Category: the netherlands

Given “wrong pathology slides,” heart journal retracts paper

A cardiology journal has retracted a paper after the authors were unable to provide correct pathology slides to replace the wrong ones submitted with the original manuscript.

The paper is titled “Aortic Valve Endocarditis and Coronary Angiography With Cerebral Embolic Protection,” published on April 10, 2017 in The Journal of the American College of Cardiology: Cardiovascular Interventions (JACC:CI). It has not yet been cited, according to Clarivate Analytics’ Web of Science.

JACC:CI retracted the paper on Aug. 14, providing this notice: Continue reading Given “wrong pathology slides,” heart journal retracts paper

Genetic disorder gets name change, but patient’s father still not happy

Credit: Online Mendelian Inheritance in Man

The leading genetic disease database has chosen a new name for a genetic condition, following complaints from a man whose son has the condition.

On Aug. 11, 2017, two days after our coverage of the situation, the Online Mendelian Inheritance in Man (OMIM) database changed the primary name of the phenotype associated with mutations in the RPS23 gene. The new name describes a set of features: “Brachycephaly, Trichomegaly, and Developmental Delay,” or BTDD.

Brachycephaly describes a condition where the back of the head is abnormally flat and trichomegaly refers to extra length, curling, pigmentation, or thickness of the eyelashes.

Marc Pieterse, of the Netherlands, has a son with the rare RPS23 mutation, one of two known patients in the world. The mutation affects ribosomes, cell components involved in protein production. On Aug. 9, we reported on Pieterse’s crusade against OMIM’s original name for the condition, which dubbed it a syndrome. He has feared that calling it a syndrome would “stigmatize” his son’s condition and tried to get the paper underpinning the OMIM entry retracted. The American Journal of Human Genetics has said it will not retract the paper.

Continue reading Genetic disorder gets name change, but patient’s father still not happy

Fearing “stigmatization,” patient’s father seeks retraction of paper on rare genetic mutation

The father of a boy with a rare genetic mutation has accused a scientist of exploiting his child by proclaiming the defect a “genetic syndrome” and naming it after herself.

At an impasse with scientists investigating, publicizing, and interpreting his son’s condition, the father seems willing to use any leverage he can muster to remove the “syndrome” entry in an online genetic disease database. Based solely on an email he obtained from the database director, the father became convinced that if the paper underpinning the entry were retracted, the syndrome would go down with it. So earlier this year, he withdrew his consent and asked the journal that published the paper for a retraction, based on improper patient consent. He has also threatened to lob accusations of research misconduct at the paper’s last author. Continue reading Fearing “stigmatization,” patient’s father seeks retraction of paper on rare genetic mutation

Publisher won’t retract two papers, despite university’s request

Jens Förster

Jens Förster, a high-profile social psychologist, has agreed to retract multiple papers following an institutional investigation — but has also fought to keep some papers intact. Recently, one publisher agreed with his appeal, and announced it would not retract two of his papers, despite the recommendation of his former employer.

Last month, the American Psychological Association (APA) announced it would not retract two papers co-authored by Förster, which the University of Amsterdam had recommended for retraction in May, 2015. The APA had followed the university’s advice last year and retracted two other papers, which Förster had agreed to as part of a settlement with the German Society for Psychology (DGPs). But after multiple appeals by Förster and his co-authors, the publisher has decided to retain the papers as part of the scientific record.

Many voices contributed to the discussion about these two papers — in November, 2016, the University of Amsterdam announced it was rejecting the appeal by another co-author on both papers, Nira Liberman, based at Tel Aviv University in Israel. The following month, Tel Aviv University announced that it believed the articles should not be retracted, based on its own internal review.

The APA reviewed the various recommendations, according to last month’s announcement:

Continue reading Publisher won’t retract two papers, despite university’s request

It’s not just whistleblowers who deserve protection during misconduct investigations, say researchers

Sven Hendrix
Lex Bouter

In 2010, the former PhD supervisor of Sven Hendrix, a neuroanatomist at Hasselt University in Belgium, was accused of misconduct. Although the allegations were eventually dropped, the experience was emotionally and professionally draining – and Hendrix wanted the research community to know about it. In 2015, he shared his story at a conference in Rotterdam; in the audience was Lex Bouter at Vrije Universiteit in Amsterdam, who works on research integrity (and is co-chair of this year’s World Conference on Research Integrity [WCRI], happening now). Bouter invited Hendrix to write a paper with him. This month, Accountability in Research published “Both Whistle Blowers and the Scientists They Accuse are Vulnerable and Deserve Protection,” an abstract of which is being presented today at the WCRI. We spoke with Hendrix and Bouter about their paper.

