Category: by author

2001 Fujii papers retracted — finally. What took so long?

BJO

Nearly four years after an analysis of more than 160 papers by Yoshitaka Fujii concluded the chances the data were authentic were infinitesimally small, the British Journal of Ophthalmology has decided to formally retract one of the papers included in that review.

The name Yoshitaka Fujii should ring a bell — an alarm bell, in fact — for our readers. He’s firmly listed in the number one spot on our leaderboard, with more than 180 retractions.

The recently retracted paper — “Ramosetron compared with granisetron for the prevention of vomiting following strabismus surgery in children” — has been included in that retraction total for years, because it was part of a seminal 2012 analysis by J.B. Carlisle that put the odds of data occurring naturally in some of Fujii’s papers at: Continue reading 2001 Fujii papers retracted — finally. What took so long?

Karolinska may reopen inquiry into star surgeon Macchiarini, following documentary’s revelations

dr-paolo-macchiarini
Paolo Macchiarini

Karolinska Institutet may reopen its misconduct investigation into acclaimed surgeon Paolo Macchiarini following new allegations revealed during a documentary series by Swedish Television.

According to a recent statement from KI: Continue reading Karolinska may reopen inquiry into star surgeon Macchiarini, following documentary’s revelations

Lancet retracts 24-year-old paper by “father of nutritional immunology” after reopening inquiry

lancetFollowing questions from outside experts, a retraction of a related paper, a university investigation and a court case, The Lancet has decided to retract a 1992 paper by Ranjit Kumar Chandra, the self-proclaimed “father of nutritional immunology.”

In a lengthy retraction note included in the January 30 issue, the journal explains that:

the balance of probabilities in our judgment is that the reliability of the 1992 Lancet paper by Chandra can no longer be assured.

Chandra is objecting to the retraction.

This retraction was a long time coming, so sit back and relax as we fill in the backstory. Continue reading Lancet retracts 24-year-old paper by “father of nutritional immunology” after reopening inquiry

EMBO takes back Voinnet’s award, investigates other awardee who just lost a Nature Genetics paper

Screen Shot 2016-01-28 at 11.41.20 AMEMBO has taken back an award given to beleaguered plant biologist Olivier Voinnet in 2009, and is investigating a recent grantee who had a paper retracted from Nature Genetics yesterday.

The European Molecular Biology Organization (EMBO) “promotes excellence in the life sciences” in Europe, in part by awarding prizes to promising young scientists. Voinnet and Sonia Melo earned their awards by exhibiting potential as young scientists studying genetics — of plants and cancer, respectively — but now EMBO is skeptical of the papers that formed the basis of their applications.

Melo’s Installation Grant from EMBO was announced just last month, and consists of 50,000 Euros annually for three to five years. She is currently based at the University of Porto, in Portugal.

Voinnet’s problems are well-documented on this blog — 21 corrections, seven retractions, and two investigations. Earlier this week, we reported that the Swiss National Science Foundation had cut off Voinnet’s funding, and banned him for three years. Continue reading EMBO takes back Voinnet’s award, investigates other awardee who just lost a Nature Genetics paper

Sharing data is a good thing. But we need to consider the costs.

Liz Wager

Last week, the International Committee of Medical Journal Editors proposed requiring authors to share deidentified patient data underlying the published results of clinical trials within six months of publication. The proposal has earned much support but also some concerns – for example that other scientists might poach the findings, acting as the New England Journal of Medicine dubbed “research parasites.” Elizabeth Wager, a member of the board of directors of our parent organization, disagrees with that concern, but raises another issue – namely, the unintended consequences of data sharing on other, more effective initiatives to make reporting more transparent.

The recent proposal from the ICMJE may appear, at first glance, a positive step towards better clinical trial reporting. However, I’m concerned that this new requirement might undermine other more effective initiatives to increase the efficiency of research, such as the publication of protocols and full study reports. Here’s why.

All actions have costs, risks, and benefits: Making partial data sharing a condition of publication is no exception. The costs are hard to quantify but undoubtedly not trivial.  Putting clinical data into a usable format and making it meaningful to other researchers requires considerable time and effort by knowledgeable people. To this must be added the costs of establishing and maintaining suitable repositories and of checking compliance.

I’m not saying that open data does not have any benefits. Continue reading Sharing data is a good thing. But we need to consider the costs.

Seralini paper claiming GMO toxicity disappears after journal domain expires

SJASA paper claiming genetically modified corn may be toxic over long periods has disappeared one day after it was presented at a press conference, after the journal’s domain name expired.

