Category: by journal

Widely publicized Nature study on human age limit draws fire

Statisticians are mounting a challenge to a much-publicized study suggesting that human lifespan has a limit of approximately 115 years — 125, tops.

Published last October in Nature, the study from scientists at Albert Einstein College of Medicine in New York was the eleventh most talked-about piece of research in 2016, according to Altmetric. The paper is not yet indexed in Clarivate Analytics’ Web of Science.

But now, multiple research teams have described what they see as flaws in either the statistical methods or underlying reasoning of the study. Today, Nature published five peer-reviewed rebuttals, in response to the study. Another scientist described his concerns about the paper in April in F1000 Research.

The five papers in Nature are published as Brief Communications Arising, the journal’s way of flagging an important debate over a paper. The short papers provide new data to challenge a central part of a paper’s conclusions. The study’s authors, however, have responded to all five, defending their methods, especially their controversial decision to rely in part upon a visual inspection of mortality data in concluding there is a limit to human lifespan. Senior author Jan Vijg, a geneticist, told Retraction Watch:

Continue reading Widely publicized Nature study on human age limit draws fire

Plagiarism costs author five papers in five different journals

An engineering researcher has written about models tackling a range of complex issues — security problems in Iraq, poverty in Europe, and emergency responses to humanitarian crises. But there may be some limits to his expertise: Between 2016 and 2017, five journals have retracted five of his papers, citing plagiarism.

Some of the notices describe the plagiarism as “extensive,” “significant,” and “substantial.” One journal editor, who retracted one of Kubilay Kaptan’s papers last year, told us the paper “was simply a direct copy from an existing one.”

The editor noted that Kaptan — who lists his affiliation as the Civil Engineering Department at Beykent University in Istanbul — claimed to be “the victim of a personal smear campaign, which involved submitting plagiarised manuscripts in his name.” We reached out to Kaptan several times by phone and email to verify this claim, but did not hear back.

Here’s the most recent retraction, for a 2016 paper published in Journal of Refugee Studies:   Continue reading Plagiarism costs author five papers in five different journals

Cancer paper retracted after author discovers signs of data manipulation

A molecular biology journal has retracted a 2017 cancer paper only two months after it appeared online, after the corresponding author notified the journal about possible data manipulation.

According to the notice, Chunsun Fan, from Qidong Liver Cancer Institute & Qidong People’s Hospital in China, requested the retraction after finding “signs of data manipulation” in the paper that was published online in April. The journal, FEBS Letters, acted quickly, publishing a retraction earlier this month.

Here’s the retraction notice for “MiR-19 regulates breast cancer cell aggressiveness by targeting profilin 1:” Continue reading Cancer paper retracted after author discovers signs of data manipulation

“Searching our souls”: Authors retract paper after researcher admits to fabricating data

Researchers at a prominent Japanese university have retracted a 2016 paper in a chemistry journal after the first author admitted to scientific misconduct.

According to the notice, Kyushu University investigated and verified that the first author had committed scientific misconduct.

We requested a copy of the misconduct report, which revealed that the researcher, Prasenjit Mahato, a postdoctoral fellow at Kyushu University who is no longer affiliated with the university, “admitted to falsifying research” in two papers on which he was first author: a highly cited 2015 paper in Nature Materials, which was retracted in 2016, as well as the 2016 paper in Journal of the American Chemical Society (JACS), retracted earlier this month. The university investigated and confirmed misconduct in both papers.

We covered the Nature Materials retraction last year, but at the time, the paper’s corresponding author, Nobuo Kimizuka, only told us that the “matter has been under investigation by the formal investigation panel of our University.”

According to the five-page misconduct report — which we translated from Japanese using One Hour Translation and is also available in Japanese on the university’s website — in July 2016, a member of the lab (“Faculty Member B”) began to suspect a problem after he reviewed the data with Mahato (“the defendant”): Continue reading “Searching our souls”: Authors retract paper after researcher admits to fabricating data

Instead of retracting a flawed study, a journal let authors re-do it. It got retracted anyway.

When a journal discovers elementary design flaws in a paper, what should it do? Should it retract immediately, or are there times when it makes sense to give the researchers time to perform a “do-over?”

These are questions the editors at Scientific Reports recently faced with a somewhat controversial 2016 paper, which reported that microRNAs from broccoli could make their way into the nuclei of human cells — suggesting that the food we eat could affect our gene expression.

