Category: by author

Anil Potti failed to disclose corporate ties in yet-to-be-retracted JAMA papers

Anil Potti, the former cancer researcher whose work has become the subject of intense scrutiny that has already led to the retraction of five papers, didn’t tell the Journal of the American Medical Association (JAMA) about two very relevant corporate relationships he had when he published papers there, Retraction Watch has learned.

JAMA has published two papers by Potti and colleagues: 2008’s “Gene Expression Signatures, Clinicopathological Features, and Individualized Therapy in Breast Cancer,” and 2010’s “Age- and Sex-Specific Genomic Profiles in Non-Small Cell Lung Cancer.”

The Cancer Letter, which has been way out front in the Potti case, first reported Potti’s relationships with Eli Lilly and CancerGuide Diagnostics (formerly Oncogenomics, Inc.). As The Chronicle, Duke’s student newspaper, reported last September, the two companies cut their ties with Potti in July 2010 after allegations of misconduct and lying about a Rhodes Scholarship came to light.

But that was after the two papers were published, and Potti had relationships with both since 2006. As The Chronicle notes, he was a director at CancerGuide Diagnostics (formerly Oncogenomics, Inc.), and Continue reading Anil Potti failed to disclose corporate ties in yet-to-be-retracted JAMA papers

Montreal Heart Institute researcher dismissed following two retractions for image manipulation

A Montreal Heart Institute researcher who retracted two papers less than a month ago has been fired from his post.

Zhiguo Wang, who had been funded by the Canadian Institute of Health Research and the Canadian Diabetes Association, studied the genes linked to heart rhythm abnormalities, among other subjects. Wang also has an appointment at the University of Montreal.

As first reported in Retraction Watch, Wang withdrew two papers for the Journal of Biological Chemistry (JBC) in the journal’s August 12 issue. The story was quickly picked up by Postmedia and the CBC. At the time, Wang told us: Continue reading Montreal Heart Institute researcher dismissed following two retractions for image manipulation

The $240,000 retraction: Scientist responsible gives back company shares

In December, we reported on how a Swedish company that was about to go public dealt with a retraction of a paper in the Proceedings of the National Academy of Sciences (PNAS) that formed some of the basis of their work. The company, Wnt Research, was scheduled to go public on November 26, 2010, but after the retraction appeared on November 11, they postponed the initial public offering (IPO), and let every investor that had expressed an interest know about the retraction.

We thought the company’s moves demonstrated a remarkable transparency. Now we learn that the scientist responsible for the errors that led to the retraction has given back the shares which he or she was given when the company was founded. The company announced the news in a press release last week: Continue reading The $240,000 retraction: Scientist responsible gives back company shares

Imperial committee to weigh “validity” of Ahluwalia’s PhD following second retraction

Earlier this week, we reported on the retraction of another paper by Jatinder Ahluwalia, whose record of misconduct has left marks at Cambridge and University College London. Today, a spokesperson for Imperial College London, where the soon-to-be-retracted work formed the basis of Ahluwalia’s PhD, tells Retraction Watch that a committee will review Ahluwalia’s doctorate: Continue reading Imperial committee to weigh “validity” of Ahluwalia’s PhD following second retraction

Another retraction for Jatinder Ahluwalia, in Journal of Neurochemistry

The Journal of Neurochemistry will retract a paper by Jatinder Ahluwalia, the scientist who recently left his post at the University of East London following an investigation into his work.

Ahluwalia was lead author of the 2003 paper, “Activation of capsaicin-sensitive primary sensory neurones induces anandamide production and release,” while earning his PhD at Imperial College London. It had already been the subject of a June 2010 correction. That correction blamed the paper’s problems on a typo:  Continue reading Another retraction for Jatinder Ahluwalia, in Journal of Neurochemistry

New retractions of diabetes, cardiovascular papers from Japan involve repeat use of figures

At least four retractions have appeared involving the work of a group of Japanese researchers who appear to have reused figures — and doctored them — in multiple manuscripts.

The authors, led by Yoshiyuki Hattori, of Dokkyo University School of Medicine in Mibu (whose motto, by the way, is “where character is developed through learning” a reader points out that we had the wrong Dokkyo initially), published the same figure twice, and in the same year, in the Journal of Cardiovascular Pharmacology and Biochimica et Biophysica Acta.

Here’s a retraction notice from the JCP: Continue reading New retractions of diabetes, cardiovascular papers from Japan involve repeat use of figures

A fifth retraction for Anil Potti, this one in Blood

courtesy Duke

The list of papers retracted by former Duke oncologist Anil Potti has grown to five. The notice, from Blood: Continue reading A fifth retraction for Anil Potti, this one in Blood

Is it time for a Retraction Index?

We often hear — with data to back the statement — that top-tier journals, ranked by impact factor, retract more papers than lower-tier journals. For example, when Murat Cokol and colleagues compared journals’ retraction numbers in EMBO Reports in 2007, as Nature noted in its coverage of that study (h/t Richard van Noorden):

Journals with high impact factors retract more papers, and low-impact journals are more likely not to retract them, the study finds. It also suggests that high- and low-impact journals differ little in detecting flawed articles before they are published.

One thing you notice when you look at Cokol et al’s plots is that although their models seem to take retractions “per capita” — in other words per study published — into account, they don’t report those figures.

Enter a paper published this week in Infection and Immunity (IAI) by Ferric Fang and Arturo Casadevall, “Retracted Science and the Retraction Index.” Continue reading Is it time for a Retraction Index?

Cal Poly Pomona education researcher leaves post after rampant plagiarism is revealed

In late June, we wrote about a case of wholesale plagiarism involving an education researcher in California, Thienhuong N. Hoang. Our post prompted a flurry of emails from readers cluing us in to other cases in which Hoang, of California State Polytechnic University in Pomona, had lifted essentially entire articles from other scholars and changed little, if anything, but the author information.

For example, Hoang’s “‘The Contributions of Teachers’ Credentialing Routes and Experience Levels on Classroom Management,” in the January 2009 issue of the International Journal of Instruction, was the same, nearly word-for-word, as the work of two other authors, “Exploring the relationship between certification sources, experience levels, and classroom management orientations of classroom teachers,” published in Teaching and Teacher Education in 2007.

The International Journal of Instruction has removed the article from its archive and placed this announcement on its site: Continue reading Cal Poly Pomona education researcher leaves post after rampant plagiarism is revealed

Authors retract two JBC papers on how heart rhythms go awry; Montreal Heart Institute looking into why

The authors of two Journal of Biological Chemistry (JBC) studies of the molecular underpinnings of hearts whose rhythms have gone awry have retracted the papers, for reasons that are not completely clear.

The two papers are  “MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts,” published in 2007, and “Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart,” published in 2008.

This being the JBC, the retraction notices in the August 12, 2011 issue say nothing: Continue reading Authors retract two JBC papers on how heart rhythms go awry; Montreal Heart Institute looking into why