Science retracts paper after Nobel laureate’s lab can’t replicate results

Science is retracting a 2014 paper from the lab of a Nobel winner after replication attempts failed to conclusively support the original results.

In January, Bruce Beutler, an immunologist at University of Texas Southwestern Medical Center and winner of the 2011 Nobel Prize in Physiology or Medicine, emailed Science editor-in-chief Jeremy Berg to report that attempts to replicate the findings in “MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses” had weakened his confidence in original results. The paper had found that virus-like elements in the human genome play an important role in the immune system’s response to pathogens.

Although Beutler and several co-authors requested retraction right off the bat, the journal discovered that two co-authors disagreed, which Berg told us drew out the retraction process. In an attempt to resolve the situation, the journal waited for Beutler’s lab to perform another replication attempt. Those findings were inconclusive and the dissenting authors continued to push back against retraction.

Berg told us:

Continue reading Science retracts paper after Nobel laureate’s lab can’t replicate results

“My dog ate the data:” Eight excuses journal editors hear

As a journal editor, are you tired of hearing the same excuses from authors who are facing allegations of problematic data? If so, you’re not alone.

Recently, an editor of the journal Oncogene co-authored an editorial in the journal listing the types of excuses he often hears — and why none of them is valid. Writing the article with editor Justin Stebbing of Imperial College/Imperial Healthcare NHS Trust is David Sanders of Purdue University. Sanders himself has raised allegations of misconduct against a cancer researcher (and is currently being sued for defamation as a result).

Here are the problematic excuses they encounter:

Continue reading “My dog ate the data:” Eight excuses journal editors hear

Florida researcher “cherry picked” data, university investigation finds

Credit: University of Florida

A journal has retracted a 2014 paper after a university investigation found that the first author only reported certain data points that supported the paper’s conclusion.

Based on a whistleblower’s tip, the University of Florida investigated work by Huabei Jiang, a professor of biomedical engineering, and Lei Yao, a former postdoc and scientist in Jiang’s lab, for research misconduct. According to documents obtained by Retraction Watch through a  public records request, in 2015 Yao confessed to selectively choosing data in an email to the whistleblower. Continue reading Florida researcher “cherry picked” data, university investigation finds

Unnamed institution makes baffling retraction requests, journals comply

Two journals are retracting papers published by researchers affiliated with Children’s Hospital Los Angeles (CHLA).

To be frank, we’re baffled by most of this story. The retraction notices say “the institution” requested the retractions, but don’t name it; the first and last authors are also affiliated with the University of Southern California, as well as CHLA. Neither journal will say which institution sent the request, and USC and CHLA have each declined to comment on the retractions.

Here’s what we do know: Continue reading Unnamed institution makes baffling retraction requests, journals comply

Retract, replace, retract: Beleaguered food researcher pulls article from JAMA journal (again)

Brian Wansink

A high-profile food researcher who’s faced heavy criticism about his work has retracted the revised version of an article he’d already retracted last month.

Yes, you read that right: Brian Wansink at Cornell University retracted the original article from JAMA Pediatrics in September, replacing it with a revised version. Now he’s retracting the revised version, citing a major error: The study, which reported children were more likely to choose an apple over a cookie if the apple included an Elmo sticker, was conducted in children 3-5 years old, not 8-11, as the study reported.

Although Wansink told BuzzFeed he asked the journal to retract the paper, Annette Flanagin, Executive Managing Editor for The JAMA Network, told us the editors requested the retraction:

Continue reading Retract, replace, retract: Beleaguered food researcher pulls article from JAMA journal (again)

Caught Our Notice: Another retraction for researcher paid $100k to leave uni

Via Wikimedia

When Retraction Watch began in 2010, our co-founders Ivan Oransky and Adam Marcus quickly realized they couldn’t keep up with the hundreds of retractions that appeared each year.  And the problem has only gotten worse — although we’ve added staff, the number of retractions issued each year has increased dramatically. According to our growing database, just shy of 1,000 retractions were issued last year (and that doesn’t include expressions of concern and errata). So to get new notices in front of readers more quickly, we’ve started a new feature called “Caught our Notice,” where we highlight a recent notice that stood out from the others. If you have any information about what happened, feel free to contact us at [email protected].

Title:  Diabetes and Overexpression of proNGF Cause Retinal Neurodegeneration via Activation of RhoA Pathway  and  Diabetes-Induced Superoxide Anion and Breakdown of the Blood-Retinal Barrier: Role of the VEGF/uPAR Pathway 

What caught our attention:

Continue reading Caught Our Notice: Another retraction for researcher paid $100k to leave uni

Division director leaving U.S. research watchdog after nearly 15 years

Susan Garfinkel

The director of the Division of Investigative Oversight at the U.S. Office of Research Integrity is leaving the agency.

Susan Garfinkel told Retraction Watch that her last day is November 10. She is taking a position as assistant vice president in the Office of Research Compliance at The Ohio State University (OSU).

Garfinkel declined to comment on why she was leaving the agency:

Continue reading Division director leaving U.S. research watchdog after nearly 15 years

Are rich people meaner? While trying to find out, two teams find errors in each other’s work

Is having money linked to bad behavior?

A high profile paper published in 2012 in the Proceedings of the National Academy of Sciences (PNAS) set out to answer that question — and found that yes, the more money people have, the more likely they are to lie, cheat, and steal. And the greedier they are, the worse they behave. But when a more recent paper tried to replicate some of those findings, it couldn’t.

It turns out, both the original paper and the paper that tried to replicate it contained errors. Although neither appear to affect the main conclusions, the authors of the 2016 replication recently issued a correction; the error in the 2012 paper was initially deemed too insignificant to correct, but the journal has decided to revisit the idea of issuing a correction.

A representative of PNAS told us that the replication paper — and reporting by Retraction Watch — is the reason why: Continue reading Are rich people meaner? While trying to find out, two teams find errors in each other’s work

An accomplished philosopher invented a pseudonym. Why?

Amélie Rorty

In 1980, Leila Tov-Ruach published a book chapter in which she thanked the editor of the book, Amélie Oksenberg Rorty, “for the hospitality that made the writing of this paper possible.”

Normally, such an acknowledgement wouldn’t raise eyebrows. But, the trouble is, Tov-Ruach and Rorty are the same person:  Leila Tov-Ruach is a pseudonym for Rorty, an accomplished philosopher. The University of California Press (UC Press) officially outed Rorty as Leila Tov-Ruach when it issued corrections for two chapters she published decades ago under the pseudonym (1, 2).

The corrections explain the author of the chapters is Rorty, who also edited the two books in which the chapters appear. Although Rorty didn’t note in the original versions of the books that she is Tov-Ruach, she has not tried to hide her pseudonym either.  She has acknowledged she is Tov-Ruach in her CV, and at least some philosophers know about the pseudonym (1, 2).

Why would a philosopher—who has an impressive publishing record that spans 50 years and, at 85 years old, is still a lecturer at Harvard—choose to write under a fake name?

Continue reading An accomplished philosopher invented a pseudonym. Why?

Journal issues note of concern, tips off university’s research integrity office

A journal has published an expression of concern (EoC) for a paper on cancer genetics in mice, over a concern about data in some gel panels.

The EoC for “Suppression of intestinal tumorigenesis in Apc mutant mice upon Musashi-1 deletion,” appeared Sept. 21 in Journal of Cell Science (JCS).

With the notice, the journal says:

Continue reading Journal issues note of concern, tips off university’s research integrity office