Molecular mixup burns chemistry paper

advanced synthesis and catalysisChemists at Lanzhou University in China did the right thing last month, retracting a paper in Advanced Synthesis & Catalysis because of issues with a reactant that could only be corrected by changing “all the text and quantities.”

When the scientists were adding what was labeled Reactant 1 to the mix, they believed it was α-ethoxycarbonyl-α-azido-N-phenylacetamides. Unfortunately, what they were actually using was a decomposed version of the molecule, which threw everything off.

Here’s the notice for “tert-Butyl Hydroperoxide and Tetrabutylammonium Iodide- Promoted Free Radical Cyclization of α-Azido-N-arylamides”: Continue reading Molecular mixup burns chemistry paper

Study by deceased award-winning cancer researcher retracted because some patients were “invented”

cancerA 2002 paper has been retracted by Cancer after some of the authors notified the journal that they hadn’t agreed to submit it — and an investigation found that a number of the patients described had been made up.

Here’s the notice for “Radioimmunotherapy of small-volume disease of metastatic colorectal cancer: results of a phase II trial with the iodine-131–labeled humanized anti–carcinoembryonic antigen antibody hMN-14:” Continue reading Study by deceased award-winning cancer researcher retracted because some patients were “invented”

Stats error has chilling effect on global warming paper

global change biologyIt turns out a 2014 paper that found a surprising pattern of plant migration in response to global warming was not so surprising after all — it’s been retracted by the authors due to a mistake in the statistical analysis.

Most studies on migrating populations have found that species around the globe move north to escape the rising temperatures. But the authors of the 2014 paper in Global Change Biology found the opposite — according to their analysis, many plant species in Western North America had been migrating south, toward warmer climates.

The lead author Melanie Harsch told Science in 2014 that the team had been suspicious of the analysis, and so ran it twice: Continue reading Stats error has chilling effect on global warming paper

Sticky situation: Paper using honey for healing pulled over data issues

honey
Image via Hillary Stein

A paper on dressing wounds with honey has been retracted after the journal realized that an outlier patient was throwing off the data analysis.

Honey has been used for millennia as an antimicrobial wound dressing. Doctors can even buy sterile preparations of the sweetener. But the evidence that honey is better than other wound dressings is still inconclusive.

According to the retracted paper, published in International Wound Journal in 2008, Manuka honey has an acidic pH which helps reduce the alkaline environment of chronic woulds. Indeed, the authors found that Manuka honey dressings lowered wound pH and reduced wound size.

Sadly, the paper was pulled in 2014, after someone realized one patient had a particularly large wound that was throwing off statistics. The injury was 61 cm^2 at the beginning of the study, while the others ranged from .9 to 22 cm^2. After removing that patient from the analysis, the results no longer held up.

Continue reading Sticky situation: Paper using honey for healing pulled over data issues

Chemists Bielawski and Wiggins up to eight expressions of concern, one retraction

bielawski
Christopher Bielawski

Two researchers who already had three expressions of concern under their belts have five more, plus a retraction.

Kelly Wiggins and Christopher Bielawski share authorship on all the papers in question. After the first set of EoCs, Bielawski, at the time a PI at UT Austin, told Chemistry and Engineering News that a “former lab member” had admitted to faking the data. The recent retraction indicates that University of Texas at Austin’s Office of Research Integrity formally investigated the lab, and determined that Bielawski was telling the truth about a former lab member being to blame.

Bielawski has since taken a post at Ulsan National Institute of Science and Technology in South Korea. He told us that move was unrelated to anything that happened at UT Austin, but declined to answer other questions. Wiggins got a postdoc at the University of Illinois, which an Illinois spokesperson confirmed lasted from July 1 2013 to January 22 2014; we’re waiting to hear back on our question about whether her departure had anything to do with misconduct.

Here’s the retraction notice for “A Mechanochemical Approach to Deracemization,” in Wiley journal Angewandte Chemie: Continue reading Chemists Bielawski and Wiggins up to eight expressions of concern, one retraction

Italian researcher facing criminal charges notches seventh retraction

proteomicsAlfredo Fusco, a researcher in Italy under criminal investigation, now has a seventh retraction for manipulated images.

Here’s the notice for “Retraction: Identification of new high mobility group A1 associated proteins,” to which not all of the authors agreed: Continue reading Italian researcher facing criminal charges notches seventh retraction

Overly honest references: “Should we cite the crappy Gabor paper here?”

ethologyWe never cease to be amazed what can make it through peer review and several levels of editing.

In this case, some fish mating researchers wrote an, um, love note to their peers that failed to be edited out by any of the many eyes who must have at least glanced over it.

Here’s our favorite passage in “Variation in Melanism and Female Preference in Proximate but Ecologically Distinct Environments” (emphasis ours), published in Ethology:

Continue reading Overly honest references: “Should we cite the crappy Gabor paper here?”

It’s happened again: Journal “cannot rule out” possibility author did his own peer review

ijkcThomson Reuters’ online peer review system ScholarOne is having quite a year.

This summer, a scientist exploited basic security flaws in how the system accepts author suggestions for peer reviewers to review a whole pile of his own manuscripts, ultimately resulting in the retraction of 60 papers and the resignation of the Taiwan minister of education.

Now, another journal that uses the system, Wiley’s International Journal of Chemical Kinetics, has retracted a paper because the authors provided their own peer reviewers and “the identity of the peer reviewers could subsequently not be verified.”

We asked editor Craig A. Taatjes if he was concerned the authors had conducted their own peer review. His response is reflective of many of the breaches we’ve seen so far for these online systems: Continue reading It’s happened again: Journal “cannot rule out” possibility author did his own peer review

Chemical engineering journal retracts paper with unknowing author

AiChemE-logoAIChemE’s website promises, “Subscribing to the AIChE Journal is like having access to nine topical journals in the field.”

Without a subscription, though, you might miss out on some valuable topical information – like why a paper you want to cite has been retracted, something the Committee on Publication Ethics recommends be freely available.

Here’s the notice for “Flow Structure and Particle Motions in a Gas-Polyethylene Fluidized Bed,” originally published in 2007:

Continue reading Chemical engineering journal retracts paper with unknowing author

Tonic-clonic stats error sinks epilepsy paper

pm_cover_dez_01A brain imaging study in children with epilepsy has been retracted by the Journal of Magnetic Resonance Imaging due to a statistics error.

Here’s the notice for “Microstructural Brain Abnormalities of Children of Idiopathic Generalized Epilepsy With Generalized Tonic-Clonic Seizure: A Voxel-Based Diffusional Kurtosis Imaging Study”: Continue reading Tonic-clonic stats error sinks epilepsy paper