Child took wrong compound for over a year after “communication error”

Credit: Steven Depolo, Flickr

A journal is retracting a paper after it discovered researchers gave a child the wrong supplement for more than a year.

Rhiannon Bugno, managing editor for Biological Psychiatry, told Retraction Watch the mix-up did not put the patient at risk. However, the mistake was enough for the journal’s editor, John Krystal, of Yale University, to request the retraction of a 2016 paper describing the young girl’s experience taking the compound,“Rett-like Severe Encephalopathy Caused by a De Novo GRIN2B Mutation Is Attenuated by D-serine Dietary Supplement.”

Originally published June 17, 2016, the paper was retracted Jan. 15. Led by corresponding author Xavier Altafaj, of the University of Barcelona (UB) and Bellvitge Biomedical Research Institute (IDIBELL), researchers described using an amino acid, D-serine, to treat a child with a rare genetic disorder that affects neurons.

According to the notice, the researchers did use D-serine in lab work used as proof-of-concept; however, when it came time to try it in the patient, as a result of a “communication error:”

Continue reading Child took wrong compound for over a year after “communication error”

Caught Our Notice: Bioethics article retracted for…ethics violation

Title: Bioethics and Medical Education

What Caught Our Attention: As we’ve said before, you can’t make this stuff up: An article on bioethics had its own ethical issues to deal with. It turns out, the authors had “substantial unreferenced overlap” with another article, that “overlap” including the article’s title. Here’s a side by side comparison of the first page, highlighting the matching text: Continue reading Caught Our Notice: Bioethics article retracted for…ethics violation

Is plagiarism a problem in economics? Survey of editors says … yes

Gary Hoover

In 2004, a survey of editors of economic journals found 3 out of 10 had seen at least one case of plagiarism within the past year. More than a decade later, has the problem gotten better? Or worse? Gary Hoover at the University of Oklahoma, who co-authored the 2004 paper, decided to revisit the issue by resurveying editors in economics, along with others working in different fields. What he found — and reported in Social Science Quarterly — was plagiarism is still a problem, which economists want to address.

Retraction Watch: Why did you want to revisit the findings from the 2004 survey of editors in economics 10 years later?

Continue reading Is plagiarism a problem in economics? Survey of editors says … yes

Data in biofuel paper “had either been grossly misinterpreted or fabricated”

A biology journal has retracted a 2011 paper after the University of California, Los Angeles determined that the data in three figures “cannot be supported.”

In February, the journal Applied and Environmental Microbiology retracted the paper, which explores efforts to engineer bacteria to convert plant biomass into biofuel.

Claudia Modlin, assistant director of UCLA’s Office of Research Policy and Compliance, told Retraction Watch that the university informed the journal about the issues last October, after reviewing the work. Continue reading Data in biofuel paper “had either been grossly misinterpreted or fabricated”

Caught Our Notice: No retraction for “likely fraudulent” study

Title: Homocysteine as a predictive factor for hip fracture in elderly women with Parkinson’s disease

What Caught Our Attention:  In a letter to the editor, researchers led by Mark Bolland recently outlined the many reasons why a study by Yoshihiro Sato and colleagues in The American Journal of Medicine was “unreliable,” including evidence that the patient numbers were not achievable as described, and inconsistencies and errors in the study data. And let’s not forget a 2016 analysis (co-authored by Bolland) which cast doubt on Sato’s body of work, suggesting that more than 30 of his papers could be problematic. Continue reading Caught Our Notice: No retraction for “likely fraudulent” study

Probe into Carlo Croce reached “defensible and reasonable” decisions, says external review

An independent analysis of how The Ohio State University reviewed allegations of misconduct against a high-profile cancer researcher has found that the institution “complied with applicable law and with relevant institutional policies and reached reasoned and supportable conclusions.”

The review follows numerous allegations of research misconduct against Carlo Croce, described in a March 8 story in the New York Times. According to the Times article, Croce has been the subject of multiple investigations; at least five of those inquiries from OSU cleared him of wrongdoing. 

Croce has denied the allegations, and is now suing the New York Times and an outside researcher who served as a key source in the story. As a result of the story, however, OSU — where Croce is basedtold us last year it had “launched an independent review of our systems for ensuring research integrity.”

Continue reading Probe into Carlo Croce reached “defensible and reasonable” decisions, says external review

Retraction count for Italian researcher swells to 15 as five papers fall

A researcher who is facing a criminal investigation in Italy for research misconduct has seen five more papers retracted, for a total of 16 15.

Molecular and Cellular Biology has retracted four papers published between 1987 to 2001 by Alfredo Fusco, a cancer researcher in Italy; the Journal of Virology retracted one 1985 paper. Fusco was first author on two papers and last author on three. Both journals are published by The American Society for Microbiology (ASM), which issued identical retraction notices for all five papers, mentioning “evidence of apparent manipulation and duplication.”

Carlo Croce, a cancer researcher now at the Ohio State University, who has been dogged by misconduct allegations, co-authored one of the papers.  Croce now has eight retractions.

Here’s the notice presented for all five retractions: Continue reading Retraction count for Italian researcher swells to 15 as five papers fall

A “GROSS CASE OF PLAGIARISM:” How did one Elsevier journal plagiarize another?

Nicholas Peppas

When Nicholas Peppas, chair of engineering at the University of Texas at Austin, discovered one of his papers had been plagiarized, he decided to “go public!”

On February 27, Peppas tweeted about a “gross case of plagiarism:” He alleged a 2013 review published in Saudi Pharmaceutical Journal had directly copied sections of his 2011 review in Advanced Drug Delivery Reviews—both published by Elsevier. (The tweet includes a side-by-side image of a section of the two texts.) Continue reading A “GROSS CASE OF PLAGIARISM:” How did one Elsevier journal plagiarize another?

“Ethical shades of gray:” 90% of researchers in new health field admit to questionable practices

Anthony R. Artino, Jr.

It’s always interesting to know how many researchers in any given field engage in so-called questionable research practices that don’t rise to the level of out-and-out fraud: honorary authorship, citing articles they don’t read, choosing reference lists that would please editors or reviewers, for instance. And when the researchers work in a field with potential health implications, the findings are even more compelling. Lauren Maggio and Anthony R. Artino, Jr. from the Uniformed Services University spoke to us recently about the findings from their survey (posted in bioarXiv) of health professions education researchers, a relatively new field that studies how future health professionals are trained.

Retraction Watch: You note that 90% of the people who volunteered to complete the survey admitted to at least one questionable research practice. Was that surprising?

Continue reading “Ethical shades of gray:” 90% of researchers in new health field admit to questionable practices

New tool looks for signs of image doctoring

Mary Walsh

One of the most common reasons for retractions is image manipulation. When searching for evidence of it, researchers often rely on what their eyes tell them. But what if screening tools could help? Last week, researchers described a new automated tool to screen images for duplication (reported by Nature News); with help from publishing giant Elsevier, another group at Harvard Medical School is developing a different approach. We spoke with creators Mary Walsh, Chief Scientific Investigator in the Office for Professional Standards and Integrity, and Daniel Wainstock, Associate Director of Research Integrity, about how the tool works, and why — unlike the other recently described automated tool — they want to make theirs freely available.

Retraction Watch: What prompted you to develop this tool?

Continue reading New tool looks for signs of image doctoring