Category: clinical study retractions

Dispute over author order torpedoes paper on syndrome linked to autism

At least one disgruntled co-author has triggered the retraction of a paper presenting a novel approach to treating a rare, genetically inherited condition.

The paper concerned research on Fragile X syndrome (FXS), characterized by both intellectual and physical abnormalities, which is linked autism. A compound that passed through phase 2 clinical trials in October 2015 appeared to partially treat FXS in mice in the study, published earlier this year.

The journal’s notice says the paper was retracted over a dispute among authors about the order in which they are listed on the paper: Continue reading Dispute over author order torpedoes paper on syndrome linked to autism

Journal issues note of concern, tips off university’s research integrity office

A journal has published an expression of concern (EoC) for a paper on cancer genetics in mice, over a concern about data in some gel panels.

The EoC for “Suppression of intestinal tumorigenesis in Apc mutant mice upon Musashi-1 deletion,” appeared Sept. 21 in Journal of Cell Science (JCS).

With the notice, the journal says:

Continue reading Journal issues note of concern, tips off university’s research integrity office

Journal to retract paper called “anti-vaccine pseudoscience”

A journal is planning to retract a paper that purported to link a component of vaccines to autism in mice.

The paper, about the effects of aluminum adjuvants in vaccines on the immune response in the brains of mice, is the second retraction for co-authors Christopher Shaw and Lucija Tomljenovic, of the University of British Columbia. The journal’s editor told us he and the authors are jointly retracting the paper. 

Just over a month old, the paper has already received plenty of criticism. Numerous commenters on PubPeer have allegedly identified image duplications and other problems with the paper. One commenter described “clear and deliberate” removal of control results in the paper, while others suggested gel bands were duplicated within the paper, and appear similar to those from another paper published in 2014 by Shaw and Tomljenovic. In a blog post, David Gorski, a professor and surgeon at Wayne State University, called the paper “antivaccine pseudoscience.”

Shaw, the paper’s last author, told us that his lab became aware of the PubPeer discussion a few weeks after publication:  Continue reading Journal to retract paper called “anti-vaccine pseudoscience”

Society recommends 9 retractions for co-author of researcher with record number of retractions

The Japanese Society of Anesthesiologists (JSA) has requested the retraction of nine additional papers by a co-author of fraudster Yoshitaka Fujii, after investigating allegations of fraud in dozens of papers.

According to the report, a committee investigated approximately 40 publications by Yuhji Saitoh of Yachiyo Medical Center and Tokyo Women’s Medical University and “identified ten publications with clear ethics violations, one of which has already been retracted.”

Saitoh has collaborated on many papers with Fujii, an anesthesia researcher with more than 180 retractions. As we reported, Saitoh resigned from the JSA when the investigation began, and the society permanently banned him. Continue reading Society recommends 9 retractions for co-author of researcher with record number of retractions

Early data on potential anti-cancer compound now in human trials was falsified, company admits

A pharmaceutical company has admitted that one of its former researchers falsified early data on a compound that’s designed to fight cancer, now in human trials.

The data, published as an abstract in August 2015 in the journal Cancer Research, reported a therapeutic benefit of acalabrutinib in a mouse model of pancreatic cancer. The compound, developed by the company Acerta Pharma, has also been the subject of additional trials published in the New England Journal of Medicine and Blood in 2015. The 2015 NEJM study, which had several authors in common with the Cancer Research abstract, showed the agent had “promising safety and efficacy profiles in patients” with relapsed chronic lymphocytic leukemia.

But an investigation into the data underlying the 2015 abstract shows some were falsified, prompting the journal to retract the abstract.

Ed Tucker, senior vice president of Medical Safety, Quality and Compliance at Acerta Pharma, told us that in August 2016 the company identified an issue with the data in the Cancer Research abstract and started an investigation:

Continue reading Early data on potential anti-cancer compound now in human trials was falsified, company admits

Second retraction for psychologist reveals clues about culprit behind misconduct

A social psychologist has retracted a second paper that contains “fabricated or manipulated data.”

