In 2012, John Carlisle, a British anesthesiologist, demonstrated conclusively using statistics that Yoshitaka Fujii had faked data in many studies. Fujii — as followers of this blog well know — now holds the record for most retractions by an individual author (183).
Carlisle’s work accomplished two things: It put to rest any doubt that problems with Fujii’s work might have resulted from innocent mistakes, and it gave journals a mathematical tool for conducting investigations into potential cases of misconduct.
Now comes the payoff. In a new paper, Carlisle and another anesthesiologist, John Loadsman, take aim at one of Fujii’s frequent co-authors, Yuhji Saitoh of Yachiyo Medical Center and Tokyo Women’s Medical University in Japan. The pair analyzed data from 31 studies Saitoh published between 1993 and 2012 — including one study that was rejected in 2015 — for a total of 32 papers. Of those, 23 did not include Fujii as an author.
As we’ve written previously, John Carlisle, an anesthesiologist in the United Kingdom, analyzed nearly 170 papers by Fujii and found aspects of the reported data to be astronomically improbable. It turns out, however, that he made a mistake that, while not fatal to his initial conclusions, required fixing in a follow-up paper, titled “Calculating the probability of random sampling for continuous variables in submitted or published randomised controlled trials,” also published in Anaesthesia.
Xenon may be an inert gas, but that doesn’t mean papers about the molecule aren’t subject to change.
Indeed, the journal Anaesthesia has retracted a 2010 article about xenon-based anesthesia, and corrected a 2005 article by some of the same researchers, for what appears to be a case of wurst slicing.
The 2005 paper, “Comparison of xenon-based anaesthesia compared with total intravenous anaesthesia in high risk surgical patients,” came from a group at the Department of Anaesthesiology and Intensive Care Medicine at University Hospital Schleswig-Holstein, in Kiel, Germany. It has been cited 10 times, according to Thomson Scientific’s Web of Knowledge.
Unglaublich is the German word for unbelievable, and it’s an apt description for the latest development in the case of Joachim Boldt.
Boldt, a prominent German anesthesiologist, has been at the center of a research and publishing investigation since last October, when the journal Anesthesia & Analgesiaretracted a 2009 article of his over concerns of data manipulation. This morning, the German medical board overseeing the case, the Landesärztekammer Rheinland-Pfalz (LÄK-RLP), released its findings — and they are truly stunning.
According to LAK, somewhere in the neighborhood of 90 of Boldt’s published articles might require retraction because the investigator failed to obtain approval from an institutional review board to conduct the research.