Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘blood (journal) retractions’ Category

Cancer researcher contributed “false data” to 11 studies

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ori-logoA former cancer researcher has falsified data in 11 studies, according to the results of a investigation scheduled to be published in the Federal Register tomorrow.

The Office of Research Integrity’s findings are based on an inquiry at Virginia Commonwealth University, where Girija Dasmahapatra worked until July of this year, investigating possible therapies for cancer. The misconduct affected research funded by three grants from the National Institutes of Health. Steven Grant, a researcher at VCU, is the principal investigator on the grants, each of which total over $2 million in funding. All of the 11 affected papers will be corrected or retracted, according to the ORI notice.

Two of the papers containing “falsified and/or fabricated” data — a study on an experimental combination of drugs for blood cancer and one on chemotherapies for rare forms of lymphoma  — were covered in press releases by VCU.

According to the notice in the Federal Register:

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Correction “does not change the scientific meaning” of leukemia letter

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The journal Blood has issued a correction in a 2009 letter about the molecular underpinnings of chronic lymphocytic leukemia.

Despite the extent of the changes to a figure, “the error does not change the scientific meaning,” according to the erratum.

The article “p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia” was written in response to a 2009 Blood paper about the role of a microRNA in CLL. But its western blots were “assembled incorrectly,” leading to duplicated panels. Another set of panels was “shifted.”

So the authors repeated the experiments, and presented them in a correction. Here’s the correction notice in full, published earlier this month, including the figures in question:

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Stem cell researcher Jacob Hanna’s correction count updated to 10

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Jacob Hanna

Jacob Hanna

Thanks to some eagle-eyed readers, we’ve been alerted to some corrections for high profile stem cell scientist Jacob Hanna that we had missed, bringing our count to one retraction and 13 errata on 10 papers.

The problems in the work range from duplications of images, to inadvertent deletions in figures, to failures by his co-authors to disclose funding sources or conflicts of interest. Hanna is the first or last author on 4 of the papers, and one of several on the rest.

First up, a correction to a Cell paper on which Hanna is the first author:

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Cell biologist Hanna issues two errata; images mysteriously disappear from Imgur

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Jacob Hanna

Jacob Hanna

Cell biologist Jacob Hanna, the highly cited stem cell researcher currently at the Weizmann Institute of Science,  has posted a long erratum for a 2005 paper in Blood for “inadvertent mistakes,” among other issues; soon after, Hanna’s team issued another erratum for a 2009 Cell Stem Cell paper.

There’s more to tell: Last month, commenters on PubPeer noticed that images from at least 10 of the research papers Hanna coauthored in seven journals — that commenters had posted on the image hosting website Imgur and linked to on PubPeer — had been deleted.

Imgur did not confirm whether these specific images had been deleted, but told Retraction Watch:

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Stem cell researcher Hanna “working…to correct the unfortunate and inadvertent mistakes” in papers

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Jacob Hanna

Jacob Hanna of Israel’s Weizmann Institute has been a media darling for years, including as a member of the 2010 Technology Review 30 under 35 for his work with stem cells.

However, questions have been mounting about his research, both on PubPeer (which has critical comments for 15 papers he’s an author on) and in other stem cell labs, who have not been able to reproduce much of Hanna’s work.

We asked Hanna about a PubPeer entry specific to a 2005 paper in BloodCommenters have accused the authors of figure manipulation and possible data republication. Here’s a figure from that post: Read the rest of this entry »

Written by Cat Ferguson

December 17th, 2014 at 1:00 pm

A year after ORI report, hematology journal retracts faked paper

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bloodA year after an ORI report discredited the work of former University of Washington in Seattle researcher Andrew Aprikyan, one of the papers named in the report has finally been retracted.

Here’s the notice for “Impaired survival of bone marrow hematopoietic progenitor cells in cyclic neutropenia”:  Read the rest of this entry »

Written by Cat Ferguson

August 6th, 2014 at 9:30 am

Journal retracts stem cell study despite objections of most authors

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Gerold Feuer in 2008, via Upstate

Gerold Feuer in 2008, via Upstate

The journal Blood has retracted a 2010 paper over the objections of most of its authors, two of whom were found by their university to have used “fraudulent methods” to obtain the data.

We first reported on the case of Gerold Feuer last fall. The State University of New York (SUNY) Upstate Medical Center in Syracuse fired Feuer in 2010 after determining that he had misused state funds to enrich a company he had founded, HuMurine. A court agreed with many of the university’s claims, but ordered his reinstatement in 2012.

Meanwhile, as we noted last fall: Read the rest of this entry »

Contaminated cells force retraction of Blood paper

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blood414Blood has an interesting retraction of a 2011 paper on what a group of authors claimed was a new cell line — but which proved, apparently, to be a chimera.

The article, “Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC,” came from a team at Universität Duisburg-Essen, in Germany, and has been cited 21 times, according to Thomson Scientific’s Web of Knowledge. Here’s the abstract: Read the rest of this entry »

Blood retracts two red cell illustrations that “could have misled” readers

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blood cover214Blood has retracted two 2013 illustrations of red cells by researchers from South Africa and the United States because, somewhat confusingly, they didn’t conform to the journal’s criteria for publishing such material.

Here’s the notice for one of the images, “Red blood cell and platelet interactions in healthy females during early and late pregnancy, as well as postpartum”: Read the rest of this entry »

Retraction appears for stem cell researcher found to have used funds for his company’s gain

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Gerold Feuer in 2008, via Upstate

A stem cell journal is retracting a paper by Gerold Feuer, a researcher at the State University of New York (SUNY) Upstate Medical Center in Syracuse who was also found to have misused grants.

The Feuer story is complicated. Heralded in 2008 for landing $6.2 million in grants from the New York Stem Cell Board, Feuer was suspended in October 2010 while the university investigated allegations he had misused funds, specifically to funnel state dollars to HuMurine, a company he founded in 2008. In December 2010, Upstate said they had found evidence he had committed 53 acts of financial misconduct, and dismissed him.

From an August 2012 court ruling on a case Feuer brought to fight that dismissal: Read the rest of this entry »