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Nature Cell Biology insulin paper retracted over antibody problems

nature cell biologyA Nature Cell Biology article on insulin regulation has been retracted after scientists noted that the antibodies used in their research were not as specific as they had previously believed.

The notice is clear on the problems with the science, which together “call into question the main conclusions of the paper.” Three of the paper’s five authors were employed at Novartis at the time of publication.

Here’s the notice for “Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion”: Continue reading Nature Cell Biology insulin paper retracted over antibody problems

“Incorrect data” kills apoptosis paper

Screen Shot 2014-12-19 at 5.52.16 PMFrontiers in Pharmacology has retracted a paper on baicalin, an antioxidant sold in health food stores, because it had both “incorrect data and invalid statistical analyses.”

A comment on PubPeer notes that one of the figures (see image to the right) contains two similar-looking flow cytometry images labeled with different values, which could be what the retraction is hinting at.

Here’s the notice for “Baicalin induced dendritic cell apoptosis in vitro”: Continue reading “Incorrect data” kills apoptosis paper

Paper recommending calorie limits on Happy Meals retracted

Image via Stefan

A paper estimating the effects of limiting fast food meals with toys to under 550 calories has been retracted after concerns arose regarding the scientists’ use of an outdated model for estimating weight changes in kids.

The paper estimated that kids who eat fast food twice a week would avoid gaining two pounds a year if calorie limits are imposed on meals with toys. However, everyone we spoke to, and the notice, indicated that their estimate was inaccurate.

Here’s the notice for “Modeling Potential Effects of Reduced Calories in Kids’ Meals with Toy Giveaways”:

Continue reading Paper recommending calorie limits on Happy Meals retracted

Paper that formed basis of study retracted earlier this year retracted itself, from Science

science dec 2014Back in May, we reported on a retraction from Molecular Cell that referred to a 2012 study the same group had published in Science. (A few weeks later, the lab head told us just how painful the process was.)

Now, the Science paper has been retracted. Here’s the notice: Continue reading Paper that formed basis of study retracted earlier this year retracted itself, from Science

Researchers retract paper for which first author won an award — but won’t sign notice

Bernasconi_Premio_Roche2012_small
Riccardo Bernasconi

Most of the authors of two Molecular Cell papers have retracted them after becoming aware of inappropriate image manipulation by the first author of both — who refused to sign the notices.

One of the papers, “Role of the SEL1L:LC3-I Complex as an ERAD Tuning Receptor in the Mammalian ER,” earned first author Riccardo Bernasconi, who successfully defended his PhD in 2010, the STSBC-Roche Diagnostics award in 2012. Here’s the notice for that paper: Continue reading Researchers retract paper for which first author won an award — but won’t sign notice

Elsevier retracting 16 papers for faked peer review

zaman
Khalid Zaman

Fake peer reviews: They’re all the rage.

Sixteen papers are being retracted across three Elsevier journals after the publisher discovered that one of the authors, Khalid Zaman, orchestrated fake peer reviews by submitting false contact information for his suggested reviewers.

This particular kind of scam has been haunting online peer review for a few years now, as loyal Retraction Watch readers know. This one is a classic of the genre: According to Elsevier’s director of publishing services, Catriona Fennell, an editor first became suspicious after noticing that Zaman’s suggested reviewers, all with non-institutional addresses, were unusually kind to the economist’s work.

Elsevier has actually hired a full-time staff member with a PhD in physics and history as a managing editor to do the grunt work on cases like this. Flags were first raised in August, at which point the ethics watchdog went to town digging through all of Zaman’s other publications looking for suspicious reviews coming from non-institutional addresses provided by the scientist, an economist at COMSATS Information Technology Center in Abbottabad, Pakistan.

Here’s the main notice: Continue reading Elsevier retracting 16 papers for faked peer review

That new beetle? Actually, it’s really an old beetle

Acanthophorus_serraticornis
Acanthophorus serraticornis via Wikimedia Commons.

A team of entomologists in India had to put their new species celebration on hold last year, when they found out their discovery had already been discovered.

The Journal of Insect Science paper, initially published in December 2012, was retracted in October 2013, after several entomologists confirmed that the beetle was actually a previously identified species called Acanthophorus serraticornis. (The notice has a November 2014 date, but we understand that’s because the journal switched servers.)

Here’s the notice for “A new record of longicorn beetle, Acanthophorus rugiceps, from India as a root borer on physic nut, Jatropha curcas, with a description of life stages, biology, and seasonal dynamics”: Continue reading That new beetle? Actually, it’s really an old beetle

Stem cell researcher retracts neuron paper for “image aberrations”

embo journalJens Christian Schwamborn, a stem cell researcher at the University of Luxembourg, is retracting a 2007 paper on how to grow brain cells.

The paper, “Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity,” was published while Schwamborn was at Westfälische Wilhelms‐Universität Münster in Germany. An anonymous critic had sent questions about the study to Germany’s DFG in the middle of last year, and later to Paul Brookes, who posted them on PubMed Commons.

Those criticisms match the problems listed in the detailed notice: Continue reading Stem cell researcher retracts neuron paper for “image aberrations”

Stem cell researcher Hanna “working…to correct the unfortunate and inadvertent mistakes” in papers

jacob
Jacob Hanna

Jacob Hanna of Israel’s Weizmann Institute has been a media darling for years, including as a member of the 2010 Technology Review 30 under 35 for his work with stem cells.

However, questions have been mounting about his research, both on PubPeer (which has critical comments for 15 papers he’s an author on) and in other stem cell labs, who have not been able to reproduce much of Hanna’s work.

We asked Hanna about a PubPeer entry specific to a 2005 paper in Blood. Commenters have accused the authors of figure manipulation and possible data republication. Here’s a figure from that post: Continue reading Stem cell researcher Hanna “working…to correct the unfortunate and inadvertent mistakes” in papers

Mix-and-match text topples microbiome paper

iemA group of gastroenterology researchers in Italy has lost their 2010 paper in Internal and Emergency Medicine, the journal of the Italian Society of Internal Medicine, for plagiarizing and duplicate publication.

The article, “Gut microbiota and related diseases: clinical features,” was published as a supplement by a team from the University of Bologna. Its conclusions: Continue reading Mix-and-match text topples microbiome paper