50 years later, is it time to retract a retraction by a Nobel prize-winning author?

Georg Wittig
Georg Wittig

It’s not often that an article is retracted only to be later proven correct. But that may have happened this past summer in the chemistry literature.

In July, a group of researchers recapitulated an experiment largely similar to one that Nobelist Georg Wittig had performed – and subsequently retracted — decades earlier. Their findings suggest Wittig may actually have gotten it right the first time.

On July 27, Peter Chen of ETH Zurich and colleagues published an article online in the journal Angewandte Chemie International Edition that describes a new method for appending a carbon atom to an unsaturated hydrocarbon to create a three-membered ring – a useful chemical transformation known as cyclopropanation. Yet, it was not the first time researchers had reported such a process. As Chen and his colleagues note in the Israel Journal of Chemistry, Georg Wittig of the Ruprecht-Karls-Universität Heidelberg (who would go on to win the chemistry Nobel Prize in 1979) and Volker Franzen reported a similar reaction in 1960 in Angewandte Chemie, a German-language publication. Continue reading 50 years later, is it time to retract a retraction by a Nobel prize-winning author?

Mirror image in plant study flagged on PubPeer grows into retraction

djs_mpmi_28_9_cover-online.inddA 2010 paper on plant fungus has been retracted after a comment on PubPeer revealed that a study image had been flipped over and reused to represent two different treatments.

In May, a commenter pointed out the plants in Figure 2a of the paper in the journal Molecular Plant-Microbe Interactions “look remarkably similar.” A commenter writing under the name of corresponding author, Yukio Tosa at Kobe University in Japan, posted a response two days later agreeing with the assessment and stating that the paper should be retracted.

The notice reads: Continue reading Mirror image in plant study flagged on PubPeer grows into retraction

PLOS Genetics updates flagged paper with expression of concern

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PLOS Genetics has upgraded a notice on a paper to an expression of concern, raising the count for author chemist Ariel Fernandez to one retracted paper, and three expressions of concern.

The journal published “Protein Under-Wrapping Causes Dosage Sensitivity and Decreases Gene Duplicability” in 2008. In 2013, Fernandez corrected it, claiming that the work was not actually funded by the U.S. National Institutes of Health, as the original paper had said. The paper has been cited 33 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the expression of concern in full, which was published on September 14:

Continue reading PLOS Genetics updates flagged paper with expression of concern

Can you spot the signs of retraction? Just count the errors, says a new study

downloadClinical studies that eventually get retracted are originally published with significantly more errors than non-retracted trials from the same journal, according to a new study in BMJ.

The authors actually called the errors “discrepancies” — for example, mathematical mistakes such as incorrect percentages of patients in a subgroup, contradictory results, or statistical errors.

The study doesn’t predict which papers will eventually be retracted, since such discrepancies occur frequently (including one in the paper itself), but the authors suggest a preponderance could serve as an “early and accessible signal of unreliability.”

According to the authors, all based at Imperial College London, you see a lot more of these in papers that are eventually retracted: Continue reading Can you spot the signs of retraction? Just count the errors, says a new study

Here’s how to keep clinical trial participants honest (and why that’s a big deal)

NEJMAdditional lab tests, creating a clinical trial patient registry, and rewards for honesty are among the advice doled out in this week’s issue of the New England Journal of Medicine for researchers to help avoid the major issue of participants lying to get into clinical trials.

In the Perspective, David B. Resnik and David J. McCann, both based at the National Institutes of Health, address concerns raised by a 2013 survey of clinical trial participants that revealed “high rates” of “deceptive behavior.” Specifically: Continue reading Here’s how to keep clinical trial participants honest (and why that’s a big deal)

Investigation ups nursing researcher’s retraction count to 3

Journal of Clinical NursingThe Journal of Clinical Nursing is retracting a paper “due to major overlap with a previously published article” from the same journal, following an investigation by the National University of Singapore.

By our count, this is the third retraction for first author, Moon-fai Chan, all for “overlap” with other papers.

As we reported in May, the Journal of Advanced Nursing retracted a paper co-authored by Chan for “major overlap” with a paper in JCN, that too the result of the investigation. We’ve also learned that the journal Nursing & Health Sciences issued a similar notice last year for another pair of overlapped papers.

Chan said in a statement to Retraction Watch Continue reading Investigation ups nursing researcher’s retraction count to 3

Duke researcher with 7 retractions earns two Expressions of Concern

American Journal of Respiratory and Critical Care MedicineData issues continue to plague pulmonary papers co-authored by Duke University professor William Foster and former Duke researcher Erin Potts-Kant. Yesterday, the American Journal of Respiratory and Critical Care Medicine posted an Expression of Concern for two articles from the pair while the findings are “under review.”

The notice was published after the paper’s corresponding author, John Hollingsworth (also at Duke), told the journal that “some of the data published in these articles may be unreliable,” a term that we’ve gotten used to seeing from previous retractions.

Another Expression of Concern from the journal published earlier this year for another paper co-authored by Foster and Potts-Kant turned into a retraction months later. Hollingsworth was a co-author on that paper and another paper retracted from Environmental Health Perspectives in July.

Continue reading Duke researcher with 7 retractions earns two Expressions of Concern

Author appeals retraction after co-authors dispute Nature Comm paper

nature comm

Two weeks after Nature Communications published a paper on asymmetric cell division in July, it posted a retraction notice saying the paper was submitted “without the knowledge or consent” of all but the corresponding author.

The following day the journal “amended” the retraction note to include the initials of the corresponding author, Aicha Metchat, then based at European Molecular Biology Laboratory in Heidelberg, Germany.

The final notice for “An actin-dependent spindle position checkpoint ensures the asymmetric division in mouse oocytes” reads:

Continue reading Author appeals retraction after co-authors dispute Nature Comm paper

Journal corrects CrossFit injury data in paper at center of lawsuit

XLargeThumb.00124278-201509000-00000.CVA study on the trendy and grueling workout regimen known as CrossFit has a correction concerning the number of participants hurt during 10 weeks of training. The paper has been the center of multiple lawsuits  — one by CrossFit, and one by a CrossFit gym owner — for allegedly over-inflating the risks associated with the regimen.

The original paper claimed that 9 of 54 participants dropped out of the study due to “overuse or injury.” The correction note says that just two left for those reasons.

The paper, published in The Journal of Strength and Conditioning Research actually concludes that CrossFit has some benefits. According to the abstract: Continue reading Journal corrects CrossFit injury data in paper at center of lawsuit

When the title states the wrong result, a paper gets corrected

PLOS ONE

Ever wonder why, on a round-trip, the leg home often feels shorter? A group of researchers found that’s only true in hindsight, as people look back on which leg felt shorter — the trouble is, when the paper first appeared, the title mistakenly stated the opposite was true.

One June 10, PLOS ONE published a paper entitled “The Return Trip Is Felt Longer Only Postdictively: A Psychophysiological Study of the Return Trip Effect”; 17 days later, it was republished under the correct title, “The Return Trip Is Felt Shorter Only Postdictively: A Psychophysiological Study of the Return Trip Effect.”

On July 15, the journal posted a correction notice explaining its mistake:

Continue reading When the title states the wrong result, a paper gets corrected