Nature Biotechnology has issued an editorial expression of concern (EOC) for a widely criticized study describing a potentially invaluable new lab tool.
The EOC mentions the lack of reproducibility of the gene-editing technique, known as NgAgo. Alongside it, the journal has published a correspondence which includes data from three separate research groups that cast doubt on the original findings.
According to a spokesperson for the journal, some of the paper’s authors have objected to the decision to issue an EOC.
Earlier this month, we reported on a letter signed by 20 researchers which also raised concerns about the genome-editing activities of NgAgo — and alleged the lab that produced the initial results turned away investigators when they attempted to validate the tool in mammalian cells.
Here’s the EOC, published yesterday: Continue reading Controversial gene-editing study flagged by Nature journal


Recently, the editors of a journal about management science received a submission from a prominent Dutch economist. But something didn’t feel right about it.

Circumcision is a hot topic. So hot, questions about a reviewer’s potential conflict with the author of an article promoting circumcision prompted a journal editor to resign, and one academic to call another a “fanatic.”
In March, 2013, a graduate student joined the lab of a prominent researcher in Australia, investigating new therapies for Parkinson’s. A few months later, everything fell apart.
Last week, we learned a 2016 paper heavily discussed on PubPeer 