hagemann is currently the medical director of Immodulon Therapeutics, and has long been recognized for his work in the field, including a three-year grant of £180,000 from the Pancreatic Cancer Research Fund in 2013.

Here’s the retraction notice from the The Journal of Pathology, regarding an abstract from the 7th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland: Continue reading Investigation raises questions about top cancer researcher’s work

Do publishers add value? Maybe little, suggests preprint study of preprints

ArXiv

Academic publishers argue they add value to manuscripts by coordinating the peer-review process and editing manuscripts — but a new preliminary study suggests otherwise.

The study — which is yet to be peer reviewed — found that papers published in traditional journals don’t change much from their preprint versions, suggesting publishers aren’t having as much of an influence as they claim. However, two experts who reviewed the paper for us said they have some doubts about the methods, as it uses “crude” metrics to compare preprints to final manuscripts, and some preprints get updated over time to include changes from peer-reviewers and the journal.

The paper, posted recently on ArXiv, compared the text in over 12,000 preprint papers published on ArXiv from February 2015 to their corresponding papers published in journals after peer review.

The authors report in their paper, “Comparing published scientific journal articles to their pre-print versions:” Continue reading Do publishers add value? Maybe little, suggests preprint study of preprints

Plagiarism, plagiarism, plagiarism: Five recent cases

RW logoThere’s so much publishing news to report, we don’t always get to cover every retraction when it appears. To get the word out more quickly, sometimes we publish a group of papers pulled for similar reasons, such as duplications. Below, we present five recent cases of plagiarism, such as using text or figures that the authors didn’t originally write.

We’ve added the date of retraction where we could find it:
Continue reading Plagiarism, plagiarism, plagiarism: Five recent cases

Authors retract PNAS paper suggesting silk stabilizes vaccines

PNASA PNAS paper that caught the media’s attention for suggesting that adding silk could stabilize vaccines and antibiotics has been pulled after the authors realized there were significant errors in the data analysis. 

According to the notice, the authors agreed to retract the 2012 paper; however, the corresponding author told us the authors did not think a retraction was required as, according to him, the conclusions remained valid.

The paper presented a solution to the long-standing problem that sensitive biological compounds such as vaccines and antibiotics begin to lose their effectiveness outside the recommended temperature range, and naturally biodegrade over time. The degradation process cannot be reversed, and may even speed up during transport or storage under less ideal temperatures.

Here’s the retraction notice: Continue reading Authors retract PNAS paper suggesting silk stabilizes vaccines

Authors pull Nature paper about DEET and flies

Nature CoverAuthors have retracted a Nature paper which identified neurons that render flies sensitive to a potent insect repellent, after losing confidence in the findings. The first author, however, said she does not agree with the retraction, noting that she continues to believe the data are correct.

According to the notice, the remaining authors say they no longer support the claim that certain neurons in the antennae of fruit flies are repelled by DEET, the active ingredient in many insect repellents. The last author told us some of the paper’s results are not in doubt; nevertheless, he added, the paper would not have been published in Nature without the key conclusion, so he and most of his co-authors have pulled the paper in its entirety.

Alongside the retraction, the journal has also published a Brief Communications Arising article by scientists who were unable to reproduce the paper’s findings.

Here’s the retraction notice, published today:
Continue reading Authors pull Nature paper about DEET and flies

JAMA: No plan to pull elephant-cancer risk paper after PETA protest

JAMAJAMA has decided not to retract an article about cancer risk in elephants after receiving a request to do so from an animal rights group.

People for the Ethical Treatment of Animals (PETA) recently protested the 2015 paper, which found that higher levels of a tumor suppressor gene could explain why elephants have a lower risk of cancer. According to PETA, the paper contained inaccurate information that could be used to justify inhumane treatment of elephants. At the time, the journal told us it considers all calls for retraction.

In an email sent to a representative of PETA over the weekend, Howard Bauchner, Editor in Chief at JAMA and The JAMA Network, wrote: Continue reading JAMA: No plan to pull elephant-cancer risk paper after PETA protest

Highly cited cancer researcher logs 8th, 9th retractions

Bharat Aggarwal
Bharat Aggarwal

Bharat Aggarwal, a highly cited cancer researcher who retired last year from MD Anderson, has logged two retractions following an investigation into his work, bringing his total to nine.

Aggarwal has threatened to sue us in the past, and told us that MD Anderson has been investigating his work. Earlier this year, Biochemical Pharmacology retracted seven studies of which he is the only common author, noting the “data integrity has become questionable.” Now, he’s earned two more retractions in Molecular Pharmacology, both for “inappropriate” or “unacceptable” image manipulation.

Both of the notices are paywalled (tsk, tsk). Here’s one for “Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells:” Continue reading Highly cited cancer researcher logs 8th, 9th retractions

Coptic cop-out? Religion journal won’t pull paper based on bogus ‘gospel’

HTR107_02What the Harvard Theological Review giveth, it evidently will not taketh away.

The venerable publication about religious matters is refusing to retract a 2014 article by a noted scholar of early Christianity despite evidence that the article — about Jesus’s wife — was based on a forgery.

The paper, by Harvard theologian Karen King, described a Coptic papyrus called “The Gospel of Jesus’s Wife,” which, among other things, includes language that suggests Christ was married: Continue reading Coptic cop-out? Religion journal won’t pull paper based on bogus ‘gospel’

Journal flags paper over allegations it used competitors’ text, plasmids

MGGA journal has issued an expression of concern (EOC) for a paper on a common crop virus after the authors were accused of using competitors’ unpublished text and plasmids.

Investigations by the journal and the involved institutions — the University of the Witwatersrand in South Africa, where the paper’s authors are based, and North Carolina State University (presumably, where the accusing group is from) — were inconclusive, the notice states.

So the editor flagged “Sequences enhancing cassava mosaic disease symptoms occur in the cassava genome and are associated with South African cassava mosaic virus infection” with an EOC:

Continue reading Journal flags paper over allegations it used competitors’ text, plasmids

Dental paper pulled for “wrong content with serious consequences”

Clinical Oral InvestigationsAn article on how missing teeth affect chewing was — well, pulled — when someone noticed a few errors. The journal later published a corrected version.

The retraction for “Chewing ability in an adult Chinese population” appeared in Clinical Oral Investigations in 2012, but we’re sharing it with you now because the notice contains some remarkable language:

This article has been withdrawn due to wrong content with serious consequences such as danger to people’s health.

Last author Nico H.J. Creugers, who works at Radboud University Medical Center in the Netherlands, told us: 

Continue reading Dental paper pulled for “wrong content with serious consequences”