Category: basic life sciences retractions

Three expressions of concern added to cancer researcher’s notice list

3.coverQuestions about data and conclusions in papers by a cancer researcher at the University of Maryland have led to three expressions of concern in the Journal of Biological Chemistry.

The notices follow four retractions — two for image duplications and two for unknown reasons — for Anil K. Jaiswal. The three papers under notice are all on mechanisms that regulate gene expression; PubPeer commenters have raised questions about some of the figures in the papers.

The expression of concern on all three papers reads, in full:

Continue reading Three expressions of concern added to cancer researcher’s notice list

Robot for stroke patients paper copied 3 pages of equations

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A 2014 paper on a robotic system for patients who have had a stroke contains three pages of equations that are not original.

According to the retraction note, “Cascade controller design and stability analysis in FES-aided upper arm stroke rehabilitation robotic system” copied the equations from a paper that other researchers presented at a conference in 2012. The papers both describe a system that delivers a boost of electricity to stroke patients’ arms to help them perform a task.

Here’s the note, from Nonlinear Dynamics:

Continue reading Robot for stroke patients paper copied 3 pages of equations

Paper claiming GMO dangers retracted amid allegations of data manipulation

FNS2015012717103119A nutrition journal is retracting a paper about potential dangers of eating food containing genetically modified organisms (GMOs) for duplicating a figure, as news stories from Italy are reporting accusations that the last author falsified some of his research.

In the paper, Federico Infascelli, an animal nutrition researcher at the University of Naples, and his colleagues showed modified genes could wind up in the blood and organs of baby goats whose mothers ate GM soybeans. According to our Google Translate version of an article by Italian newspaper La Repubblica, an investigation suggests that Infascelli has manipulated images to suggest GMOs are harmful. He could face fines and be suspended from the university.

La Repubblica reports that a committee appointed by the rector of the university, Gaetano Manfredi, found errors in Infascelli’s data that suggested he had manipulated the results to show GMOs were harmful.

One paper by Infascelli has been retracted from Food and Nutrition Science, “Gamma-Glutamyl Transferase Activity in Kids Born from Goats Fed Genetically Modified Soybean.” The retraction note says the paper was pulled for duplication:

Continue reading Paper claiming GMO dangers retracted amid allegations of data manipulation

List of retractions, corrections grows for Duke researchers

cov200hDuke researcher Michael Foster and his former co-author Erin Potts-Kant are adding to their notice count with a major correction from late last year to a paper on how certain cells in mice respond to a pneumonia infection, citing “potential discrepancies in the data.”

The correction is actually a partial retraction: The note explains that parts of three figures should be discounted.

We’ve also recently unearthed multiple corrections and two retractions from the pair that we missed from earlier in 2015.

After questions about the data in the corrected paper arose, the authors were able to replicate most of the experiments in the paper, according to the note. But since the paper was published, the senior author passed away, closing her lab, so they couldn’t repeat all of the work.

Here’s the correction notice for “Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)−/− mice,” published in The Journal of Allergy and Clinical Immunology:

Continue reading List of retractions, corrections grows for Duke researchers

Authors retract two papers for “severe conflicts of author sequences”

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A group of authors has earned two retractions for a pair of papers on which they had “severe conflicts of author sequences,” according to the retraction note.

All of the authors were involved in a recent spate of compromised peer review that hit Springer journals back in August. Among the 64 retracted papers this summer, one included all of the authors on the two recently retracted papers, including first author Yan-Zhi Chen. Besides authorship issues, the latest two retractions also contain a “striking similarity to other publications,” according to the retraction notices.

The notes for the two papers are the same, except for the title of the paper. (They are also paywalled, tsk tsk!)

Here’s what the notes say:

Continue reading Authors retract two papers for “severe conflicts of author sequences”

Paper on plant immunity can’t fight off manipulation

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A paper on how plants respond to bacteria has an invader of its own — data manipulation.