After the paper appeared, researcher Kenneth Witwer at Johns Hopkins — who was not a co-author — posted comments on PubMed Commons and the paper itself, noting that the authors hadn’t properly designed the experiment, making it impossible for them to detect broccoli microRNAs. 

But instead of retracting the paper, the journal decided to give the authors time to do the experiments again, this time with correctly designed molecular biology tools. When that failed, they retracted it — and as part of the notice, reported the exact opposite conclusion of the original.

Witwer said the authors did a “tremendous job” with the follow-up study, but he still thinks the journal should have retracted the paper immediately. Letting the authors redo it is “a dangerous precedent to set,” he told us:   

Continue reading Instead of retracting a flawed study, a journal let authors re-do it. It got retracted anyway.

Journal retracts two papers by authors who lifted others’ data

A journal has retracted two 2014 papers after the editors discovered the authors used data from other research groups without permission.

The papers, both published in the same issue of Cell Biochemistry and Biophysics and retracted in May, suffered from similar issues—the authors published data that was not theirs. The authors are all based at different institutions in China; as far as we can tell, the papers do not have any authors in common.

When we asked the publisher whether a third party, such as a paper mill, may have been involved, a spokesperson for Springer told us: Continue reading Journal retracts two papers by authors who lifted others’ data

No new math: Journal pulls math paper with “already known” results

A mathematics journal has withdrawn a paper after discovering that the results were not new.

The paper, published online in March in Communications in Algebra, explored the properties of group rings, a discipline of algebra. According to editor-in-chief of the journal, Jason Bell, author Francis E. A. Johnson, a professor of mathematics at the University College London, devised a property associated with group rings, and defined it using the term “weakly finite.” But, at the time, Johnson was not aware that other experts had already defined the same property, using the term “stably finite.”

Bell, a professor of mathematics at the University of Waterloo in Ontario, and Lance Small, the journal’s other editor-in-chief, stressed that this issue was “definitely not a matter of plagiarism.” Bell and Small told us in a joint statement that “it was ultimately no one’s fault—it is just one of these things that can happen occasionally in mathematics research.” But given the overlap, the editors thought it best to withdraw the paper, they said: Continue reading No new math: Journal pulls math paper with “already known” results

12 years after researcher found guilty of misconduct, journal retracts paper

In 2005, the U.S. Office of Research Integrity found an obesity researcher had engaged in scientific misconduct.

More specifically, the ORI report revealed that Eric Poehlman, then based at the University of Vermont, had “falsified and fabricated” data in 10 papers. The 2005 report asked that the journals issue retractions or corrections to the papers. By 2006, six of those papers were retracted (1, 2, 3, 4, 5, 6). In 2006, a judge sentenced Poehlman to one year and one day in prison for falsifying research data.

In 2015, we explored how long it takes a journal to retract a paper. We found that four of the 10 papers had still not been retracted — one appeared to be missing from Medline, another had received a correction (as the ORI report requested), and two had not been retracted or corrected (1, 2).

Until now. Continue reading 12 years after researcher found guilty of misconduct, journal retracts paper

Journal alerts readers to “technical criticism” of CRISPR study

A Nature journal has posted a editor’s note to a recent letter on potential unintended consequences of CRISPR gene editing, after an executive at a company trying to commercialize the technology said the paper should be retracted.

The original article, published on May 30 as a correspondence in Nature Methods, suggested that using CRISPR in mice can lead to unexpected mutations. But last week, the journal added an “Editorial note” online. Nature Methods says the notice is not an expression of concern, which would be a stronger suggestion that the paper is problematic; it simply wants to alert readers to the fact that, as the note states:

Continue reading Journal alerts readers to “technical criticism” of CRISPR study

Big corrections usually weaken findings. But a recent NEJM one strengthened them, author says

A 2016 study in New England Journal of Medicine has received a substantial correction, which affected several aspects of the article.

Typically, an error that affects so much of a paper would undermine the results (and possibly lead to a retraction). But in this case, the revised dose calculations actually strengthened the findings, according to the first author.

The NEJM study aimed to clarify whether patients with a neuromuscular disease called myasthenia gravis benefit from a surgical procedure to remove the thymus. About half of the patients received surgery plus the steroid prednisone, while the rest only received the steroid. The researchers found patients who received the surgery fared better.

Shortly after the paper was published in August 2016, the authors discovered an error in the calculation of the average prednisone dose. According to Gil Wolfe, the first author of the paper, when the researchers corrected the error: Continue reading Big corrections usually weaken findings. But a recent NEJM one strengthened them, author says