Category: blood (journal) retractions

Blood pulls deceased star oncologist’s paper after Stanford inquiry

Blood has retracted a 2011 article by a now-deceased Stanford researcher, Holbrook Kohrt,  who earlier this month lost two other papers over concerns about the whereabouts of the data. 

The journal’s move comes about a week after Retraction Watch posted a story on the previous retractions, in the Journal of Clinical Investigation (JCI), of Kohrt’s work. As we noted then, Kohrt was a superstar young faculty member who died in 2016 of complications of hemophilia. He was the subject of this 2013 profile in the New York Times, which also wrote an obituary of him. 

The Blood paper was titled “CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies.” The paper has been cited 148 times, according to Clarivate Analytics’ Web of Science.

Continue reading Blood pulls deceased star oncologist’s paper after Stanford inquiry

Sickle cell screening abstract retracted for host of reasons, including an ambivalent co-author

A scanning electron microscope image of a sickle cell, digitally colorized (via US CDC)

Researchers have lost a 2018 conference abstract on screening for sickle cell disease in Africa over a dispute over authorship and the lack of appropriate disclosures.  

The article, “Implementation of a sickle cell disease screening initiative in Uganda with HemoTypeSC(TM),” which was presented at a 2018 conference and then appeared in Blood, described a much-touted new blood test for sickle cell trait from a company in California called Silver Lake Research.

But according to the retraction notice, a noted public health researcher in Uganda said his name had appeared on the abstract without his permission: Continue reading Sickle cell screening abstract retracted for host of reasons, including an ambivalent co-author

Cancer researcher contributed “false data” to 11 studies

ori-logoA former cancer researcher has falsified data in 11 studies, according to the results of a investigation scheduled to be published in the Federal Register tomorrow.

The Office of Research Integrity’s findings are based on an inquiry at Virginia Commonwealth University, where Girija Dasmahapatra worked until July of this year, investigating possible therapies for cancer. The misconduct affected research funded by three grants from the National Institutes of Health. Steven Grant, a researcher at VCU, is the principal investigator on the grants, each of which total over $2 million in funding. All of the 11 affected papers will be corrected or retracted, according to the ORI notice.

Two of the papers containing “falsified and/or fabricated” data — a study on an experimental combination of drugs for blood cancer and one on chemotherapies for rare forms of lymphoma  — were covered in press releases by VCU.

According to the notice in the Federal Register:

Continue reading Cancer researcher contributed “false data” to 11 studies

Correction “does not change the scientific meaning” of leukemia letter

blood

The journal Blood has issued a correction in a 2009 letter about the molecular underpinnings of chronic lymphocytic leukemia.

Despite the extent of the changes to a figure, “the error does not change the scientific meaning,” according to the erratum.

The article “p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia” was written in response to a 2009 Blood paper about the role of a microRNA in CLL. But its western blots were “assembled incorrectly,” leading to duplicated panels. Another set of panels was “shifted.”

So the authors repeated the experiments, and presented them in a correction. Here’s the correction notice in full, published earlier this month, including the figures in question:

Continue reading Correction “does not change the scientific meaning” of leukemia letter

Stem cell researcher Jacob Hanna’s correction count updated to 10

Jacob Hanna
Jacob Hanna

Thanks to some eagle-eyed readers, we’ve been alerted to some corrections for high profile stem cell scientist Jacob Hanna that we had missed, bringing our count to one retraction and 13 errata on 10 papers.

The problems in the work range from duplications of images, to inadvertent deletions in figures, to failures by his co-authors to disclose funding sources or conflicts of interest. Hanna is the first or last author on 4 of the papers, and one of several on the rest.

First up, a correction to a Cell paper on which Hanna is the first author:

Continue reading Stem cell researcher Jacob Hanna’s correction count updated to 10

Cell biologist Hanna issues two errata; images mysteriously disappear from Imgur

Jacob Hanna
Jacob Hanna

Cell biologist Jacob Hanna, the highly cited stem cell researcher currently at the Weizmann Institute of Science,  has posted a long erratum for a 2005 paper in Blood for “inadvertent mistakes,” among other issues; soon after, Hanna’s team issued another erratum for a 2009 Cell Stem Cell paper.

There’s more to tell: Last month, commenters on PubPeer noticed that images from at least 10 of the research papers Hanna coauthored in seven journals — that commenters had posted on the image hosting website Imgur and linked to on PubPeer — had been deleted.

Imgur did not confirm whether these specific images had been deleted, but told Retraction Watch:

Continue reading Cell biologist Hanna issues two errata; images mysteriously disappear from Imgur

Stem cell researcher Hanna “working…to correct the unfortunate and inadvertent mistakes” in papers

jacob
Jacob Hanna

Jacob Hanna of Israel’s Weizmann Institute has been a media darling for years, including as a member of the 2010 Technology Review 30 under 35 for his work with stem cells.

However, questions have been mounting about his research, both on PubPeer (which has critical comments for 15 papers he’s an author on) and in other stem cell labs, who have not been able to reproduce much of Hanna’s work.

We asked Hanna about a PubPeer entry specific to a 2005 paper in Blood. Commenters have accused the authors of figure manipulation and possible data republication. Here’s a figure from that post: Continue reading Stem cell researcher Hanna “working…to correct the unfortunate and inadvertent mistakes” in papers

A year after ORI report, hematology journal retracts faked paper

bloodA year after an ORI report discredited the work of former University of Washington in Seattle researcher Andrew Aprikyan, one of the papers named in the report has finally been retracted.

Here’s the notice for “Impaired survival of bone marrow hematopoietic progenitor cells in cyclic neutropenia”:  Continue reading A year after ORI report, hematology journal retracts faked paper

Journal retracts stem cell study despite objections of most authors

Gerold Feuer in 2008, via Upstate
Gerold Feuer in 2008, via Upstate

The journal Blood has retracted a 2010 paper over the objections of most of its authors, two of whom were found by their university to have used “fraudulent methods” to obtain the data.

We first reported on the case of Gerold Feuer last fall. The State University of New York (SUNY) Upstate Medical Center in Syracuse fired Feuer in 2010 after determining that he had misused state funds to enrich a company he had founded, HuMurine. A court agreed with many of the university’s claims, but ordered his reinstatement in 2012.

Meanwhile, as we noted last fall: Continue reading Journal retracts stem cell study despite objections of most authors

Contaminated cells force retraction of Blood paper

blood414Blood has an interesting retraction of a 2011 paper on what a group of authors claimed was a new cell line — but which proved, apparently, to be a chimera.

The article, “Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC,” came from a team at Universität Duisburg-Essen, in Germany, and has been cited 21 times, according to Thomson Scientific’s Web of Knowledge. Here’s the abstract: Continue reading Contaminated cells force retraction of Blood paper