The first retraction for William Hart at the University of Alabama — also due to data manipulation — appeared earlier this year. The notice raised some questions over authorship: Hart was the sole author, but he blamed the retraction on a graduate student who supplied the problematic data. The questions continued when Hart’s colleagues posted blogs about the problems that occurred in Hart’s lab, using a pseudonym to describe the student, who apparently admitted to fabricating data.  

The author of one of those blogs, Hart’s colleague Alexa Tullett, told us in March that she was retracting another paper she wrote with Hart and the unnamed graduate student. Recently, she confirmed this latest retraction is that paper.

Looking at the author list of the newest retraction, by process of elimination, we now have a lead on the identity of the graduate student who allegedly took responsibility for the misconduct.

Tullett told us:

Continue reading Second retraction for psychologist reveals clues about culprit behind misconduct

Co-author of now-retracted paper about video games apparently demoted to “lecturer” by uni

Jodi Whitaker, via University of Arizona

A researcher who co-authored a paper about violent video games that was retracted earlier this year appears to have changed positions, according to her website.

After her PhD was revoked by The Ohio State in August, Jodi Whitaker’s listed position at the University of Arizona changed from “assistant professor” to “lecturer.” The page also has removed the information about her PhD, and lists her highest degree as a master’s degree in social psychology from the University of Michigan.

Whitaker has also removed the retracted paper — which includes the title “Boom, Headshot!” — from her list of publications.

Continue reading Co-author of now-retracted paper about video games apparently demoted to “lecturer” by uni

ORI finds misconduct in case of biologist paid $100K by university to leave

A biologist who studied the impact of diabetes on the eye inappropriately altered data in five images from three papers, according to a new finding of misconduct issued by the U.S. Office of Research Integrity (ORI).

Readers may be familiar with the subject of the findings: Azza El-Remessy, a former tenured associate professor at the University of Georgia (UGA) in Athens, spoke to us earlier this year about her battle with UGA. In June 2016, UGA found her guilty of research misconduct and recommended she be terminated. El-Remessy fought back, hiring a lawyer to contest the findings, and the university ultimately paid her $100,000 to leave. (For more, here’s UGA’s June 2016 investigation report and the settlement agreement between UGA and El-Remessy.) Continue reading ORI finds misconduct in case of biologist paid $100K by university to leave

So, was it plagiarism? Journal retracts three papers over “citation and attribution errors”

When several recent submissions raised a red flag, a pediatrics journal decided to investigate. The journal, Pediatrics in Review, discovered “citation and attribution errors” in three case studies, which the journal has now retracted.  

Luann Zanzola, the managing editor of the journal, explained that the editors caught the errors when they scanned the three papers—one published in 2014 and two in 2015—using the plagiarism detection software, iThenticate. Zanzola told us that the three case studies “were flagged for high iThenticate scores,” and when the authors could not adequately explain the amount of text overlap, the editors retracted the papers.

The retraction notices for the three papers, published in the journal’s September 2017 issue, are identical: Continue reading So, was it plagiarism? Journal retracts three papers over “citation and attribution errors”

Journal adds concern notice to paper by psychologist Jens Förster

A social psychology journal has added an expression of concern to a paper by prominent social psychologist Jens Förster, whose work has been subject to much scrutiny.

This is the latest in a long-running saga involving Förster. The 2012 paper in the Journal of Experimental Social Psychology had been flagged by a 2015 report describing an investigation into Förster’s work, which had concluded the paper likely contained unreliable data. Several other papers that received similar designations in that report have either been retracted or received expressions of concern (EoC).

The (paywalled) notice provides a lengthy explanation for why the journal chose to add an EoC, rather than retract the paper, as the University of Amsterdam had recommended. Here is an excerpt:

Continue reading Journal adds concern notice to paper by psychologist Jens Förster