The “irregularities and inappropriate data manipulation” were found in a figure produced by the first author, Ching-Wei Chen, whose LinkedIn page lists him as a student at the National Taiwan University. The authors were unable to replicate the results in the figure, according to the note.

The authors are doing more experiments to verify the main conclusion of the 2014 paper, “The Arabidopsis Malectin-Like Leucine-Rich Repeat Receptor-Like Kinase IOS1 Associates with the Pattern Recognition Receptors FLS2 and EFR and Is Critical for Priming of Pattern-Triggered Immunity,” published in The Plant Cell.

The retraction note explains the what happened in more detail:

Continue reading Paper on plant immunity can’t fight off manipulation

Second of 3 retractions appears for biologist, the result of “a substantial number of falsifications”

Screen Shot 2016-01-13 at 10.19.01 AMA cell biologist who falsifed Western blots has notched a second retraction, with one more expected after a investigation at Nanyang Technological University in Singapore.

First author Sudarsanareddy Lokireddy, now apparently a research fellow at Harvard, did not agree to the retraction, the result of “a substantial number of falsifications.”

In December, we covered the results of the NTU investigation, where Lokireddy used to work. During that investigation, he admitted to falsifying data, Research Integrity Officer Tony Mayer told us. The end result: three retractions.

One of those papers was retracted by Cell Metabolism in December. The second paper, published in Molecular Endocrinology, has been cited 52 times, according to Thomson Scientific’s Web of Knowledge. The retraction note explains which figures were falsified:

Continue reading Second of 3 retractions appears for biologist, the result of “a substantial number of falsifications”

IVF embryo paper pulled for plagiarism, errors, lack of permissions

6A journal is pulling an article (with approval of “most” of the authors) because a similar paper had already been published in Chinese.

That wasn’t the only problem with “Aneuploidy analysis of non-pronuclear embryos from IVF with use of array CGH: a case report,” published in the Journal of Molecular Histology. 

The retraction note lists the three things that led to the paper’s retraction:

Continue reading IVF embryo paper pulled for plagiarism, errors, lack of permissions

Cancer Cell paper under investigation following anonymous queries on PubPeer

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A Cancer Cell paper that caused a flurry of activity on the website PubPeer is under investigation, after the last author announced on the site that he’d requested a correction from the journal.

The 2012 paper sparked a lively dialogue last month on the post-publication discussion site, as commenters questioned Western blot images in which some bands appeared to be duplicates. The last author responded, noting he had alerted the journal to a “mishap,” and a correction would be forthcoming. However, some commenters remained unsatisfied, and questioned why the correction was taking so long to appear, as well as the explanation for what went wrong.

A spokesman from Cancer Cell confirmed to us the paper is under investigation:

Continue reading Cancer Cell paper under investigation following anonymous queries on PubPeer

Misidentified DNA leads authors to retract zebrafish cholesterol paper

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Authors are retracting a 2012 paper on cholesterol metabolism in zebrafish after realizing it included a case of mistaken identity in a DNA sequence crucial to some aspects of the experiment.  

A postdoc misidentified the plasmid in question after failing to fully sequence it before including it in the experiment. A technician in the lab found the mistake, last author Steven Farber, a researcher at the Carnegie Institution for Science in Maryland, explained:

When the omitted region was correctly sequenced we discovered it had an error.

He told us in a phone interview what that felt like:

We were like, holy crap.

Next came months of back and forth with the journal, discussing whether to correct or retract the paper. Farber tells us the mistake, which affects two figures,

was unfortunate. Most of the paper is in fact correct.

The paper, “Visualization of Lipid Metabolism in the Zebrafish Intestine Reveals a Relationship between NPC1L1-Mediated Cholesterol Uptake and Dietary Fatty Acid,” published in Chemistry & Biology, has been cited 21 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the detailed retraction note:  Continue reading Misidentified DNA leads authors to retract zebrafish cholesterol paper