The paper, co-authored by Gilles Seralini — who has published controversial research showing harms of GM food — appeared in the Scholarly Journal of Agricultural Sciences (SJAS). On Tuesday, the Committee for Independent Research and Information on Genetic Engineering (Criigen) scheduled a press conference about the findings, noting the finding presented

new scientific data on Bt toxins and a thorough study of the records show that this GMO Bt maize is most probably toxic over the long term.

But on Wednesday January 27, the journal’s domain name expired. This isn’t a retraction per se, but a disappearance. Now, any link to the study “Pathology reports on the first cows fed with Bt176 maize (1997–2002)” goes to this page, which says in the bottom right corner: Continue reading Seralini paper claiming GMO toxicity disappears after journal domain expires

Following an earlier investigation, GW biologist earns two expressions of concern

3.cover (1)The Journal of Biological Chemistry has flagged two papers by a George Washington University cancer biologist with expressions of concern, following an investigation completed by the university in 2014.

The notes contain little specific information; all we know is that there are questions about the data and conclusions in the papers.

The last author on both papers is Rakesh Kumar, who adds these EoCs to a count that includes, according to our records, three retractions and five corrections. Plus an $8 million lawsuit against his employer for emotional distress when they put him on leave from his position as department chair.

The studies — “Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator” and “Regulation of NF-B circuitry by a component of the nucleosome remodeling and deacetylase complex controls inflammatory response homeostasis” — have been cited 22 times and 33 times respectively, according to Thomson Scientific’s Web of Knowledge.

The expression of concern is the same for both papers — and matches others that we’ve seen from JBC:

Continue reading Following an earlier investigation, GW biologist earns two expressions of concern

Swiss funding agency cuts off Voinnet, bans him for 3 years

Olivier Voinnet
Olivier Voinnet

The Swiss National Science Foundation has stopped funding prominent plant scientist Olivier Voinnet, following months of questions about his work that have culminated in multiple retractions and corrections.

The agency confirmed to us that it has also banned Voinnet from seeking funding from the SNSF for three years.

We asked the SNSF the amount of funding Voinnet was receiving from SNSF at the time of this decision. They told us it was 1.25 million Swiss francs, equivalent to roughly the same in U.S. dollars.

By our count, Continue reading Swiss funding agency cuts off Voinnet, bans him for 3 years

Science publishes Voinnet’s 19th, 20th, and 21st corrections

351-6271-coverProminent plant biologist Olivier Voinnet has issued three more corrections in this week’s issue of Science.

Collectively, the papers have earned more than 1400 citations, according to Thomson Scientific’s Web of Knowledge.

By our count, he’s now at 21 corrections and seven retractions, following months of questions about his work. He’s been the subject of an investigation that found he “breached his duty of care,” and another which found evidence of scientific misconduct.

One correction goes against the recommendation of the ETH Commission to retract the paper for “well documented intentional manipulations.” According to the correction note, the incorrect figures did not “alter the data in any material way that could be construed to benefit the results and their conclusions.” That correction is the only one of the three for which Voinnet takes full responsibility.

The other two corrections place the responsibility on  Continue reading Science publishes Voinnet’s 19th, 20th, and 21st corrections

Lawsuit against Ole Miss for rescinded Sarkar job offer dismissed; briefs filed in PubPeer case

court caseWe recently obtained court documents showing that, in September, a judge dismissed a lawsuit filed by cancer researcher Fazlul Sarkar against the University of Mississippi after it rescinded a job offer after reviewing concerns raised about his research on PubPeer.

Sarkar’s connection to PubPeer will be familiar to many readers — he has also taken the site to court to force them to reveal the identity of the anonymous commenters who have questioned his findings. He has accused the commenters of defamation, arguing they cost him the job offer. Today, the American Civil Liberties Union filed a brief on behalf of PubPeer’s appeal of the court’s most recent ruling, that the site must disclose the identity of an anonymous commenter. At the same time, some heavy hitters in science – Bruce Alberts and Harold Varmus — and technology — Google and Twitter — filed briefs in support of the appeal.

The lawsuit against Ole Miss has brought to light the reasoning behind the school’s decision to rescind their offer to Sarkar — and the key role played by the concerns raised on PubPeer.

In a letter dated June 19, 2014 to Sarkar from Larry Walker, the director of the National Center for Natural Products Research at the University of Mississippi, Walker chides Sarkar for not revealing the extent of the ongoing questions over his research during the interview process:

Continue reading Lawsuit against Ole Miss for rescinded Sarkar job offer dismissed; briefs filed in PubPeer case