Search Results for: western blot

Authors withdraw already-corrected JBC paper questioned on PubPeer

An assistant professor of neuroscience at Tufts has withdrawn a paper published last year after one round of corrections wasn’t enough to fix all of the study’s problems. The study, “Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein,” by Gizem Donmez and colleagues, had already … Continue reading Authors withdraw already-corrected JBC paper questioned on PubPeer

Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

The Journal of Neuroscience has retracted a 2012 paper by a group from Sweden’s Karolinska Institutet for what appears to be research misconduct. But more on that in a moment. The article, “The Existence of FGFR1-5-HT1A Receptor Heterocomplexes in Midbrain 5-HT Neurons of the Rat: Relevance for Neuroplasticity,” came from the lab of Kjell Fuxe, … Continue reading Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

Kidney International paper retracted after lab records “were improperly filed”

A group of University of California, Davis kidney researchers have retracted a paper after being unable to verify key parts of it. Here’s the detailed retraction notice for “Proteinuria decreases tissue lipoprotein receptor levels resulting in altered lipoprotein structure and increasing lipid levels,” published by Limin Wang, George Kaysen, and colleagues in Kidney International last … Continue reading Kidney International paper retracted after lab records “were improperly filed”

Nature corrects figures McGill committee found had been “intentionally contrived and falsified”

The second of two corrections by McGill researcher Maya Saleh for what a university committee called “intentionally contrived and falsified” figures has run in Nature. We reported in January that the McGill committee concluded that two figures in [a] Nature paper had been “intentionally contrived and falsified.” One of those figures was duplicated in a PNAS paper, … Continue reading Nature corrects figures McGill committee found had been “intentionally contrived and falsified”

Authors hit for image manipulation cycle, but don’t worry, they’ll resubmit retracted paper

Regrets were had, mistakes were made, but gosh-darn-it, they’re gonna resubmit that retracted paper in the future. Such is the message from a retraction of “Tsg101 Interacts with Herpes Simplex Virus 1 VP1/2 and Is a Substrate of VP1/2 Ubiquitin-Specific Protease Domain Activity,” from Italian virologists who admitted to copying and pasting their way into the … Continue reading Authors hit for image manipulation cycle, but don’t worry, they’ll resubmit retracted paper

Updated: Integrity “uncertain,” journal retracts stroke paper

Experimental & Molecular Medicine has retracted a 2012 paper on stroke by a group of South Korean researchers after learning that one of the figures in the article was unreliable. The article was titled “Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury,” and it came from a team at Hallym … Continue reading Updated: Integrity “uncertain,” journal retracts stroke paper

“Technical but fundamental errors” lead to retraction of brain tumor paper

The journal Neuro-Oncology has retracted a 2011 paper by a group of researchers in Japan who had purported to find a genetic mechanism for how fluorescence can be used to diagnose certain brain tumors. The paper, “Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors: CPOX expression and 5-ALA–induced fluorescence,” reported measurements using quantitative real-time … Continue reading “Technical but fundamental errors” lead to retraction of brain tumor paper

Diabetes paper retracted for “misgrouping errors” that remain under investigation

A group of researchers at the University of Minnesota have retracted a paper in Diabetes for image problems, but exactly what happened is still under investigation. Here’s the notice:

Mitochondrial fission paper falls for fusing data from earlier work

A team of neuroscientists in Japan has lost their 2012 article in Brain Research for duplicating elements of a figure from a paper they’d published earlier that year in another journal. The article, “Dynamic changes of mitochondrial fission proteins after transient cerebral ischemia in mice,” came from a lab at Okayama University. The last author … Continue reading Mitochondrial fission paper falls for fusing data from earlier work

ORI rules in longstanding University of Washington misconduct case

A case of alleged misconduct at the University of Washington in Seattle may finally be over. The Office of Research Integrity released its findings following an investigation into the work of Andrew Aprikyan, a former hematology researcher at the university. The Aprikyan case has dragged on for a decade. In 2010, the university fired the … Continue reading ORI rules in longstanding University of Washington misconduct case