“I hold my hands up”: PubPeer criticisms spark a biochemist’s offer to retract

MPIn a back-and-forth on PubPeer, a researcher appears to have offered to retract a paper after commenters challenged the use of identical control bands on a gel.

A person writing as Virginia Commonwealth University biochemist Paul Dent admitted the control bands of his 2007 Molecular Pharmacology paper, “Human Chorionic Gonadotropin Modulates Prostate Cancer Cell Survival after Irradiation or HMG CoA Reductase Inhibitor Treatment,” were duplicated “for comparison purposes,” but stated he was “in no way attempting to ‘intentionally manipulate the data.’”

In response, Dent appeared to offer to pull the paper, about using a hormone to help kill prostate cancer cells:

Continue reading “I hold my hands up”: PubPeer criticisms spark a biochemist’s offer to retract

Exosome pioneer’s paper retracted after investigation finds “multiple” faked figures

JImmunolThe Journal of Immunology is retracting a 2006 article about the role of exosomes in pregnancy at the behest of the University of Louisville in Kentucky, following a misconduct investigation that “determined multiple figures” in the paper were falsified.

First author Douglas Taylor is a pioneer in exosome biology, having discovered the release of exosomes from tumor cells in the 1970s.

The retracted paper identified “significant quantitative and qualitative differences in released exosomes” in the placentas of fetuses delivered prematurely compared to those delivered without complications at term, particularly relating to immune regulation.  It has been cited 150 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction note (which is paywalled – tsk, tsk): Continue reading Exosome pioneer’s paper retracted after investigation finds “multiple” faked figures

Another “first author has accepted responsibility” retraction from immunity journal

IAIScientists have pulled their 2013 Infection and Immunity paper after a reader noticed duplicated data in three figures, and the first author was “unable to provide the original data used to construct the figures,” according to the journal’s editor-in-chief.

According to the retraction note, “the first author has accepted responsibility for these anomalies” — similar to another recent retraction from the same journal, also due to image duplication reported by a reader (apparently the journal has one or more careful readers).

The paper, “Pseudomonas aeruginosa Outer Membrane Vesicles Modulate Host Immune Responses by Targeting the Toll-Like Receptor 4 Signaling Pathway,” concerns the role of outer membrane vesicles excreted by the bacteria to incite an inflammatory response in mice. It was written by authors at the University of North Dakota, Sichuan University in China, and the University of Chicago, and has been cited six times, according to Thomson Scientific’s Web of Knowledge.

Here’s the complete retraction note:

Continue reading Another “first author has accepted responsibility” retraction from immunity journal

“A decision of misconduct was reached”: Two lung papers expire

JofAnesthTwo papers about the molecular underpinnings of lung damage are being retracted following an investigation at Oita University in Japan, which revealed that images from both papers had been used to depict “different experimental conditions” in a third paper (which has not been retracted).

It’s not clear which of the authors were the subject of the investigation. The two retracted papers, “Nafamostat mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury” in the Journal of Anesthesia and “Coexpression of HSP47 Gene and Type I and Type III Collagen Genes in LPS-Induced Pulmonary Fibrosis in Rats” in Lung, both originally published in 2007, share the same first author — Satoshi Hagiwara, whose affiliation is listed as the Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine. The papers have been cited 13 times and 12 times, respectively, according to Thomson Scientific’s Web of Knowledge. Hagiwara is also the first author on the third paper that contains the duplicated images.

The first retraction notice reads:

Continue reading “A decision of misconduct was reached”: Two lung papers expire

More “unsubstantiated conclusions” partially sink another origin of life paper

OrigLife_ak17A trio of researchers based in Russia is asking to pull another set of figures and a table from a 2008 paper on modeling ATP formation after an investigation found the fourth researcher – the first author on the paper — “falsified or fabricated” the data they reflect.

The paper, in Origins of Life and Evolution of Biospheres, is the second partial retraction from many of the same authors for the same reason. Both journals also issued erratum notices, which read quite similarly. Here’s the latest note:

Continue reading More “unsubstantiated conclusions” partially sink another origin of life paper

Article on suicide in Egypt retracted for double publication

JForensicSci_ak9A 2012 article published in the Journal of Forensic Sciences is being retracted because of an “overlap with a previous publication by the same authors.”

The corresponding author, Heba Yassa, a lecturer at Assiut University in Egypt, readily explained in an email exchange that the mix-up was due to a miscommunication with the editor of another journal, which she believed was not going to publish the article. “I know accidentally that the editor…published the article.”

The article, which examined suicides in one of the largest provinces in Egypt between 2005 and 2009, found rates had gone up since 1987, and men tended to use more violent methods than women.

Here’s the retraction notice: Continue reading Article on suicide in Egypt retracted for double publication

We’ll tell you later, says ophthalmology journal about retracted paper

EurOpthRevThe European Ophthalmic Review has retracted a 2014 article about the macular degeneration drug aflibercept without any explanation.

Here’s the retraction notice, such as it is:

Continue reading We’ll tell you later, says ophthalmology journal about retracted paper

“Will you marry me?”: An unusual note sneaks into acknowledgements of scientific paper

This is an artistic life reconstruction of the new horned dinosaur Regaliceratops peterhewsi in the palaeoenvironment of the Late Cretaceous of Alberta, Canada. SOURCE: Art by Julius T. Csotonyi. Courtesy of Royal Tyrrell Museum, Drumheller, Alberta.
Artist’s rendering of Regaliceratops peterhewsi, by Julius T. Csotonyi, courtesy of Royal Tyrrell Museum

Scientists have discovered the skull of a new dinosaur, a feathered relative of the Triceratops, according to new findings released in Current Biology today.

Now, we know what you may be thinking – we don’t normally cover science news. We’re writing about this paper because of a little note we saw in the acknowledgements:

Continue reading “Will you marry me?”: An unusual note sneaks into acknowledgements of scientific paper

Cell Press investigating possible image manipulation in influential yeast genetics paper

cellCell Press is looking into anonymous allegations that a pair of influential papers on gene activation in yeast may contain more than two dozen instances of image manipulation, according to a spokesperson for the journal.

The accusations first appeared in March on PubPeer, where they triggered a small avalanche of comments, including one asserting “unambiguous and repeated examples of data re-use.”

The concerns raised on PubPeer have even sparked an investigation by an institution in Spain, which found no evidence to support the allegations. But not everyone agrees with that verdict.

Continue reading Cell Press investigating possible image manipulation in influential yeast genetics paper

Flood paper washed away after “oversight” leads to publication of wrong manuscript

JEHSEThe editor of the Journal of Environmental Health Science and Engineering has retracted a paper mapping flood zones in Iran because the authors mistakenly uploaded a manuscript that had already been published elsewhere.

According to corresponding author Majid Bagheri of K.N. Toosi University of Technology in Tehran, a different paper on wastewater treatment was accepted and peer-reviewed at JEHSE, but then the authors uploaded the wrong manuscript, and that manuscript, on flood zones, made it all the way through acceptance and publication due to an “oversight.”

The retracted version of the paper was published online on December 27, 2014 in JEHSE, a BioMed Central title. The preceding, non-retracted version, was published online at the Arabian Journal for Science and Engineering just four days earlier, on December 23, 2014.

Here is Bagheri’s account: Continue reading Flood paper washed away after “oversight” leads to publication of wrong manuscript