What does “reproducibility” mean? New paper seeks to standardize the lexicon

Science Translational MedicineWhat is the difference between “reproducible” and “replicable”? And how does each relate to results that are “generalizable” and “robust”?

Researchers are using these terms interchangeably, creating confusion over what exactly is needed to confirm a scientific result, argues a new paper published today in Science Translational Medicine.

Here’s how the US National Science Foundation (NSF) defines “reproducibility,” according to the authors: Continue reading What does “reproducibility” mean? New paper seeks to standardize the lexicon

Researcher who sued to stop retractions gets his sixth

Mario Saad
Mario Saad

A sixth retraction has appeared for a diabetes researcher who previously sued a publisher to try to stop his papers from being retracted.

Mario Saad‘s latest retraction, in PLOS Biology, stems from inadvertent duplications, according to the authors.  Though an investigation at Saad’s institution — the University of Campinas in Brazil — found no evidence of misconduct, a critic of the paper told The Scientist he does not believe that the issues with blots were inadvertent.

Previously, Saad sued the American Diabetes Association to remove four expressions of concern from his papers; they were later retracted, even though Unicamp recommended keeping three of them published.

Here’s the new retraction notice, for “Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice:” Continue reading Researcher who sued to stop retractions gets his sixth

Dutch university ordered to pay economist after she was accused of plagiarism

VU UniversityA court in the Netherlands has fined Vrije Universiteit Amsterdam (VU) 7,500 euros to compensate for “immaterial damage” to an economist accused of plagiarism.

Karima Kourtita researcher at VU, has been at the receiving end of anonymous complaints to her institution accusing her of plagiarism and her professor, high-profile economist Peter Nijkamp, of duplication (i.e. self-plagiarism). Kourtit is now seeking to prosecute the unnamed source of the complaint for defamation; the VU told us it will no longer accept fully anonymous complaints.

The case began when VU cancelled Kourtit’s thesis defense for plagiarism, and a report published on the VSNU, the Association of Universities, accused Nijkamp of self-plagiarism. Two of Nijkamp’s papers have been retracted as a result of the investigation; Kourtit is an author on one of the retracted papers.

A VU spokesperson told us:

Continue reading Dutch university ordered to pay economist after she was accused of plagiarism

Researcher who unsuccessfully sued journal to stop retractions earns another expression of concern

Mario Saad
Mario Saad

A journal has added expressions of concern (EOCs) to four papers about diabetes, including one co-authored by an author who previously sued a different journal when it took a similar action on his papers.

The Journal of Physiology flagged the papers after an investigation “could not rule out the possibility” that they contained duplicated Western blots. Though the three other papers do not include Mario Saad on their author list, he plays a role: The papers include blots duplicated from other papers of Saad’s. And they reveal that Saad may have published those blots multiple times in his own work.

The EOCs all start out with the same statement: Continue reading Researcher who unsuccessfully sued journal to stop retractions earns another expression of concern

Journal flags duplicated text by gynecologic cancer researcher with 13 retractions

cancers-logo

When journals discover duplicated material, many choose to retract — but a cancer journal recently faced with the same dilemma involving a researcher with multiple retractions under his belt has instead decided to flag the paper with an expression of concern.

An editor told us that Cancers considered retracting the paper, by gynecologic cancer researcher Noriyuki Takai, but decided not to because the paper

contains some novel content that is of interest to the scientific community.

Epigenetic Therapy in Human Choriocarcinoma,” published in 2010, has been cited once, according to Thomson Reuters Web of Science, and self-plagiarizes from other publications by Takai and his co-author, Hisashi Narahara. Both are researchers at Oita University in Japan.

Here’s the expression of concern:

Continue reading Journal flags duplicated text by gynecologic cancer researcher with 13 retractions

How much does a retracted result pollute the field?

Research Integrity and Peer Review

When a paper is retracted, how many other papers in the same field — which either cite the finding or cite other papers that do — are affected?

That’s the question examined by a study published in BioMed Central’s new journal, Research Integrity and Peer Review. Using the case of a paper retracted from Nature in 2014, the authors found that subsequent research that cites the retracted paper often repeats the problematic finding, thereby spreading it throughout the field. However, papers that indirectly cited the retracted result — by citing the papers that cited the Nature paper, but not the Nature paper itself — typically don’t repeat the retracted result, which limits its spread.

Here’s how the authors describe their findings in the paper: Continue reading How much does a retracted result pollute the field?

Macchiarini did not obtain necessary ethics approvals, says Swedish Research Council

lancetSurgeon Paolo Macchiarini did not apply for the necessary ethics approval to perform the pioneering transplants he’s known for, according to the Swedish Research Council.

Chief Legal Counsel Anna Hörnlund, who wrote a letter in this week’s The Lancet, says Macchiarini’s work needed to obtain ethical approval from one of six regional ethical review boards, as required by Swedish law — and neither Macchiarini nor his former employer, Karolinska Institutet, did so:

Continue reading Macchiarini did not obtain necessary ethics approvals, says Swedish Research Council

Retraction count for Shigeaki Kato climbs to 39

Shigeaki Kato
Shigeaki Kato

We’ve found another retraction for Shigeaki Kato, number seven on our leaderboard.

Our count for Kato has now risen to 39; we added five retraction notices to our count for Kato last month. These notices follow an investigation at the University of Tokyo, where Kato used to work, which found 43 papers contained “likely altered or forged materials,” according to a 2013 news article from The Asahi Shimbun.

Here’s the retraction note for “1alpha,25(OH)2D3-induced DNA methylation suppresses the human CYP271B1 gene,” published in Molecular and Cellular Endocrinology:

Continue reading Retraction count for Shigeaki Kato climbs to 39

Plant scientist Voinnet’s correction count grows to 22

nature structure molecular biologyWe have found another correction for high-profile plant scientist Olivier Voinnet, bringing his total count to 22. Voinnet, who works at ETH Zurich, also has seven retractions, a funding ban, and a revoked award.

Voinnet’s most recent corrections involve problems with figures; the same issue is cited in this latest correction notice, for “Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels.”

The correction notice in Nature Structural & Molecular Biology, issued earlier this year, explains:

Continue reading Plant scientist Voinnet’s correction count grows to 22