Retraction Watch: The title of your paper kind of says it all. Can you say more about what prompted you to write it?

Continue reading It’s not just whistleblowers who deserve protection during misconduct investigations, say researchers

“Think of the unthinkable:” JAMA retraction prompts author to urge others to share data

A few months ago, a researcher told Evelien Oostdijk there might be a problem with a 2014 JAMA study she had co-authored.

The study had compared two methods of preventing infection in the intensive care unit (ICU). But a separate analysis had produced different results.

Oostdijk, from the University Medical Center Utrecht in The Netherlands, immediately got to work to try to figure out what was going on. And she soon discovered the problem: The coding for the two interventions had been reversed at one of the 16 ICUs. This switch had “a major impact on the study outcome,” last author Marc Bonten, also from the University Medical Center Utrecht, wrote in a blog post about the experience yesterday, because it occurred at “one of the largest participating ICUs.”

When Oostdijk and a researcher not involved in the study analyzed the data again, they discovered a notable difference between the revised and original findings: The new analysis revealed that one of the interventions had a small but significant survival benefit over the other.

Oostdijk and Bonten, who supervised the re-analysis, notified their colleagues of the revised study outcomes and contacted the journal requesting a retraction and replacement, which was published yesterday in JAMA.

According to the notice of retraction and replacement:

Continue reading “Think of the unthinkable:” JAMA retraction prompts author to urge others to share data

What leads to bias in the scientific literature? New study tries to answer

By now, most of our readers are aware that some fields of science have a reproducibility problem. Part of the problem, some argue, is the publishing community’s bias toward dramatic findings — namely, studies that show something has an effect on something else are more likely to be published than studies that don’t.

Many have argued that scientists publish such data because that’s what is rewarded — by journals and, indirectly, by funders and employers, who judge a scientist based on his or her publication record. But a new meta-analysis in PNAS is saying it’s a bit more complicated than that.

In a paper released today, researchers led by Daniele Fanelli and John Ioannidis — both at Stanford University — suggest that the so-called “pressure-to-publish” does not appear to bias studies toward larger so-called “effect sizes.” Instead, the researchers argue that other factors were a bigger source of bias than the pressure-to-publish, namely the use of small sample sizes (which could contain a skewed sample that shows stronger effects), and relegating studies with smaller effects to the “gray literature,” such as conference proceedings, PhD theses, and other less publicized formats.

However, Ferric Fang of the University of Washington — who did not participate in the study — approached the findings with some caution:

Continue reading What leads to bias in the scientific literature? New study tries to answer

Journals flag two papers by psychologist Jens Förster

forster-j-a1Journals have flagged two papers by prominent social psychologist Jens Förster — whose work has been subject to much scrutiny — over concerns regarding the validity of the data. 

Förster already has three retractions, following an investigation by his former employer, the University of Amsterdam (UvA) in the Netherlands. In 2014, we reported on the first retraction for Förster for one of three studies with odd patterns that were flagged by the UvA investigation, a 2012 paper in Social Psychological and Personality Science; subsequently, the Netherlands Board on Research Integrity concluded that data had been manipulated. Three statistical experts from the UvA then carried out a more in-depth analysis of 24 publications by Förster, and found eight to have “strong evidence for low scientific veracity.”

Last year, Förster agreed to retract two more papers as part of a deal with the German Society for Psychology (DGPs); those retractions appeared earlier this year. All three papers that Förster has lost until now are from the “strong evidence for low scientific veracity” category. Recently, two more of Förster’s papers from the same category were flagged with notices, but not retracted.

One “statement of institutional concern,” issued by Personality and Social Psychology Bulletin, reads:
Continue reading Journals flag two papers by psychologist Jens Förster

No academic post for fraudster Diederik Stapel, after all

stapel_npc
Diederik Stapel

Recently, we reported that social psychologist and renowned data faker Diederik Stapel had found himself a new gig supporting research at a vocational university in the Netherlands — but it appears that was short-lived.

According to multiple news reports, NHTV Breda will not be employing Stapel, after all.

Here’s our Google translate of a portion from De Telegraaf: Continue reading No academic post for fraudster Diederik Stapel, after all

He’s back: Data faker Diederik Stapel will support research at vocational university

Diederik Stapel
Diederik Stapel

Diederik Stapel, the social psychology researcher who has had 58 papers retracted after admitting that he made up the data, has a new job: helping other researchers.

Stapel, according to BN DeStem (via Google Translate), Continue reading He’s back: Data faker Diederik Stapel will support research at vocational university