PLOS ONE retracts breast cancer genetics paper after claim of misappropriated data

plosonePLOS ONE has retracted a 2012 article by a group of breast cancer researchers after another scientist — a leading U.S. oncologist — objected that the data came from his lab.

The paper, “GREB1 Functions as a Growth Promoter and Is Modulated by IL6/STAT3 in Breast Cancer,” came from a team composed of researchers at the Morehouse School of Medicine, Xavier University of Louisiana and the University of Miami School of Medicine. It purported to find that: Continue reading PLOS ONE retracts breast cancer genetics paper after claim of misappropriated data

Dipping into history: An 87-year-old retraction in a statistics journal

jamstatsocWe came across a rather long-toothed retraction in the Journal of the American Statistical Association, which represents a case of doing the right thing (similar to that involving the apparent first-ever English language retraction from 1756, about which we wrote in 2012).

The 1927 notice came in the form of a letter by C. H. Whelden Jr., who was for a time the chief statistician for the American National Red Cross, referencing his 1926 article in the JASA,”The Trend-Seasonal Normal in Time Series:”

Continue reading Dipping into history: An 87-year-old retraction in a statistics journal

CrossFit to be tied: Fitness company sues journal to retract “sloppy and scientifically unreliable work”

Lawsuits are usually dry and boring, so it’s always fun to read one with a little life.

Here’s one of those: CrossFit, the fitness program famous for its brief, strenuous exercises and passionate devotees, is suing the National Strength and Conditioning Association (NCSA), which it considers its staid competitor for the nation’s sweat and cash.

According to CrossFit, the NSCA published a study with a “falsified rate of injury,” “in an effort to portray CrossFit as ‘dangerous’ and therefore a fitness program that should be avoided.”

No matter that the study, published in NSCA’s official research journal, the Journal of Strength and Conditioning Researchconcluded overall that CrossFit is a useful form of exercise. The suit says that the authors fudged a few statistics about participants’ injuries. Here’s the relevant section from the paper, titled “Crossfit-based high-intensity power training improves maximal aerobic fitness and body composition:”

Continue reading CrossFit to be tied: Fitness company sues journal to retract “sloppy and scientifically unreliable work”

Mystery box sinks immunology paper

Screen Shot 2014-06-30 at 12.30.32 PMBiochemical Journal has pulled a 2006 paper for an undisclosed “background subtraction box” in an image – which, if you take a not-particularly-close look at the figure to the right, means somebody added a black rectangle over the control lane.

Here’s the notice: for “Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4a transcriptional activity”: Continue reading Mystery box sinks immunology paper

University where researcher faked HIV vaccine findings won’t receive last $1.4 million of grant

iowa stateThere has been another development in the case of Dong-Pyou Han, the former Iowa State University (ISU) researcher who admitted last fall to spiking rabbit blood samples to make it look as though his team’s HIV vaccine was working in the animals.

The Des Moines Register reports: Continue reading University where researcher faked HIV vaccine findings won’t receive last $1.4 million of grant

Rapid mood swing: PNAS issues Expression of Concern for controversial Facebook study

pnas 1113The Proceedings of the National Academy of Sciences (PNAS) is subjecting a much-criticized study involving Facebook that it published just two weeks ago to an Expression of Concern.

From the abstract of the original study: Continue reading Rapid mood swing: PNAS issues Expression of Concern for controversial Facebook study

Faked figure sinks paper on potential new MRI contrast agent

langd5_v030i025.inddSurface chemistry journal Langmuir has retracted an article on a new MRI contrast agent — but only one of the authors agreed.

According to the notice:

Continue reading Faked figure sinks paper on potential new MRI contrast agent

STAP stem cell papers officially retracted as Nature argues peer review couldn’t have detected fatal problems

nature 714A significant chapter of the nearly six-month saga of the STAP stem cell controversy has come to an end, with Nature running retraction notices for the two papers involved. The journal has also published an editorial about the case that’s worth a read.

The retractions for “Bidirectional developmental potential in reprogrammed cells with acquired pluripotency” and “Stimulus-triggered fate conversion of somatic cells into pluripotency” both read: Continue reading STAP stem cell papers officially retracted as Nature argues peer review couldn’t have detected fatal problems

Chemistry paper in Science earns expression of concern for unreliable data

science 62714A 2011 paper in Science has been subjected to an expression of concern and has led to an investigation by the Texas university where the work was done.

Here’s the expression of concern, signed by Science editor in chief Marcia McNutt (and paywalled): Continue reading Chemistry paper in Science earns expression of concern for unreliable data

Alleged Medicare cheat loses paper for data mix-up

A Boston doctor indicted on charges of Medicare fraud in 2007 has had a paper relating to the case retracted this month.

Abdul Razzaque Ahmed was considered something of a miracle worker by his patients, treating two rare and disfiguring skin conditions called pemphigoid and pemphigus vulgaris. He used more powerful medicines than the typical course of treatment, including a drug normally used to treat cancer.

The initial indictment stated that Ahmed mixed blood samples to falsely show a “dual diagnosis” of both diseases, and prove to Medicare that they required the more rigorous (and expensive) treatment. It also alleged that he profited massively from the government pay-outs. He was convicted of obstruction in 2007; the other charges were dropped when he agreed to forfeit assets worth $2.9 million.

Now, a 2001 paper by Ahmed, which claimed fifteen patients had a dual diagnosis, has been retracted because the samples were all mixed. Here is the retraction notice from Clinical Immunology: Continue reading Alleged Medicare cheat loses paper for data mix-up